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anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Antikörper

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. Zusätzlich bieten wir Ihnen U2AF Homology Motif (UHM) Kinase 1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UHMK1 127933 Q8TAS1
UHMK1 16589 P97343
UHMK1 246332 Q63285
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Top anti-U2AF Homology Motif (UHM) Kinase 1 Antikörper auf antikoerper-online.de

Showing 10 out of 89 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-KIS Pab (ABIN392641) in mouse heart tissue lysate. KIS (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Human Maus Unkonjugiert FACS, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
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Human Kaninchen Unkonjugiert WB Western Blot: KIST Antibody [NBP1-31094] - HeLa S3 7.5% SDS PAGE diluted at 1:1000 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Maus Kaninchen Unkonjugiert WB Mouse Uhmk1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Uhmk1 antibody detected the Uhmk1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
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Rind (Kuh) Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
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Hund Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Western Blot at 1:1000 dilution Lane 1: human skeletal muscle lysate Lane 2: A-673 whole cell lysate Lysates/proteins at 20 ug per lane. Antibody is used in Western blot to detect KIST in K562 cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details

UHMK1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-U2AF Homology Motif (UHM) Kinase 1 Antikörper

  1. Human Polyclonal UHMK1 Primary Antibody für IHC (p), WB - ABIN392641 : Bièche, Manceau, Curmi, Laurendeau, Lachkar, Leroy, Vidaud, Sobel, Maucuer: Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human. in Brain research. Molecular brain research 2003 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal UHMK1 Primary Antibody für ELISA - ABIN4228447 : Nakamura, Okinaka, Hirano, Ono, Sugimoto, Shigeno, Fujisawa, Shinjo, Ohnishi: KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells. in Leukemia research 2008 (PubMed)

Weitere Antikörper gegen U2AF Homology Motif (UHM) Kinase 1 Interaktionspartner

Human U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Interaktionspartner

  1. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians.

  2. Moreover, we showed that CATS and KIS antagonize the transactivation capacity of CALM/AF10 (zeige MLLT10 Antikörper).In summary, our results show that CATS interacts with and is a substrate for KIS, suggesting that KIS regulates CATS function

  3. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored.

  4. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens.

  5. KIS gene was overexpressed in NF1 (zeige NF1 Antikörper)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1 (zeige NF1 Antikörper)-associated tumors.

  6. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 (zeige RGS4 Antikörper) and NOS1AP (zeige NOS1AP Antikörper).

  7. KIS promoter is activated by serum-responsive GABP binding to Ets (zeige ETS1 Antikörper)-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression

  8. Results show that KIS is a direct transcriptional target of FoxM1 (zeige FOXM1 Antikörper).

  9. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia

  10. A follow up article showing further association between markers in UHMK1 and schizophrenia in a London based sample. Association replicated in an independent Scottish sample.

Mouse (Murine) U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Interaktionspartner

  1. The absence of KIS results in a significant decrease in AMPA (zeige GRIA3 Antikörper) receptors in dendritic spines.

  2. disregulation of gene expression due to KIS inactivation affects specific brain functions.

  3. Uhmk1 was concentrated in the nucleus, but cycled rapidly between nucleus and cytosol.

  4. Endogenous mouse KIS was detected mainly in the nucleus of asynchronously growing cells. During serum starvation, its expression was reduced.

  5. KIS is a component of the molecular device that modulates translation in RNA-transporting granules as a result of local signals.

  6. Phosphorylation of p27Kip1 (zeige CDKN1B Antikörper) by KIS leads to cell-cycle progression, whereas the target sequence and the physiological relevance of KIS-mediated stathmin (zeige STMN1 Antikörper) phosphorylation in VSMCs

U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Antigen-Profil

Protein Überblick

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit UHMK1

  • U2AF homology motif kinase 1 (UHMK1) Antikörper
  • U2AF homology motif (UHM) kinase 1 (uhmk1) Antikörper
  • U2AF homology motif (UHM) kinase 1 (UHMK1) Antikörper
  • U2AF homology motif (UHM) kinase 1 (Uhmk1) Antikörper
  • U2AF homology motif kinase 1 (Uhmk1) Antikörper
  • 4732477C12Rik Antikörper
  • 4930500M09Rik Antikörper
  • AA673513 Antikörper
  • AI449218 Antikörper
  • AU021979 Antikörper
  • KIS Antikörper
  • Kist Antikörper
  • P-CIP2 Antikörper
  • UHMK1 Antikörper
  • zgc:153241 Antikörper

Bezeichner auf Proteinebene für UHMK1

U2AF homology motif (UHM) kinase 1 , kinase interacting stathmin , serine/threonine-protein kinase Kist , serine/threonine-protein kinase Kist-like , KIS protein kinase , PAM COOH-terminal interactor protein 2 , kinase interacting with leukemia-associated gene (stathmin) , U2AF homology motif kinase 1 , kinase interacting with stathmin , P-CIP2

GENE ID SPEZIES
424369 Gallus gallus
469560 Pan troglodytes
720105 Macaca mulatta
767721 Danio rerio
100058796 Equus caballus
100408720 Callithrix jacchus
100585553 Nomascus leucogenys
100622137 Sus scrofa
127933 Homo sapiens
16589 Mus musculus
478986 Canis lupus familiaris
246332 Rattus norvegicus
538770 Bos taurus
100172072 Pongo abelii
Ausgewählte Anbieter für anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Antikörper
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