anti-Thymic Stromal Lymphopoietin (TSLP) Antikörper

TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. Zusätzlich bieten wir Ihnen Thymic Stromal Lymphopoietin Kits (90) und Thymic Stromal Lymphopoietin Proteine (47) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TSLP 85480 Q969D9
TSLP 53603 Q9JIE6
TSLP 688621  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Thymic Stromal Lymphopoietin Antikörper auf antikoerper-online.de

Showing 10 out of 185 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Western blot analysis of TSLP in A-20 cell lysate with TSLP antibody at (A) 0.5, (B) 1 and (C) 2 ?g/ml. Immunohistochemistry: TSLP Antibody [ABIN2583904] - Immunohistochemistry of TSLP in human brain tissue with TSLP antibody at 2.5 ug/mL. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$446.35
Details
Hund Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert CC, WB Western blot analysis of TSLP using anti-TSLP antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: human Hela whole cell lysates, Lane 2: mouse spleen tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-TSLP antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4℃, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for TSLP at approximately 18KD. The expected band size for TSLP is at 18KD. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with TSLP antibody ABIN461900 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with TSLP antibody ABIN461900 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of TSLP using anti-TSLP antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: mouse liver tissue lysates,  Lane 2: mouse kidney tissue lysates, Lane 3: mouse testis tissue lysates, Lane 4: rat heart tissue lysates, Lane 5: rat liver tissue lysates, Lane 6: rat kidney tissue lysates, Lane 7: rat testis tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-TSLP antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for TSLP at approximately 18KD. The expected band size for TSLP is at 18KD. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Ziege Unkonjugiert ELISA (Capture), WB 100 μg Anmelden zum Anzeigen 10 bis 12 Tage
$263.22
Details
Human Kaninchen Unkonjugiert EIA, WB TSLP Antibody (C-term) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the TSLP antibody detected the TSLP protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, ELISA, WB Western blot analysis of TSLP in Jurkat cell lysate with TSLP antibody at (A) 1 and (B) 2 ?g/ml. Immunohistochemistry-Paraffin: TSLP Antibody [ABIN2583893] - Immunohistochemistry of TSLP in human brain tissue with TSLP antibody at 2.5 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Human Ziege Biotin ELISA (Detection) 50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$263.22
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$493.17
Details

Am meisten referenzierte anti-Thymic Stromal Lymphopoietin Antikörper

  1. Human Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN258390 : Levin, Koelling, Friend, Isaksen, Ziegler, Perlmutter, Farr: Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal TSLP Primary Antibody für IHC (p), IHC - ABIN5563670 : Quentmeier, Drexler, Fleckenstein, Zaborski, Armstrong, Sims, Lyman: Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. in Leukemia 2001 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal TSLP Primary Antibody für IHC (p), WB - ABIN541782 : Sims, Williams, Morrissey, Garka, Foxworthe, Price, Friend, Farr, Bedell, Jenkins, Copeland, Grabstein, Paxton: Molecular cloning and biological characterization of a novel murine lymphoid growth factor. in The Journal of experimental medicine 2000 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal TSLP Primary Antibody für IHC (p), ELISA - ABIN2476988 : Liu, Soumelis, Watanabe, Ito, Wang, Malefyt, Omori, Zhou, Ziegler: TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. in Annual review of immunology 2007 (PubMed)

  5. Mouse (Murine) Polyclonal TSLP Primary Antibody für ELISA, ICC - ABIN4363149 : Caglayan Sozmen, Karaman, Cilaker Micili, Isik, Arikan Ayyildiz, Bagriyanik, Uzuner, Karaman: Resveratrol ameliorates 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesions through effects on the epithelium. in PeerJ 2016 (PubMed)

  6. Human Polyclonal TSLP Primary Antibody für IF (p), IHC (p) - ABIN668766 : Sakitani, Nonaka, Shibata, Furukawa, Yoshihara: Increased Expression of Thymic Stromal Lymphopoietin and Its Receptor in Kimura's Disease. in ORL; journal for oto-rhino-laryngology and its related specialties 2015 (PubMed)

Weitere Antikörper gegen Thymic Stromal Lymphopoietin Interaktionspartner

Human Thymic Stromal Lymphopoietin (TSLP) Interaktionspartner

  1. TSLP receptor allosterically activates TSLP to potentiate the recruitment of the shared interleukin 7 receptor alpha-chain (IL-7Ralpha) by leveraging the flexibility, conformational heterogeneity and electrostatics of the cytokine.

