anti-UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) Antikörper

UPF3A encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Zusätzlich bieten wir Ihnen UPF3A Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UPF3A 67031  
UPF3A 361176  
UPF3A 65110 Q9H1J1
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Top anti-UPF3A Antikörper auf antikoerper-online.de

Showing 10 out of 33 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Ziege Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Rind (Kuh) Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Western Blot analysis of UPF3A expression in transfected 293T cell line by UPF3A monoclonal antibody (M06), clone 2E2.<br><br>Lane 1: UPF3A transfected lysate(51 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunoperoxidase of monoclonal antibody to UPF3A on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.45 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of UPF3A expression in transfected 293T cell line by UPF3A MaxPab polyclonal antibody.<br><br>Lane 1: UPF3A transfected lysate(48.73 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to UPF3A on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

UPF3A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Rat (Rattus)


Human , , ,
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Am meisten referenzierte anti-UPF3A Antikörper

  1. Cow (Bovine) Polyclonal UPF3A Primary Antibody für ELISA - ABIN4364428 : Tarpey, Raymond, Nguyen, Rodriguez, Hackett, Vandeleur, Smith, Shoubridge, Edkins, Stevens, OMeara, Tofts, Barthorpe, Buck, Cole, Halliday, Hills, Jones, Mironenko, Perry, Varian, West, Widaa, Teague et al.: Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. ... in Nature genetics 2007 (PubMed)

Weitere Antikörper gegen UPF3A Interaktionspartner

Mouse (Murine) UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) Interaktionspartner

  1. Analysis revealed that UPF3A is a broadly acting nonsense-mediated RNA decay inhibitor. This discovery implies that UPF3A and UPF3B (zeige UPF3B Antikörper) do not primarily work in a complementary or redundant manner as previously supposed; instead, they oppose each other, allowing this paralog pair to serve as a molecular rheostat to modulate the level of gene expression during development.

Human UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) Interaktionspartner

  1. The complex between the interacting domains of human UPF2 (zeige UPF2 Antikörper) and UPF3b (zeige UPF3B Antikörper) at a 1.95 A resolution.

  2. hUpf3a is much less active than hUpf3b (zeige UPF3B Antikörper) to induce NMD and to stimulate translation

  3. Results suggest that UPF3A levels are tightly regulated by a post-transcriptional switch to maintain appropriate levels of NMD substrates in cells containing different levels of UPF3B (zeige UPF3B Antikörper).

UPF3A Antigen-Profil

Protein Überblick

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit UPF3A

  • UPF3 regulator of nonsense transcripts homolog A (yeast) (Upf3a) Antikörper
  • UPF3A, regulator of nonsense mediated mRNA decay (Upf3a) Antikörper
  • UPF3 regulator of nonsense transcripts homolog A (yeast) (UPF3A) Antikörper
  • UPF3A, regulator of nonsense mediated mRNA decay (UPF3A) Antikörper
  • UPF3A, regulator of nonsense mediated mRNA decay (upf3a) Antikörper
  • 2600001C03Rik Antikörper
  • 4930546M19Rik Antikörper
  • HUPF3A Antikörper
  • RENT3A Antikörper
  • si:dkey-21o13.6 Antikörper
  • UPF3 Antikörper
  • UPF3A Antikörper

Bezeichner auf Proteinebene für UPF3A

UPF3 regulator of nonsense transcripts homolog A , regulator of nonsense transcripts 3A , UPF3 regulator of nonsense transcripts homolog A (yeast) , regulator of nonsense transcripts 3A-like , hUpf3 , nonsense mRNA reducing factor 3A , up-frameshift suppressor 3 homolog A

GENE ID SPEZIES
67031 Mus musculus
361176 Rattus norvegicus
418734 Gallus gallus
452689 Pan troglodytes
529442 Bos taurus
607836 Canis lupus familiaris
100434953 Pongo abelii
65110 Homo sapiens
566608 Danio rerio
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