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TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. Zusätzlich bieten wir Ihnen Thymic Stromal Lymphopoietin Kits (88) und Thymic Stromal Lymphopoietin Proteine (47) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal TSLP Primary Antibody für IHC (p), IHC - ABIN5563670
Levin, Koelling, Friend, Isaksen, Ziegler, Perlmutter, Farr: Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. in Journal of immunology (Baltimore, Md. : 1950) 1999
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Human Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN258390
Quentmeier, Drexler, Fleckenstein, Zaborski, Armstrong, Sims, Lyman: Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. in Leukemia 2001
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Human Polyclonal TSLP Primary Antibody für IF (p), IHC (p) - ABIN668766
Sakitani, Nonaka, Shibata, Furukawa, Yoshihara: Increased Expression of Thymic Stromal Lymphopoietin and Its Receptor in Kimura's Disease. in ORL; journal for oto-rhino-laryngology and its related specialties 2015
Human Polyclonal TSLP Primary Antibody für IHC (p), ELISA - ABIN2476988
Liu, Soumelis, Watanabe, Ito, Wang, Malefyt, Omori, Zhou, Ziegler: TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. in Annual review of immunology 2007
Mouse (Murine) Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN4363149
Caglayan Sozmen, Karaman, Cilaker Micili, Isik, Arikan Ayyildiz, Bagriyanik, Uzuner, Karaman: Resveratrol ameliorates 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesions through effects on the epithelium. in PeerJ 2016
presence of epithelium-derived TSLP in the eustachian tubes plays important role in the onset of eosinophilic otitis media
a new mechanism of T cell stimulation in human skin was identified, demonstrating the direct induction of T cell migration by TSLP in the absence of DCs.
the secretion of TSLP by keratinocytes is induced by the HIV-1 viral synapse in a miR (zeige MLXIP Antikörper)-375 controlled manner
production increased at skin sites of ovalbumin (zeige OVA Antikörper) sensitization
Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 (zeige IL33 Antikörper) levels.
short and long thymic stromal lymphopoietin isoforms have roles in house dust mite-induced asthmatic airway epithelial barrier disruption
DeltaNp73 was abundantly expressed in the atopic dermatitis epidermis and increased the release of TSLP via NF-kappaB (zeige NFKB1 Antikörper) activation.
this study shows that long form of thymic stromal lymphopoietin of keratinocytes is induced by protein allergens
we found that activation of the protease-activated receptor 1 (PAR1 (zeige F2R Antikörper)) induced secretion of TSLP by the corneal stromal cells... we proposed that TSLP might function as the link between increased protease activity and inflammatory responses or itch sensation in the corneas
TSLP-HOTAIR axis also plays a protective role in low-density lipoprotein (ox-LDL)-induced Endothelial cells' injury.
findings suggest a role of TSLP in directly promoting Th2 cell effector function and support the notion of TSLP as a key driver of Th2
Thymic stromal lymphopoietin and IL-33 (zeige IL33 Antikörper) promote skin inflammation and vaccinia virus replication in a mouse model of atopic dermatitis.
the pathological mechanisms of particulate matter PM2.5 may be associated with allergic/steroidresistant airway inflammation, Tcell helper (Th)1 (zeige TH1L Antikörper)/Th2 cytokine production and upregulation of TSLP expression in a murine model of allergic and steroid-resistant asthma.
These findings suggest miR (zeige MLXIP Antikörper)-19b reduces airway remodeling, airway inflammation, and degree of oxidative stress by inhibiting Stat3 (zeige STAT3 Antikörper) signaling through TSLP downregulation in a mouse asthma model.
Results suggest combinatorial mechanisms involved in the tissue-selective regulation of thymic stromal lymphopoietin (TSLP) transcription in epidermal keratinocytes and intestinal epithelial cell(s) (IEC).
these results suggest that TSLP-TSLPR (zeige CRLF2 Antikörper) signaling is pivotal in the induction of nasal respiratory immunity against pathogenic pneumococcal infection
blockading the JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) pathway restrains inflammatory Th2 cell response induced by TSLP-DCs in allergic rhinitis.
study concludes that IL-33 (zeige IL33 Antikörper) and TSLP are required for epithelial cell IL-25 (zeige IL25 Antikörper) expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection
TSLP plays a role in dysfunction of airway epithelial adherens junctions E-cadherin (zeige CDH1 Antikörper) in house dust mite (HDM (zeige HDAC3 Antikörper))-induced asthma. Mice treated with an anti-TSLP mAb ameliorated airway inflammation, the decreasing and aberrant distribution of E-cadherin (zeige CDH1 Antikörper) and beta-catenin (zeige CTNNB1 Antikörper) as well as phosphorylation(p)-AKT (zeige AKT1 Antikörper) induced by HDM (zeige HDAC3 Antikörper). In vitro, HDM (zeige HDAC3 Antikörper) increased the expression of TSLP and E-cadherin (zeige CDH1 Antikörper) dysfunction by PI3K/Akt (zeige AKT1 Antikörper) signaling pathway.
this study shows that TSLP is a key target of Mi-2beta (zeige CHD4 Antikörper) in keratinocytes, and that loss of TSLP signaling in regulatory T cells prevents their activation
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
thymic stromal lymphopoietin
, thymic stromal lymphopoetin
, thymic stroma-derived lymphopoietin