TYRO Protein tyrosine Kinase Binding Protein (TYROBP) ELISA Kits

TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. Zusätzlich bieten wir Ihnen TYROBP Antikörper (101) und TYROBP Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TYROBP 361537 Q6X9T7
TYROBP 7305 O43914
TYROBP 22177 O54885
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Showing 5 out of 14 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Maus 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für TYROBP Interaktionspartner

Zebrafish TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. The structure of the adaptor protein dap12 has been identified in the zebrafish genome.

  2. DAP12-based activating pathway is conserved between bony fish and mammals

Human TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. Mutations in TYROBP are not a common cause of dementia in this Turkish cohort.

  2. Rare TYROBP variants might contribute to early-onset Alzheimer's disease risk by reduction of TREM2 (zeige TREM2 ELISA Kits) expression, a well-established risk factor for AD.

  3. TYROBP influences a batch of genes that are related to Alzheimer's disease; ZNF329 and RB1 (zeige RB1 ELISA Kits) significantly regulate those 'mesenchymal' gene expression signature genes for brain tumors. By merely leveraging gene expression data, Context Based Dependency Network (CBDN) can efficiently infer the existence of gene-gene interactions as well as their regulatory directions.

  4. TYROBP/CSTA gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis

  5. The different expression of DAP12 compared to TREM2 (zeige TREM2 ELISA Kits) represents the first description of such variable expressivity in Nasu-Hakola disease (NHD) microglia.

  6. the microglial membrane adaptor protein DAP12 was required for both nerve injury- and intrathecal CSF1 (zeige CSF1 ELISA Kits)-induced upregulation of pain-related microglial genes and the ensuing pain, but not for microglial proliferation

  7. Impaired signaling by the TREM2 (zeige TREM2 ELISA Kits)-DAP12 pathway leads to altered immune responses in phagocytosis, cytokine production, and microglial proliferation and survival, thus contributing to disease pathogenesis. Review.

  8. T cells modified to express a KIR (zeige GEM ELISA Kits)-CAR and DAP12 exhibit superior antitumor activity compared with standard first- and second-generation CD3zeta (zeige CD247 ELISA Kits)-based CARs in a xenograft model of mesothelioma highly resistant to immunotherapy.

  9. This study reveled that TYROBP having a central role in the bipolar disease and schizophrenia manifestation.

  10. isolated PMNs have an increased proportion of both TREM1 (zeige TREM1 ELISA Kits) and DAP12 compared to normal healthy control

Mouse (Murine) TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. We identified modulatory effects of TYROBP deficiency on the level of phosphorylation of TAU that was accompanied by a reduction in the severity of neuritic dystrophy. TYROBP deficiency also altered the expression of several AD related genes, including Cd33 (zeige CD33 ELISA Kits). Electrophysiological abnormalities and learning behavior deficits associated with APP (zeige APP ELISA Kits)/PSEN1 (zeige PSEN1 ELISA Kits) transgenes were greatly attenuated on a Tyrobp-null background.

  2. These results demonstrate that PTX targets the innate immunity through DAP12, FcRgamma, and MyD88 providing new insights into the immunobiology of PTX.

  3. Recent studies have revealed that activated microglia in the spinal dorsal horn exacerbate neuropathic pain, which has suggested that suppression of microglial activity should be considered as a therapeutic target. However, only a few molecules have been identified as regulators of microglial activity. In this study, we focused on a receptor complex of TREM2 (zeige TREM2 ELISA Kits) and DAP12, both of which are expressed by microglia and have bee

  4. TNF (zeige TNF ELISA Kits)/IL-6 (zeige IL6 ELISA Kits) generated osteoclasts in vitro that resorbed mineralized tissue through a pathway dependent on IL-6R, NFATc1 (zeige NFATC1 ELISA Kits), DNAX-activation protein 12, and cell proliferation.

  5. The findings suggest that DAP12 acts as a brake on the pulmonary immune response to C. neoformans by promoting pulmonary eosinophilia and by inhibiting the activation and antifungal activities of effector cells, including NK cells and macrophages.

  6. significant role of DAP12 in the initial inflammatory response, bone remodeling and regeneration

  7. DAP12-mediated microglial activation following axotomy promotes pro-inflammatory responses, and thereby accelerates nerve injury-induced neuron death

  8. results support a role of DAP12 in stabilizing TREM2 (zeige TREM2 ELISA Kits)-CTF (zeige NFIA ELISA Kits), thereby protecting against excessive pro-inflammatory responses.

  9. a previously unrecognized role for DAP12 expression in tissue-resident alveolar macrophages in mediating acute noninfectious tissue injury through regulation of neutrophil trafficking.

  10. DAP12 expression in liver grafts regulates donor mDC (zeige ADAM11 ELISA Kits) migration to host lymphoid tissue, alloreactive T cell responses and transplant tolerance

Cow (Bovine) TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

TYROBP Antigen-Profil

Beschreibung des Gens

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit TYROBP

  • TYRO protein tyrosine kinase binding protein (TYROBP) Antikörper
  • TYRO protein tyrosine kinase binding protein (tyrobp) Antikörper
  • Tyro protein tyrosine kinase binding protein (Tyrobp) Antikörper
  • TYRO protein tyrosine kinase binding protein (Tyrobp) Antikörper
  • dap12 Antikörper
  • KARAP Antikörper
  • Ly83 Antikörper
  • PLOSL Antikörper
  • TYROBP Antikörper
  • tyrpbp Antikörper

Bezeichner auf Proteinebene für TYROBP

TYRO protein tyrosine kinase-binding protein , TYRO protein tyrosine kinase binding protein , DAP12 protein , dap12 , DAP12 , DNAX-activation protein 12 , killer cell activating receptor-associated protein , KAR-associated protein , killer activating receptor associated protein , killer-activating receptor-associated protein , killer cell activating receptor associated protein , immunoreceptor DAP12 , tyrosine kinase binding protein

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100101461 Danio rerio
361537 Rattus norvegicus
7305 Homo sapiens
22177 Mus musculus
282390 Bos taurus
397405 Sus scrofa
574207 Macaca mulatta
455968 Pan troglodytes
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