anti-Thrombomodulin (THBD) Antikörper

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. Zusätzlich bieten wir Ihnen Thrombomodulin Kits (104) und Thrombomodulin Proteine (32) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
THBD 7056 P07204
THBD 21824 P15306
THBD 83580  
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Top anti-Thrombomodulin Antikörper auf antikoerper-online.de

Showing 10 out of 300 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD141 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE antibody diluted at 1:500 IHC-P Image Thrombomodulin antibody [C3], C-term detects THBD protein at cytosol and membrane on human gastric cancer by immunohistochemical analysis. Sample: Paraffin-embedded gastric cancer. Thrombomodulin antibody [C3], C-term , dilution: 1:500. 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Maus Unkonjugiert IHC ABIN6383797 to THBD was successfully used to stain human cervical carcinoma and placenta sections. Recommended concentration: 1-3ug/ml; Formaldehyde-fixed, paraffin-embedded human placenta stained with THBD Recombinant Mouse Monoclonal Antibody ABIN6383797 at 1-2ug/ml for 30 minutes at RT. Epitope retrieval: Boiling at pH9 for 10-20 min followed by 20 min cooling. DAB staining by HRP polymer. ABIN6383797 to THBD was successfully used to stain human cervical carcinoma and placenta sections. Recommended concentration: 1-3ug/ml; 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$563.61
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from K562 cells, using THBD antibody. Western blot analysis of THBD expression in various lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Maus Ziege Unkonjugiert CyTOF, FACS, ICC, IP, WB Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse Thrombomodulin/BDCA-3 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.97
Details
Maus Ratte Unkonjugiert CyTOF, FACS, ICC, IHC, WB Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody. Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Rat IgG Secondary Antibody (red 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$299.45
Details
Human Maus FITC FACS 1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Maus Unkonjugiert FACS 2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$379.50
Details
Maus Ratte PE FACS Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse Thrombomodulin/BDCA-3 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$331.09
Details
Human Maus Unkonjugiert IHC, IHC (p) Anti-CD141 / Thrombomodulin antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. 250 μL Anmelden zum Anzeigen 11 bis 14 Tage
$771.83
Details

Am meisten referenzierte anti-Thrombomodulin Antikörper

  1. Human Polyclonal Thrombomodulin Primary Antibody für WB - ABIN2801892 : Suzuki, Kusumoto, Deyashiki, Nishioka, Maruyama, Zushi, Kawahara, Honda, Yamamoto, Horiguchi: Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. in The EMBO journal 1987 (PubMed)
    Show all 5 Pubmed References

  2. Mouse (Murine) Polyclonal Thrombomodulin Primary Antibody für CyTOF, FACS - ABIN4899312 : Schmidt, Yang, Janssen, Gandjeva, Perez, Barthel, Zemans, Bowman, Koyanagi, Yunt, Smith, Cheng, Overdier, Thompson, Geraci, Douglas, Pearse, Tuder: The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. in Nature medicine 2013 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal Thrombomodulin Primary Antibody für FACS, WB - ABIN2192010 : Dömötör, Benzakour, Griffin, Yule, Fukudome, Zlokovic: Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. in Blood 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal Thrombomodulin Primary Antibody für WB - ABIN2192009 : Tsuneyoshi, Fukudome, Higuchi, Kimoto: Preparation and characterization of monoclonal antibodies to thrombomodulin. in Hybridoma (2005) 2005 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal Thrombomodulin Primary Antibody für IHC (fro), FACS - ABIN2478498 : Drake, Loke: Isolation of endothelial cells from human first trimester decidua using immunomagnetic beads. in Human reproduction (Oxford, England) 1992 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody für CyTOF, FACS - ABIN4899313 : Belcher, Chen, Nguyen, Milbauer, Abdulla, Alayash, Smith, Nath, Hebbel, Vercellotti: Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. in Blood 2014 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal Thrombomodulin Primary Antibody für FM, IHC (fro) - ABIN2688974 : Teasdale, Bird, Bird: Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain. in Immunology and cell biology 1995 (PubMed)

