Tumor-Associated Calcium Signal Transducer 2 Proteine (TACSTD2)

This intronless gene encodes a carcinoma-associated antigen. Zusätzlich bieten wir Ihnen TACSTD2 Antikörper (173) und TACSTD2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TACSTD2 4070 P09758
TACSTD2 56753 Q8BGV3
TACSTD2 494343 Q6P9Z6
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Showing 10 out of 26 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Maus Fc Tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$285.35
Details
Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$285.35
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$285.35
Details
Baculovirus infected Insect Cells Human His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
Human Cells Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$150.00
Details

TACSTD2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , , , ,
Mouse (Murine) , ,
, , ,
Rat (Rattus)

Weitere Proteine zu Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaktionspartnern

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaktionspartner

  1. Study demonstrated that TROP2 expression was increased in glioblastoma tissues and glioblastoma cell lines. High TROP2 expression was significantly correlated with the poor survival of glioblastoma patients.

  2. The results suggest that TROP2 expression could be an effective prognostic biomarker for oral squamous cell carcinoma

  3. TROP-2, SLP-2 and CD56 were effective diagnostic markers for PTC, especially when they were combined to use.

  4. Trop2 has a potential role in the promotion of EMT in BC.

  5. these results suggested that TROP2 may promote osteosarcoma cell proliferation and migration via PI3K/AKT signaling and may serve as a novel treatment target for osteosarcoma .

  6. TACSTD2 downregulation is associated with hepatocellular carcinoma.

  7. findings demonstrate that a membranous TROP-2 staining pattern is highly specific for PTC, which may serve as a potential diagnostic marker aiding in the accurate classification of morphologically equivocal thyroid follicular-patterned lesions

  8. TROP2 promoted the proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.

  9. The results from clinical specimens showed that Trop2 expression correlated with MMP2 expression in primary thyroid cancer. The current study suggests that elevated expression of Trop2 may represent an important molecular hallmark that is biologically and clinically relevant to the progression of thyroid cancer.

  10. these results suggest a differential role for TROP2 in different lung cancer subtypes

  11. Results show that TROP2 expression is up-regulated in gastric tumor and its co-expression with AREG protein is associated with TNM stage, tumor size, lymph node metastases, and distant metastases.

  12. Our findings indicate that the expression of Trop-2 is a stringent predictor of tumor response to AKT inhibitors. They also support the identification of target-activatory pathways, as efficient predictors of response in precision cancer therapy.

  13. Findings suggest that high TROP2 expression identifies distinct cell sub-populations in androgen-sensitive and androgen-independent prostate tumors and that it may be a predictive biomarker for prostate cancer treatment response in androgen-sensitive tumors.

  14. TROP2 may play a crucial role in COPD by affecting basal cells function and thus airway remodeling through increased basal cells hyperplasia

  15. TROP2 was overexpressed specifically in the majority of epithelial ovarian cancer and may be a novel prognostic biomarker

  16. we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 and galectin-3

  17. TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma

  18. The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

  19. We identified a homozygous TACSTD2 missense mutation, c.551A>G, p.(Tyr184Cys), in the affected family members. Both parents were heterozygous for the mutation, and unaffected siblings were either heterozygous or homozygous wild-type for this allele.

  20. Our results expand the mutational spectrum of TACSTD2 in patients with gelatinous drop-like corneal dystrophy (GDLD).

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaktionspartner

  1. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  2. Trop2 is a regulator of self-renewal, proliferation, and transformation

  3. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  4. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

  5. In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.

  6. Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.

  7. Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics.

TACSTD2 Protein Überblick

Protein Überblick

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Genbezeichner und Symbole assoziert mit TACSTD2

  • tumor associated calcium signal transducer 2 (TACSTD2)
  • tumor-associated calcium signal transducer 2 (Tacstd2)
  • tumor associated calcium signal transducer 2 (Tacstd2)
  • C80403 Protein
  • EGP-1 Protein
  • EGP1 Protein
  • GA733-1 Protein
  • GA7331 Protein
  • GP50 Protein
  • Ly97 Protein
  • M1S1 Protein
  • Prp1 Protein
  • TROP2 Protein

Bezeichner auf Proteinebene für TACSTD2

40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1 , tumor-associated calcium signal transducer 2 , tumor associated calcium signal transducer 2

GENE ID SPEZIES
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
100730427 Cavia porcellus
610286 Canis lupus familiaris
Ausgewählte Anbieter für TACSTD2 Proteine (TACSTD2)
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