  2. Effects of Linalyl Acetate on Thymic Stromal Lymphopoietin Production in Mast Cells.

  3. presence of epithelium-derived TSLP in the eustachian tubes plays important role in the onset of eosinophilic otitis media

  4. a new mechanism of T cell stimulation in human skin was identified, demonstrating the direct induction of T cell migration by TSLP in the absence of DCs.

  5. the secretion of TSLP by keratinocytes is induced by the HIV-1 viral synapse in a miR-375 controlled manner

  6. production increased at skin sites of ovalbumin sensitization

  7. Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels.

  8. short and long thymic stromal lymphopoietin isoforms have roles in house dust mite-induced asthmatic airway epithelial barrier disruption

  9. DeltaNp73 was abundantly expressed in the atopic dermatitis epidermis and increased the release of TSLP via NF-kappaB activation.

  10. this study shows that long form of thymic stromal lymphopoietin of keratinocytes is induced by protein allergens

  11. we found that activation of the protease-activated receptor 1 (PAR1) induced secretion of TSLP by the corneal stromal cells... we proposed that TSLP might function as the link between increased protease activity and inflammatory responses or itch sensation in the corneas

  12. TSLP-HOTAIR axis also plays a protective role in low-density lipoprotein (ox-LDL)-induced Endothelial cells' injury.

  13. The aim of this study was to determine the influence of human rhinovirus on the genes involved in airway remodeling and to examine the impact of TSLP and contribution of oxidative stress on airway remodeling in the context of HRV infection.

  14. TSLP-induced phosphorylation of l-plastin is increased in atopic dermatitis and increases eosinophil migration.

  15. a hit expansion exercise yielded additional active compounds that could be amenable to further optimization, providing an opportunity to dissociate TSLP inhibition from other non-desired activities. This study illustrates the potential of phenotypic drug discovery to complement target based approaches by providing new chemistry and biology leads

  16. study found that among patients with atopic dermatitis (AD), common FLG null mutations are associated with earlier AD onset in a dose-dependent manner, whereas TSLP rs1898671 appears unrelated to the timing of AD onset

  17. lactobacilli from the omnivorous group and all bifidobacteria significantly down-regulated IL-8. Notably, both genera also lowered the TSLP expression in stimulated Caco-2 cells, regardless of the diet regimen.

  18. this review focuses on recent advances on the effects of TSLP on obstetrical and gynecological diseases, including pregnancy failure, endometriosis, and cervical cancer

  19. The increase in TSLP and TNF-alpha level observed in IS fluid was found to correlate with disease severity. The increased TSLP production from asthma sputum cells was abrogated by the addition of rIL-37. Regulation of TSLP pathway may be a therapeutic approach for asthma.

  20. House dust mite sublingual immunotherapy downregulated Th2-type immune responses mediated by the TSLP-OX40L signaling pathway in patients with persistent moderate to severe allergic rhinitis.

Mouse (Murine) Thymic Stromal Lymphopoietin (TSLP) Interaktionspartner

  1. this paper shows that IL-33 promotes gastrointestinal allergy in a TSLP-independent manner

  2. a new pathway for the activation of Treg involving in tumor-derived HMGB1 and TSLP, and have important implications for incorporating HMGB1 inhibitors into cancer immunotherapy.

  3. Effects of Linalyl Acetate on Thymic Stromal Lymphopoietin Production in Mast Cells.

  4. findings suggest a role of TSLP in directly promoting Th2 cell effector function and support the notion of TSLP as a key driver of Th2

  5. Thymic stromal lymphopoietin and IL-33 promote skin inflammation and vaccinia virus replication in a mouse model of atopic dermatitis.