  8. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody für FACS - ABIN4895906 : Geiger, Pawar, Kerschen, Nattamai, Hernandez, Liang, Fernández, Cancelas, Ryan, Kustikova, Schambach, Fu, Wang, Fink, Petersen, Zhou, Griffin, Baum, Weiler, Hauer-Jensen: Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. in Nature medicine 2012 (PubMed)

Weitere Antikörper gegen Thrombomodulin Interaktionspartner

Human Thrombomodulin (THBD) Interaktionspartner

  1. Thrombomodulin gene C1418T polymorphism is associated with Kawasaki disease.

  2. SETD1A contributes to retinoic acid -induced thrombomodulin expression in vascular endothelial cells by modulating the activity and expression of KLF4.

  3. we for the first time demonstrated that TM binds to GPR15 via its EGF-like domain and exerts angiogenesis and cytoprotective function in vascular ECs.

  4. Bioinformatics analysis and screening of controls strongly suggested that the THBD-p.Trp153Gly mutation might be related to RPL aetiology.

  5. Taken together, our findings suggest that TM-PKCdelta interaction may contribute to cardiovascular disorders by affecting monocye differentiation, which may develop future therapeutic applications.

  6. A heterozygous variant displaying autosomal dominant inheritance (c.1611 C>A) was found in the gene THBD which encodes the glycoprotein thrombomodulin. This sequence change results in a stop codon (p.Cys537Stop) and truncation of the protein

  7. Lys 42, Lys 43, Lys 44 and Arg 12 are critical for the interaction of TAFI with the thrombin-thrombomodulin complex, which modulates its antifibrinolytic potential.

  8. Ligation of anti-HLA class I and II antibodies produces different effects on the endothelial expression of TBM and on serum levels of TBM in transplant recipients.

  9. Fibrinogen gamma acts as thrombomodulin II. (Review)

  10. Thrombomodulin (TM) promotes angiogenesis by enhancing cell adhesion, migration, and FAK activation through interaction with fibronectin.

  11. The elevation of serum thrombomodulin (sTM)level suggests that endothelial damage occurs in Abdominal Aortic Aneurysm pathogenesis.

  12. This population-based cohort study within the ARIC study did not replicate the Hernandez et al. finding that carrying the minor allele of 3 THBD SNPs doubles the risk of venous thromboembolism in African Americans. In fact, the HRs of VTE among carriers of the minor allele were <1. HRs were similar for white subjects. A strand-flip did not explain the discrepancies.

  13. these results suggest a novel function for thrombomodulin as an adhesion molecule in monocytes, where it enhances cell adhesion by binding Ley, leading to beta2 integrin activation via p38 MAPK

  14. TM, especially TME45, maintains vascular integrity, at least in part, via Src signaling.

  15. The present study found that the fifth epidermal growth factor-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C-independent

  16. Case Report: CD141+ myeloid dentritic cell differentiation of a juvenile myelomonocytic leukemia.

  17. the effect of thromobomodulin c.1418C > T polymorphism on the pathogenesis of venous thrombosis

  18. The finding of a previously unrecognized fibrinolytic phenotype indicates that bleeding in Thrombomodulin-associated coagulopathy has a complex pathogenesis and highlights the pivotal role of TM as a regulator of hemostasis.

