anti-Ubiquitin Protein Ligase E3B (UBE3B) Antikörper

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Zusätzlich bieten wir Ihnen UBE3B Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBE3B 89910 Q7Z3V4
UBE3B 117146 Q9ES34
UBE3B 687633  
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Top anti-UBE3B Antikörper auf antikoerper-online.de

Showing 10 out of 21 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-UBE3B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  293T cell lysate 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of UBE3B staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wi Western blot analysis of UBE3B expression in HEK293T (A), Jurkat (B) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from Jurkat cells, using UBE3B Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6272453 at 1/100 staining Human liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis UBE3B using Jurkat whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB   100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL 11 bis 16 Tage
$312.70
Details
Human Kaninchen Unkonjugiert WB UBE3B antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
$449.29
Details
Human Kaninchen Unkonjugiert WB Western blot (WB) analysis of UBE3B polyclonal antibody at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:SGC7901 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug) 100 μL 6 bis 11 Tage
$350.00
Details

Am meisten referenzierte anti-UBE3B Antikörper

  1. Cow (Bovine) Polyclonal UBE3B Primary Antibody für WB - ABIN2781245 : Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008 (PubMed)

Weitere Antikörper gegen UBE3B Interaktionspartner

Human Ubiquitin Protein Ligase E3B (UBE3B) Interaktionspartner

  1. we present four patients with five novel UBE3B mutations and propose the inclusion of clinical features to the characteristics of Kaufman oculocerebrofacial syndrome, including prominence of the cheeks and limb anomalies.

  2. The E3 ligase activity of UBE3B is regulated by its interaction with calmodulin via the N-terminal IQ domain.

  3. Sanger sequencing was negative for the DOORS syndrome gene TBC1D24 but exome sequencing identified a homozygous deletion in UBE3B (NM_183415:c.3139_3141del, p.1047_1047del) located within the terminal portion of the HECT domain

  4. UBE3B encodes a widely expressed protein ubiquitin ligase E3B, which, when mutated in both alleles, causes Kaufman oculocerebrofacial syndrome.

  5. UBE3B mutations cause a clinically recognizable and possibly underdiagnosed syndrome named the Kaufman oculocerebrofacial syndrome

  6. data provide evidence that Kaufman oculocerebrofacial syndrome is caused by UBE3B loss of function, and further demonstrate the impact of misregulation of protein ubiquitination on development and growth.

  7. Our data reveal the pleiotropic effects of UBE3B deficiency and reinforce the physiological importance of ubiquitination in neuronal development and function in mammals.

  8. UBE3B is a novel E3 ligase, with a HECT-domain which constitutes the active site for ubiquitin transfer

  9. the apparent occurrence of an unusual TG 3' splice site in intron 25 is discussed

Mouse (Murine) Ubiquitin Protein Ligase E3B (UBE3B) Interaktionspartner

  1. Our data reveal the pleiotropic effects of UBE3B deficiency and reinforce the physiological importance of ubiquitination in neuronal development and function in mammals.

UBE3B Antigen-Profil

Protein Überblick

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit UBE3B

  • ubiquitin protein ligase E3B (UBE3B) Antikörper
  • ubiquitin protein ligase E3B (ube3b) Antikörper
  • ubiquitin-protein ligase E3B (LOC581811) Antikörper
  • ubiquitin protein ligase E3B L homeolog (ube3b.L) Antikörper
  • ubiquitin protein ligase E3B (Ube3b) Antikörper
  • AI449831 Antikörper
  • AU020130 Antikörper
  • BPIDS Antikörper
  • si:dkey-189p24.3 Antikörper

Bezeichner auf Proteinebene für UBE3B

ubiquitin-protein ligase E3B , ubiquitin protein ligase E3B , ubiquitin-protein ligase E3B-like , ubiquitin protein ligase E3

GENE ID SPEZIES
452223 Pan troglodytes
780337 Xenopus (Silurana) tropicalis
581811 Strongylocentrotus purpuratus
100028483 Monodelphis domestica
100338868 Oryctolagus cuniculus
100449551 Pongo abelii
100475409 Ailuropoda melanoleuca
100592402 Nomascus leucogenys
100381000 Xenopus laevis
100394165 Callithrix jacchus
556864 Danio rerio
374194 Gallus gallus
89910 Homo sapiens
486311 Canis lupus familiaris
512750 Bos taurus
117146 Mus musculus
687633 Rattus norvegicus
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