TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA Kits

TIMP3 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP3 Antikörper (199) und TIMP3 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TIMP3 7078 P35625
TIMP3 25358  
TIMP3 21859 P39876
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Top TIMP3 ELISA Kits auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Ratte 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Maus 0.069 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Rind (Kuh) 0.119 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage
Huhn 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Kaninchen 0.131 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage
Schwein 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Pferd 0.115 ng/mL 0.31 ng/mL - 20 ng/mL Typical Standard Curve for Equine TIMP3 ELISA. 96 Tests 13 bis 16 Tage
Ziege 0.122 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage
Rhesusaffen 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage

Am meisten referenzierte TIMP3 ELISA Kits

  1. Human TIMP3 ELISA Kit für Sandwich ELISA - ABIN414926 : Li, Liang, Tao, Zhou, Li, Chen, Chen: Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells. in Experimental biology and medicine (Maywood, N.J.) 2012 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) TIMP3 ELISA Kit für Sandwich ELISA - ABIN415606 : Shukla, Kumar Shakya, Dhole, Misra: Upregulated expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in BALB/c mouse brain challenged with Japanese encephalitis virus. in Neuroimmunomodulation 2012 (PubMed)
    Show all 2 Pubmed References

  3. Rat (Rattus) TIMP3 ELISA Kit für Sandwich ELISA - ABIN416332 : Kna?, Niczyporuk, Zalewska, Car: The unwounded skin remodeling in animal models of diabetes types 1 and 2. in Physiological research / Academia Scientiarum Bohemoslovaca 2013 (PubMed)
    Show all 2 Pubmed References

  4. Rat (Rattus) TIMP3 ELISA Kit für Sandwich ELISA - ABIN5525169 : Balbaa, El-Zeftawy, Ghareeb, Taha, Mandour: Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet. in Oxidative medicine and cellular longevity 2017 (PubMed)

Weitere ELISA Kits für TIMP3 Interaktionspartner

Human TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. IL-32gamma may increase TIMP-3 expression via hypomethylation through inactivation of NF-kappaB activity, and thereby reduce lung tumor growth.

  2. TIMP-3-overexpression in HEK293 cells demonstrated that TIMP-3 had a dual effect leading to a) inhibited shedding of several transmembrane proteins, in particular substrates of ADAM10, suggesting that exogenous TIMP-3 preferentially inhibits ADAM10 in HEK293 cells and b) increased levels of several LRP-1 ligands, likely by competing for their binding to LRP-1 and their subsequent internalization.

  3. the present study demonstrated the regulatory contribution of SNHG16/miR-17-5p/TIMP3 axis to viability, apoptosis, proliferation, and epithelial-mesenchymal transition of bladder cancer cells, which directly affected tumor progression.

  4. The presence of CpG islands hemimethylation in tissue inhibitor of metalloproteinases 3 and O-6-methylguanine-DNA methyltransferase genes is a promising triage method in cervical intraepithelial neoplasia recurrence.

  5. This study demonstrated that miR-191 promoted the cell growth and invasion ability in prostate cancer through downregulating TIMP3 and might be a potential target for the biotherapy for Prostate cancer (PCa).

  6. our results suggest that TIMP3 reversely mediates UVR-induced inflammation by being highly expressed during the daytime; therefore, recovering the circadian expression of TIMP3 using synthetic TIMP3 peptides or bioactive natural ingredients could at least in part inhibit the UVR-induced cellular phenomena.

  7. In aortic valves, disturbed flow leads to downregulation of TIMP3 via mechanosensitive microRNA-181b and results in endothelial matrix degradation.

  8. ADAMTS-2, collagen type-1, TIMP-3 and papilin levels of the uterosacral ligament play essential roles in the etiopathogenesis of pelvic organ prolapse among postmenopausal women without stress urinary incontinence.

  9. The down-regulation of miR-21 inhibited the progression of diabetic nephropathy by targeting TIMP3.

  10. we have shown that deleterious variation in TIMP3 is associated with bicuspid aortic valve and indices of thoracic aortic aneurysm. We further found that there is a synergistic interaction between loss of the X chromosome gene, TIMP1, and deleterious variation in TIMP3 that significantly increases that risk.

