anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Antikörper

TOP1MT encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. Zusätzlich bieten wir Ihnen TOP1MT Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TOP1MT 72960 Q8R4U6
TOP1MT 116447 Q969P6
TOP1MT 300029 Q6IM78
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Top anti-TOP1MT Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TOP1MT Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of TOP1MT using COLO205 whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Maus CF®405S FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF405M FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®488A FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®543 FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®555 FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®568 FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®594 FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details
Human Maus CF®640R FACS, IF, IHC (f)   100 μL 3 bis 4 Tage
$231.38
Details

Weitere Antikörper gegen TOP1MT Interaktionspartner

Mouse (Murine) Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Interaktionspartner

  1. Study demonstrated that lack of TOP1MT results in delayed and decreased tumor growth due to impaired mitochondrial translation. The TOP1MT genomic signature profile, based on mouse model for Top1mt-KO liver cancers, is correlated with enhanced survival of hepatocellular carcinoma patients.

  2. TOP1MT acts as a topological barrier and regulator for mtDNA transcription and D-loop formation

Human Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Interaktionspartner

  1. Study demonstrated that lack of TOP1MT results in delayed and decreased tumor growth due to impaired mitochondrial translation. The TOP1MT genomic signature profile, based on mouse model for Top1mt-KO liver cancers, is correlated with enhanced survival of hepatocellular carcinoma patients.

  2. This report was the first to focus on the role of TOP1MT in tumors. We identified a new mechanism underlying TOP1MT-deficient gastric cancer (GC) metastasis and showed that TOP1MT played an important role in cancer cells.

  3. Data indicate that the different coordination geometry achieved by the two transition metal ions has an important role in modulating their efficiency as topoisomerase I inhibitors.

  4. DNA topoisomerase I stimulates BLM helicase activity on a nucleolar-relevant RNA:DNA hybrid.

  5. Data reported in this paper indicate that hTop IB does not confer to the cells radio-resistance, but the kinetic analysis of both DNA repair rate as well as colonies growth, demonstrates that the cells containing hTop IB show a more efficient rescue from IR injury.

TOP1MT Antigen-Profil

Protein Überblick

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit TOP1MT

  • topoisomerase (DNA) I, mitochondrial (TOP1MT) Antikörper
  • DNA topoisomerase 1, mitochondrial (Top1mt) Antikörper
  • DNA topoisomerase I mitochondrial (TOP1MT) Antikörper
  • DNA topoisomerase I mitochondrial (Top1mt) Antikörper
  • 2900052H09Rik Antikörper
  • TOP1 Antikörper

Bezeichner auf Proteinebene für TOP1MT

DNA topoisomerase I, mitochondrial , mitochondrial topoisomerase I , mitochondrial topoisomerase IB , DNA topoisomerase 1, mitochondrial

GENE ID SPEZIES
408025 Gallus gallus
72960 Mus musculus
116447 Homo sapiens
300029 Rattus norvegicus
472883 Pan troglodytes
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