anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) Antikörper

TIMP1 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP1 Kits (143) und TIMP1 Proteine (58) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIMP1 7076 P01033
TIMP1 116510 P30120
TIMP1 21857 P12032
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Top anti-TIMP1 Antikörper auf antikoerper-online.de

Showing 10 out of 307 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of TIMP1 Antibody (N-term) (ABIN390664) in CEM cell line lysates (35 µg/lane). TIMP1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcionma reacted with TIMP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of TIMP1 Antibody (C-term) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). TIMP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TIMP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus PE FACS Detection of TIMP-1 in NS0 Mouse Cell Line transfected with human TIMP-1 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human TIMP-1 was stained with Mouse Anti-Human TIMP-1 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$345.00
Details
Human Maus Unkonjugiert CyTOF, ELISA (Capture), FACS, IHC, WB TIMP-1 in Human Astrocytoma. TIMP-1 was detected in immersion fixed paraffin-embedded sections of human astrocytoma using Human TIMP-1 Monoclonal Antibody  at 15 µ 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$328.90
Details
Human Kaninchen Unkonjugiert EIA, WB Formalin-fixed and paraffin-embedded human breast carcionma reacted with TIMP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of TIMP1 Antibody (N-term) in CEM cell line lysates (35ug/lane). TIMP1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti-TIMP-1(NT) Polyclonal Antibody, Unconjugated (ABIN668331) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rabbit liver tissue labeled with Rabbit Anti-TIMP-1(NT) Polyclonal Antibody, Unconjugated (ABIN668331) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from rat brain cells, using TIMP1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunocytochemistry/Immunofluorescence: TIMP-1 Antibody (F31 P2 A5) [ABIN2616391] - Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes at room temperature and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a TIMP1 Monclonal Antibody (F31 P2 A5) at a dilution of 1:20 and incubated overnight in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody for 45 minutes at room temperature in the dark. F-actin (red) was stained with a fluorescent phalloidin and nuclei (blue) were stained with DAPI. Immunohistochemistry-Paraffin: TIMP-1 Antibody (F31 P2 A5) [ABIN2616391] - Normal biopsies of deparaffinized Human prostate tissue at a dilution of 1:20. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details

TIMP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-TIMP1 Antikörper

  1. Human Monoclonal TIMP1 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899801 : Li, Hou, Shao, Tang, Li: The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy. in Biology of reproduction 2010 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal TIMP1 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899800 : Naveau, Reinald, Fournier, Durand, Lafont, Coulomb, Gogly: Gingival fibroblasts inhibit MMP-1 and MMP-3 activities in an ex-vivo artery model. in Connective tissue research 2007 (PubMed)
    Show all 13 Pubmed References

  3. Mouse (Murine) Polyclonal TIMP1 Primary Antibody für WB - ABIN4886743 : Jiang, Han, Li, Yang, Liu: Carboxymethyl chitosan represses tumor angiogenesis in vitro and in vivo. in Carbohydrate polymers 2015 (PubMed)
    Show all 11 Pubmed References

  4. Human Polyclonal TIMP1 Primary Antibody für IHC (p), WB - ABIN3044394 : Xu, Ling, Zhu, Fan, Zhang: The effect of 2,3,4',5-tetrahydroxystilbene-2-0-?-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms. in European journal of pharmacology 2013 (PubMed)
    Show all 11 Pubmed References

  5. Human Polyclonal TIMP1 Primary Antibody für IF (cc), IF (p) - ABIN668331 : Sassoli, Nosi, Tani, Chellini, Mazzanti, Quercioli, Zecchi-Orlandini, Formigli: Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells. in Experimental cell research 2014 (PubMed)
    Show all 8 Pubmed References

  6. Cow (Bovine) Polyclonal TIMP1 Primary Antibody für IHC, ELISA - ABIN1582210 : Pitteri, Kelly-Spratt, Gurley, Kennedy, Buson, Chin, Wang, Zhang, Wong, Chodosh, Nelson, Hanash, Kemp: Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. in Cancer research 2011 (PubMed)
    Show all 6 Pubmed References

  7. Human Polyclonal TIMP1 Primary Antibody für IHC, IHC (p) - ABIN4359794 : Jurga, Piotrowska, Makuch, Przewlocka, Mika: Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model. in Frontiers in pharmacology 2017 (PubMed)

  8. Human Polyclonal TIMP1 Primary Antibody für ELISA, WB - ABIN4359793 : Ahn, Kim, Lee, Cho, Yoo, Kim, Ko, Kim: Generation of antibodies recognizing an aberrant glycoform of human tissue inhibitor of metalloproteinase-1 (TIMP-1) using decoy immunization and phage display. in Journal of biotechnology 2011 (PubMed)

  9. Human Monoclonal TIMP1 Primary Antibody für FACS - ABIN4896673 : Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005 (PubMed)

Weitere Antikörper gegen TIMP1 Interaktionspartner

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Our results provided evidence that polymorphisms in TIMP1, DLX1 and DLX2 genes may be associated with DF phenotypes.

  2. The plasma levels of interleukin (IL)-1beta (zeige IL1B Antikörper), tumor necrosis factor (TNF)-alpha (zeige TNF Antikörper), tissue inhibitor of metalloproteinases (TIMP)-1 are increased in myelofibrosis (MF) patients.

