anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antikörper

This intronless gene encodes a carcinoma-associated antigen. Zusätzlich bieten wir Ihnen TACSTD2 Proteine (18) und TACSTD2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TACSTD2 22004 P58774
TACSTD2 4070 P09758
TACSTD2 494343 Q6P9Z6
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Top anti-TACSTD2 Antikörper auf antikoerper-online.de

Showing 10 out of 173 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert CyTOF, FACS, IHC, WB TROP-2 in Human Brain. TROP-2 was detected in immersion fixed paraffin-embedded sections of human brain (frontal cortex) using Goat Anti-Human TROP-2 Antigen Affinity-purified Polyclonal Antibody. Detection of Human TROP-2 by Western Blot. Western blot shows lysates of NCI-N87 human gastric carcinoma cell line. PVDF membrane was probed with 1 ug/mL of Goat Anti-Human TROP-2 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$433.55
Details
Human Maus Unkonjugiert FACS, IHC   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$194.19
Details
Human Ziege Unkonjugiert ELISA, WB ABIN308423 (0.2 ug/ml) staining of Human Prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert CC, IF, IF/ICC, IHC (p) Immunofluorescence staining of human TROP2 in MCF-7 cells with mouse monoclonal antibody (15 µg/mL). The image showing membrane staining of MCF-7 cells. Immunochemical staining of human TROP2 in human placenta with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of cytotrophoblast. 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$218.90
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of TACSTD2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TACSTD2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus APC FACS Detection of TROP-2 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human TROP-2 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Maus Ziege Fluorescein FACS Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$299.00
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of TROP-2 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human TROP-2 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$328.90
Details
Maus Ziege APC FACS Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$410.55
Details
Maus Ziege Unkonjugiert CyTOF, FACS, ICC, IHC, WB Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 Antigen Affinity-purified Polyclonal Antibody. TROP-2 in XB2 Mouse Cell Line. TROP-2 was detected in immersion fixed XB2 mouse teratoma keratinocyte cell line using Goat Anti-Mouse TROP-2 Antigen Affinity-purified Polyclonal Antibody at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsﾙ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$440.45
Details

TACSTD2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TACSTD2 Antikörper

  1. Human Polyclonal TACSTD2 Primary Antibody für CyTOF, FACS - ABIN4900496 : Ambrogi, Fornili, Boracchi, Trerotola, Relli, Simeone, La Sorda, Lattanzio, Querzoli, Pedriali, Piantelli, Biganzoli, Alberti: Trop-2 is a determinant of breast cancer survival. in PLoS ONE 2014 (PubMed)
    Show all 9 Pubmed References

  2. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody für CyTOF, FACS - ABIN4900492 : Eisenwort, Jurkin, Yasmin, Bauer, Gesslbauer, Strobl: Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. in The Journal of investigative dermatology 2011 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal TACSTD2 Primary Antibody für FACS, IHC - ABIN2689944 : Bobos, Kotoula, Kaloutsi, Karayannopoulou, Papadimitriou, Kostopoulos: Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma. in Histology and histopathology 2009 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal TACSTD2 Primary Antibody für CyTOF, FACS - ABIN4900015 : Yamaguchi, Nishii, Nakamura, Aoki, Hirai, Uchida, Sakuma, Hamada: Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. in Biochemical and biophysical research communications 2016 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal TACSTD2 Primary Antibody für CyTOF, FACS - ABIN4900016 : Frederick, Helfrich, Coldren, Zheng, Chan, Bunn, Raben: Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal TACSTD2 Primary Antibody für FACS - ABIN4897042 : Hussain, Lawrence, Taylor, Lo, Frydenberg, Ellem, Furic, Risbridger: Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations. in PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal TACSTD2 Primary Antibody für IF (p) - ABIN918712 : Zhou, Copeland, Otto-Duessel, He, Markel, Synold, Jones: Low Testosterone Alters the Activity of Mouse Prostate Stem Cells. in The Prostate 2016 (PubMed)

  8. Human Polyclonal TACSTD2 Primary Antibody für ELISA, WB - ABIN316346 : Shimada, Kano, Ishiyama, Okubo, Iijima, Morishita, Minami, Inadome, Shu, Sugita, Takeuchi, Noguchi: Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development. in Cancer science 2005 (PubMed)

  9. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody für FACS - ABIN4897798 : Stoyanova, Goldstein, Cai, Drake, Huang, Witte: Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling. in Genes & development 2012 (PubMed)

Weitere Antikörper gegen TACSTD2 Interaktionspartner

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaktionspartner

  1. Stress fibre formation and up-regulation of alpha-smooth muscle actin (zeige ACTG2 Antikörper) (alphaSMA (zeige ACTA2 Antikörper)) induced by TGFbeta2 could be reversed by Tpm1 (zeige TPM1 Antikörper)/2 knock-down by siRNA.