  19. TM mediates cell proliferation and migration via the Epithelial-To-Mesenchymal Transition (EMT) biomarkercyclooxygenase (COX)-2

  20. the whole THBD gene sequenced in patients with recurrent venous thromboembolism (VTE); found 8 polymorphisms in the THBD gene in Swedish population; none of these polymorphisms was significantly associated with the risk of VTE recurrence; results indicate that THBD polymorphisms may not be a risk factor for VTE recurrence

Mouse (Murine) Thrombomodulin (THBD) Interaktionspartner

  1. macrophage infiltration and neointima formation following arterial ligation-induced vascular injury were higher in wild-type than in myeloid-specific thrombomodulin-deficient mice

  2. discovery of a novel physiological function of thrombomodulin-dependent activated protein C generation within the CNS

  3. The present study found that the fifth epidermal growth factor-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C-independent

  4. the lectin-like domain of thrombomodulin is critically involved in host defence against E. coli induced acute pyelonephritis

  5. Identified Nur77/Nor1 as novel regulators of thrombomodulin expression and function in vascular endothelial cells.

  6. TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF-BB. In addition, rTMD23 has therapeutic potential in corneal injury

  7. Membrane-bound TM in macrophages plays an essential role in the development of abdominal aortic aneurysms by enhancing proinflammatory mediator elaboration, macrophage recruitment, and oxidative stress.

  8. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice

  9. the recombinant epidermal growth factor-like domain plus serine/threonine-rich domain of thrombomodulin suppresses the inflammatory response in mice

  10. Thrombomodulin may modulate allergic responses by inhibiting the activation of both eosinophils and mast cells.

  11. Thrombomodulin modulates dendritic cells via both antagonism of high mobility group protein B1 and an independent mechanism.

  12. The lectin-like domain of TM does not play an important role in the host response to M. tuberculosis infection in mice.

  13. Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.

  14. TM has a critical role in skin differentiation and wound healing.

  15. TM's lectin-like domain constrains glucose-induced complement activation on endothelial cells and podocytes and ameliorates albuminuria and glomerular damage.

  16. FFAs inhibit TM-EPCR-Protein C system in endothelial cells through activating JNK signaling, which may be a mechanism for the prothrombotic state in metabolic syndrome.

  17. Genetic or acquired thrombomodulin defects might have an impact on the severity of microangiopathic lesions after exposure to Shiga toxin-producing E. coli infections.

  18. we conclude that monocytic membrane-bound thrombomodulin participates in the LPS- and gram-negative bacteria-induced inflammatory response.

  19. Recombinant thrombomodulin domains 2 and 3 protein significantly reduces atherosclerosis and neointima formation through its thrombin-binding ability.

  20. RHBDL2 and soluble thrombomodulin were upregulated in ex vivo tissue culture of injured mouse skin. 3,4-Dichloroisocoumarin inhibited thrombomodulin production and wound healing; this was reversed by recombinant thrombomodulin in mice.

Rabbit Thrombomodulin (THBD) Interaktionspartner

  1. Atorvastin induces THBD expression in the aorta of cholesterol-fed rabbits.

Thrombomodulin (THBD) Antigen-Profil

Protein Überblick

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Genbezeichner und Symbole assoziert mit anti-Thrombomodulin (THBD) Antikörper

  • thrombomodulin (THBD) Antikörper
  • thrombomodulin (Thbd) Antikörper
  • AHUS6 Antikörper
  • AI385582 Antikörper
  • BDCA3 Antikörper
  • CD141 Antikörper
  • THBD Antikörper
  • THPH12 Antikörper
  • THRM Antikörper
  • TM Antikörper

Bezeichner auf Proteinebene für anti-Thrombomodulin (THBD) Antikörper

thrombomodulin , CD141 antigen , fetomodulin , snoRNA MBII-339 , thrombomdulin , TM

GENE ID SPEZIES
469898 Pan troglodytes
702132 Macaca mulatta
100049012 Felis catus
7056 Homo sapiens
474355 Canis lupus familiaris
21824 Mus musculus
83580 Rattus norvegicus
100157642 Sus scrofa
100008887 Oryctolagus cuniculus
100723479 Cavia porcellus
281529 Bos taurus
428546 Gallus gallus
101103256 Ovis aries
Ausgewählte Anbieter für anti-Thrombomodulin (THBD) Antikörper
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