  6. the pathological mechanisms of particulate matter PM2.5 may be associated with allergic/steroidresistant airway inflammation, Tcell helper (Th)1/Th2 cytokine production and upregulation of TSLP expression in a murine model of allergic and steroid-resistant asthma.

  7. These findings suggest miR-19b reduces airway remodeling, airway inflammation, and degree of oxidative stress by inhibiting Stat3 signaling through TSLP downregulation in a mouse asthma model.

  8. Results suggest combinatorial mechanisms involved in the tissue-selective regulation of thymic stromal lymphopoietin (TSLP) transcription in epidermal keratinocytes and intestinal epithelial cell(s) (IEC).

  9. these results suggest that TSLP-TSLPR signaling is pivotal in the induction of nasal respiratory immunity against pathogenic pneumococcal infection

  10. blockading the JAK/STAT pathway restrains inflammatory Th2 cell response induced by TSLP-DCs in allergic rhinitis.

  11. study concludes that IL-33 and TSLP are required for epithelial cell IL-25 expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection

  12. TSLP plays a role in dysfunction of airway epithelial adherens junctions E-cadherin in house dust mite (HDM)-induced asthma. Mice treated with an anti-TSLP mAb ameliorated airway inflammation, the decreasing and aberrant distribution of E-cadherin and beta-catenin as well as phosphorylation(p)-AKT induced by HDM. In vitro, HDM increased the expression of TSLP and E-cadherin dysfunction by PI3K/Akt signaling pathway.

  13. this study shows that TSLP is a key target of Mi-2beta in keratinocytes, and that loss of TSLP signaling in regulatory T cells prevents their activation

  14. These data demonstrate that multiple pathogenic strains of RSV induce IL-13-producing group 2 innate lymphoid cell proliferation and activation through a TSLP-dependent mechanism in a murine model and suggest the potential therapeutic targeting of TSLP during severe RSV infection.

  15. the effects of TSLP on myeloid cells are crucial in reducing the multiple organ failure that is associated with systemic inflammation.

  16. The inflammatory phenotype in barrier-defective skin is shaped by counterregulation between the TSLP/type 2 and IL-23/type 17 axes.

  17. this study shows that activation of primed TH2 cells occurs independently of group 2 innate lymphoid cells or their cytokines but that the effector function of both cell types was dependent on combinatorial exposure to IL-33, IL-25 and TSLP

  18. TNF-alpha and IL-1beta, which are partly produced by LPS-activated leukocytes, contribute to TSLP production via TLR4 activation in vivo.

  19. IL-33-ERK/JNK/p38/Egr-1/TSLP axis involved in allergic skin Th2 inflammation

  20. Suggest that TSLP may be involved in acute lung injury, and blockage of TSLP signaling using TSLPR-Ig improves ALI at least in part by regulation of dendritic cell functions.

Guinea Pig Thymic Stromal Lymphopoietin (TSLP) Interaktionspartner

  1. presence of epithelium-derived TSLP in the eustachian tubes plays important role in the onset of eosinophilic otitis media

Thymic Stromal Lymphopoietin (TSLP) Antigen-Profil

Protein Überblick

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit TSLP

  • thymic stromal lymphopoietin (TSLP) Antikörper
  • thymic stromal lymphopoietin (Tslp) Antikörper
  • TSLP Antikörper

Bezeichner auf Proteinebene für TSLP

thymic stromal lymphopoietin , thymic stromal lymphopoetin , thymic stroma-derived lymphopoietin

GENE ID SPEZIES
706194 Macaca mulatta
737202 Pan troglodytes
100302635 Equus caballus
85480 Homo sapiens
53603 Mus musculus
688621 Rattus norvegicus
101788673 Cavia porcellus
607671 Canis lupus familiaris
617637 Bos taurus
Ausgewählte Anbieter für anti-Thymic Stromal Lymphopoietin (TSLP) Antikörper
Haben Sie etwas anderes gesucht?