  11. MiR-21 was up-regulated in cervical cancer tissues and serum samples, in contrast, TIMP3 was down-regulated in cervical cancer tissues. MiR-21 promoted the proliferation, viability and the migratory and invasive activities of cervical cancer cells through targeting TIMP3. Overexpression of TIMP3 attenuated the positive effects of miR-21.

  12. Both combinations were able to increase the expressions of p53, TIMP-3 proteins, and MiR-34a in the HeLa cells.

  13. these results demonstrate that decreased TIMP-3 expression may contribute to cisplatin resistance via inhibition of mitochondria-dependent apoptosis, indicating that forced TIMP-3 expression may be a useful strategy to improve the efficacy of cisplatin to treat laryngeal carcinoma

  14. Genetic variation in the TIMP-3 gene may contribute to individual differences in mixture plaque susceptibility in the Han Chinese population.

  15. TIMP3 methylation is a marker for TN tumours and furthermore we showed for the first time that TIMP3 promoter methylation is an epigenetic marker of BRCA1ness tumours.

  16. As a novel CLOCK-dependent diurnal gene, TIMP3 inhibits the expression of inflammatory cytokines that are up-regulated by UV irradiation in human keratinocytes.

  17. miR-21-5p mediates apoptosis by targeting PTEN and TIMP3.

  18. Preliminary studies indicate that baseline MMP3 and TIMP3 concentrations are associated with patient survival and disease-free time

  19. TIMP-3 mRNA expression levels positively correlates with levels of miR-21 in in situ breast carcinomas and negatively in progesterone receptor positive invasive breast carcinomas.

  20. Sphingosine-1-phosphate inhibited cell migration and MMP-2 expression through the upregulation of the tissue inhibitor of metalloproteinase-3 (TIMP-3) expression in human chondrosarcoma cells.

Rabbit TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. The present study demonstrated the ability of 30 and 100 ng/ml TIMP3 to attenuate migration and proliferation, and to inhibit the activity of MMP2, MMP9 and TNFalpha secretion of NA SMCs. In conclusion, TIMP3 may be considered a potential therapeutic drug for use in a novel drugeluting stent, to attenuate the progressive dilation of the aortic NA.

  2. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 secretion.

  3. TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased MMP-14.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. Reactive oxygen species mediate TGF-beta1-induced TIMP-3 gene expression

  2. TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.

  3. TIMP3 mRNA expression level was upregulated by multidirectional articular motion.

Xenopus laevis TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. only the N-terminal, but not the C-terminal domain of TIMP-3, results in developmental defects.

  2. metamorphic tail and intestine RNA levels of TIMP-2, MT1-MMP and Gel-A, but not MT3-MMP or TIMP-3, are elevated during periods of cell death and proliferation

Mouse (Murine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. the absence of TIMP-3 leads to a more pro-angiogenic microenvironment, playing a key role in choroidal neovascularization formation by positively modulating M2 polarization.

  2. the aim of this study was to determine whether Acanthamoeba spp. may affect the levels of matrix metalloproteinases (MMP-2,-9), their tissue inhibitors (TIMP-1,-3) and MMP-9/TIMP-1, MMP-2/TIMP-3 ratios in the cerebral cortex and hippocampus, in relation to the host's immunological status.

  3. The data indicate that hepatic TIMP3 expression can slow the progression of nonalcoholic fatty liver disease and tumorigenesis, at least in part, through the regulation of ADAM17 activity.

  4. Loss of Timp3 enhanced the susceptibility to iron overload-mediated heart and liver injury, suggesting that Timp3 is a key protective molecule against iron-mediated pathology.

  5. Loss of TIMP3 is associated with germinal matrix hemorrhage-intraventricular hemorrhage.

  6. altered cortical and trabecular bone mineralization and increased compositional heterogeneity were found in Timp-3 (-/-) bone, all being indicative of high bone remodeling

  7. In a clinically relevant CADASIL mouse model, we show that exogenous ADAM17 or HB-EGF restores cerebral arterial tone and blood flow responses, and identify upregulated voltage-dependent potassium channel (KV) number in cerebral arterial myocytes as a heretofore-unrecognized downstream effector of TIMP3-induced deficits.