  2. Trop2 marks fetal glandular epithelial cells of the stomach, growing as spheroids when cultured ex vivo. In adults, upon injury, Trop2 expression is reactivated in regenerative cells together with part of a fetal-like genetic program.

  3. Trop-2 promotes an alpha5beta1 integrin-dependent pro-metastatic signaling pathway in PCa (zeige ENPP1 Antikörper) cells and that the altered expression of Trop-2 may be utilized for early identification of capsule-invading PCa (zeige ENPP1 Antikörper).

  4. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  5. our findings help to establish a close functional link between Trop2 and MSCs, and to provide a tool for future investigation of Trop2 in other types of stem cells

  6. data suggest that Trop2 regulates cell proliferation and motility and that it does so by regulating the ERK (zeige EPHB2 Antikörper) pathway and several critical components of the cell migration apparatus

  7. Trop2 plays a cardioprotective role by promoting cardiac c-kit (zeige KIT Antikörper)+ cell proliferation and inhibition of apoptosis in the acute phase of myocardial infarction.

  8. Trop2 is a regulator of self-renewal, proliferation, and transformation

  9. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  10. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaktionspartner

  1. The results from clinical specimens showed that Trop2 expression correlated with MMP2 (zeige MMP2 Antikörper) expression in primary thyroid cancer. The current study suggests that elevated expression of Trop2 may represent an important molecular hallmark that is biologically and clinically relevant to the progression of thyroid cancer.

  2. these results suggest a differential role for TROP2 in different lung cancer subtypes

  3. Results show that TROP2 expression is up-regulated in gastric tumor and its co-expression with AREG (zeige AREG Antikörper) protein is associated with TNM (zeige ODZ1 Antikörper) stage, tumor size, lymph node metastases, and distant metastases.

  4. Our findings indicate that the expression of Trop-2 is a stringent predictor of tumor response to AKT (zeige AKT1 Antikörper) inhibitors. They also support the identification of target-activatory pathways, as efficient predictors of response in precision cancer therapy.

  5. Findings suggest that high TROP2 expression identifies distinct cell sub-populations in androgen-sensitive and androgen-independent prostate tumors and that it may be a predictive biomarker for prostate cancer treatment response in androgen-sensitive tumors.

  6. TROP2 may play a crucial role in COPD (zeige ARCN1 Antikörper) by affecting basal cells function and thus airway remodeling through increased basal cells hyperplasia

  7. TROP2 was overexpressed specifically in the majority of epithelial ovarian cancer and may be a novel prognostic biomarker

  8. we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 (zeige KRT19 Antikörper) and galectin-3 (zeige LGALS3 Antikörper)

  9. TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma

  10. The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

TACSTD2 Antigen-Profil

Protein Überblick

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Genbezeichner und Symbole assoziert mit TACSTD2

  • tropomyosin 2, beta (Tpm2) Antikörper
  • tumor associated calcium signal transducer 2 (TACSTD2) Antikörper
  • tumor-associated calcium signal transducer 2 (Tacstd2) Antikörper
  • C80403 Antikörper
  • EGP-1 Antikörper
  • EGP1 Antikörper
  • GA733-1 Antikörper
  • GA7331 Antikörper
  • GP50 Antikörper
  • Ly97 Antikörper
  • M1S1 Antikörper
  • Prp1 Antikörper
  • Tpm-2 Antikörper
  • Trop-2 Antikörper
  • TROP2 Antikörper

Bezeichner auf Proteinebene für TACSTD2

tropomyosin beta chain , 40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1

GENE ID SPEZIES
22004 Mus musculus
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
Ausgewählte Anbieter für anti-TACSTD2 (TACSTD2) Antikörper
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