  3. The present study suggests that scoring of TIMP-1 immunoreactivity is a better choice than measuring of TIMP-1 plasma levels.

  4. Results show that TIMP1 expression is significantly upregulated in human colon cancer. Its suppression decreases proliferation, and metastasis but increases apoptosis by inducing TIMP1 specific regulated FAK (zeige PTK2 Antikörper)-PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) and MAPK (zeige MAPK1 Antikörper) pathway. These results suggest that TIMP1 may play an important role in promoting tumorigenesis and metastasis of human colon cancer.

  5. cancer associated fibroblasts (CAFs) promoted hepatocellular cancer (HCC) growth via IL-6/STAT3/AKT pathway and TIMP-1 over-expression driven by IL-6/STAT3 pathway in HCC cells brought in more CAFs through activating liver fibroblasts.

  6. Tissue inhibitor of matrix metalloproteinases 1 (TIMP1) inhibition resensitized tumors to gemcitabine and radiotherapy.

  7. Suggest that IL-6 (zeige IL6 Antikörper) could promote the invasiveness of breast cancer cells by inducing secretion of TIMP-1 and -2, causing a disturbance in TIMP/MMP balance.

  8. This study indicates that in our population, the COL4A3 (zeige COL4a3 Antikörper) rs55703767 polymorphism decreased the risk of KC. However, the TIMP-1 rs6609533 polymorphism was associated with an increased risk of KC.

  9. Low MMP-8 (zeige MMP8 Antikörper)/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome

  10. Data show that the mean values for TIMP1, TIMP2 (zeige TIMP2 Antikörper) and MMP2 (zeige MMP2 Antikörper) were lower in survivors, MMP9 (zeige MMP9 Antikörper) was higher in survivors.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Decreased MMP-9 (zeige MMP9 Antikörper) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (zeige EGF Antikörper) on MMP-9 (zeige MMP9 Antikörper) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (zeige TNF Antikörper), and hepatocyte growth factor (zeige HGF Antikörper) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (zeige TIMP2 Antikörper) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (zeige TIMP2 Antikörper) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (zeige TIMP2 Antikörper) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Results provide evidence for the utility of MMP9 (zeige MMP9 Antikörper) and TIMP1 as markers of age- and lactocrine-sensitive porcine female reproductive tract development.

  2. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Antikörper), TIMP1, and NGAL (zeige LCN2 Antikörper) (also MMP2 (zeige MMP2 Antikörper) in 220 kDa complex) without proteolytic activity.

  3. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA Antikörper), pro-MMP-9 (zeige MMP9 Antikörper), MMP-2 (zeige MMP2 Antikörper), VEGFR-1 (zeige FLT1 Antikörper), VEGFR-2 (zeige KDR Antikörper), and TIMP-1, which may contribute to the development of venous stenosis.

  4. Results indicate that leukemia inhibitory factor (LIF (zeige LIF Antikörper)) and Oncostatin M (zeige OSM Antikörper) increase the expression of MMP-1 (zeige MMP1 Antikörper), MMP-3 (zeige MMP3 Antikörper), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (zeige LIF Antikörper) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (zeige MMP2 Antikörper), MMP-9 (zeige MMP9 Antikörper) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaktionspartner

  1. These results show that MMP-9 (zeige MMP9 Antikörper)/TIMP-1 system disturbance and changes of histological structure in uteri tissue are involved in fluoride-induced reproductive dysfunctions.

  2. Tissue inhibitor of matrix metalloproteinases 1 (TIMP1) inhibition resensitized tumors to gemcitabine and radiotherapy.

  3. proteomic analysis of the mesenchymal stem cells secretome identified the TIMP-1 as a potential effector molecule responsible for the anti-angiogenic properties of MSC (zeige MSC Antikörper)

  4. TIMP1 signaling via CD63 (zeige CD63 Antikörper) leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  5. This study highlights a previously undescribed integral role for TIMP1 in both vascular network maturation and adaptations to ischemia or alterations in flow.

  6. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  7. demonstrate that TIMP-2 (zeige TIMP2 Antikörper) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  8. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (zeige CD63 Antikörper).

  9. TIMP-1 is a ligand of LRP-1 (zeige LRP1 Antikörper) and we highlight a new example of its MMP-independent, cytokine-like functions.

  10. RAB37 (zeige RAB37 Antikörper) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (zeige MMP9 Antikörper) migration axis in vitro and in vivo and to suppress tumor metastasis.

TIMP1 Antigen-Profil

Protein Überblick

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Genbezeichner und Symbole assoziert mit TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) Antikörper
  • TIMP metallopeptidase inhibitor 1 (Timp1) Antikörper
  • tissue inhibitor of metalloproteinase 1 (Timp1) Antikörper
  • Clgi Antikörper
  • DKFZp468A0912 Antikörper
  • EPA Antikörper
  • EPO Antikörper
  • HCI Antikörper
  • Timp Antikörper
  • TIMP-1 Antikörper
  • TIMP1 Antikörper

Bezeichner auf Proteinebene für TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPEZIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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