  8. TIMP3 promotes normal microvascular endothelial cell barrier function, at least partially, through inhibition of metalloproteinase-dependent disruption of adherens junctions, and septic downregulation of TIMP3 may contribute to septic MVEC barrier dysfunction.

  9. data strongly suggest that TIMP3 has direct neuroprotective effects that can mitigate the deleterious effects associated with TBI, an area with few if any therapeutic options.

  10. Elevated levels of TIMP3 and vitronectin, acting downstream of Notch3(ECD) deposition, play a role in CADASIL, producing divergent influences on early CBF deficits and later white matter lesions.

  11. 4-Hydroxyisoleucine improved insulin resistant-like state in 3T3-L1 adipocytes by targeting TACE/TIMP3 and the insulin signaling pathway.

  12. In a mouse model of prostate cancer, increased tumor growth, proliferation index, increased microvascular density, and invasion was observed in Pten(-/-), Timp3(-/-) prostate tumors compared to Pten(-/-), Timp3(+/+) tumors.

  13. Timp3 status determines p53, p38 and Notch coactivation to instruct hepatic cell fate and transformation.

  14. TIMP2 and TIMP3 play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function

  15. Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3-deficient mice.

  16. lack of TIMP3 increases inflammation and polarizes macrophages towards a more inflammatory phenotype resulting in increased atherosclerosis.

  17. TIMP-3 KO mice exhibit enhanced metabolism, as reflected by a higher body temperature than WT mice, possibly due to increased mitochondrial activity.

  18. TIMP3 protects kidney from damage

  19. TIMP3 reduction is due, at least in part, to increased expression of certain TIMP3-targeting microRNAs in diabetic kidneys compared to healthy controls.

  20. Demonstrate a critical role for TIMP3, among all TIMPs, in preserving arterial remodelling in response to Ang II-induced hypertension.

Pig (Porcine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) Interaktionspartner

  1. miR-21 promotes cumulus expansion and oocyte maturation via down-regulating TIMP3

  2. These results suggest the crucial role of TIMP-3 in successful implantation and embryo survival and indicate the endometrial stromal decidualization-like in pigs.

TIMP3 Antigen-Profil

Beschreibung des Gens

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Genbezeichner und Symbole assoziert mit TIMP3

  • metalloproteinase inhibitor 3 (CpipJ_CPIJ003282) Antikörper
  • TIMP metallopeptidase inhibitor 3 (TIMP3) Antikörper
  • Metalloproteinase inhibitor 3 (timp3) Antikörper
  • TIMP metallopeptidase inhibitor 3 (Timp3) Antikörper
  • TIMP metallopeptidase inhibitor 3 L homeolog (timp3.L) Antikörper
  • tissue inhibitor of metalloproteinase 3 (Timp3) Antikörper
  • HSMRK222 Antikörper
  • IMP-3 Antikörper
  • K222 Antikörper
  • K222TA2 Antikörper
  • SFD Antikörper
  • Timp-3 Antikörper
  • timp3 Antikörper
  • timp3-A Antikörper

Bezeichner auf Proteinebene für TIMP3

metalloproteinase inhibitor 3 , TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor metalloproteinase-3 , TIMP metallopeptidase inhibitor 3 , Metalloproteinase inhibitor 3 , MIG-5 protein , TIMP-3 , protein MIG-5 , tissue inhibitor of metalloproteinases 3 , tissue inhibitor of metalloproteinase-3 , tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor of metalloproteinase 3 , 21 kDa protein of extracellular matrix , tissue inhibitor of metalloproteinases-3

6034728 Culex quinquefasciatus
481289 Canis lupus familiaris
100135460 Papio anubis
100196821 Salmo salar
7078 Homo sapiens
100008690 Oryctolagus cuniculus
25358 Rattus norvegicus
282094 Bos taurus
100033947 Equus caballus
396483 Gallus gallus
373596 Xenopus laevis
574381 Macaca mulatta
100217407 Ovis aries
21859 Mus musculus
396775 Sus scrofa
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