anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Antikörper

The protein encoded by TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. Zusätzlich bieten wir Ihnen TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TIAL1 7073 Q01085
TIAL1 21843 P70318
TIAL1 361655  
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Top anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Antikörper auf antikoerper-online.de

Showing 10 out of 34 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, IHC, WB ABIN571096 (2 µg/mL) staining of K562 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN571096 (3.8 µg/mL) staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg 6 bis 7 Tage
$429.84
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TIAL1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate TIAL1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL 2 bis 3 Tage
$249.00
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg 2 bis 3 Tage
$515.63
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p), WB   0.1 mg 4 bis 8 Tage
$462.00
Details
Fledermaus Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TIAL1 / TIAR antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of extracts of various cell lines, using TIAL1 antibody (ABIN1877102) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), IP Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml. 100 μL 11 bis 14 Tage
$595.83
Details
Hund Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using TIAL1 antibody (ABIN5973602) at 1:3000 dilution. 100 μL 11 bis 16 Tage
$426.40
Details

Am meisten referenzierte anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Antikörper

  1. Human Polyclonal TIAL1 Primary Antibody für WB - ABIN4359656 : Zampedri, Tinoco-Cuellar, Carrillo-Rosas, Diaz-Tellez, Ramos-Balderas, Pelegri, Maldonado: Zebrafish P54 RNA helicases are cytoplasmic granule residents that are required for development and stress resilience. in Biology open 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal TIAL1 Primary Antibody für ELISA, IHC - ABIN4359655 : Yeowell, Walker, Mauger, Seth, Garcia-Blanco: TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. in The Journal of investigative dermatology 2009 (PubMed)

Weitere Antikörper gegen TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Interaktionspartner

Human TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaktionspartner

  1. Depletion of TIAR accelerates mitotic entry and leads to chromosomal instability in response to replication stress, in a manner that can be alleviated by the concomitant depletion of Cdc25B or inhibition of CDK1. Since TIAR retains CDK1 in GMGs and attenuates CDK1 activity, we propose that the assembly of GMGs may represent a so far unrecognized mechanism that contributes to the activation of the G2/M checkpoint

  2. The manipulation of miR2233p/TIAL1 interaction may be involved in the neuroprotective effects of DEX.

  3. Data indicate that both ELAVL1 and TIAR positively regulate endogenous SNCA in vivo.

  4. we identified MT1JP as a critical factor in restraining cell transformation by modulating p53 translation through interactions with TIAR

  5. Data suggest that TPD52 (tumor protein D52) and a TPD52 fragment (residues 78-280) along with TIA-1 (T-cell intracellular antigen-1) and TIAR (TIA-1-related protein) contribute to mRNA stability as cis-acting and trans-acting factors; 3prime-untranslated regions of TPD52, TPD53, and TPD54 regulate expression of their respective genes in a post-transcriptional manner by altering mRNA stability.

  6. results suggest that TIA-1 and TIAR are two new host factors that interact with 5-UTR of EV71 genome and positively regulate viral replication

  7. TIAL1 inhibition of the exon 8 exclusion led to a decrease in SIRT1-Exon8 mRNA levels.

  8. TIA proteins can function as long-term regulators of the ACTB mRNA metabolism in mouse and human cells.

  9. A role for TIAR is identified in T-cells for control of translational specificity.

  10. findings demonstrate that TIAR recognition motif 2 (RRM2), together with its C-terminal extension, is the major contributor for the high-affinity (nM) interactions of TIAR with target RNA sequences

  11. TIA1 and TIAR proteins are intron-associated positive regulators of SMN2 exon 7 splicing.

  12. Severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1alpha expression.

  13. Data show that TIA1 and TIAL1 bind at the same positions on human RNAs, and are consistent with a model where TIA proteins shorten the time available for definition of an alternative exon by enhancing recognition of the preceding 5' splice site.

  14. Data show that apoptotic (TIAR and TIA-1) marker expression in thyroid tissues from adolescents with immune thyroid diseases is higher than in non-immune thyroid diseases.

  15. results report the identification of TIAR as a novel player in the regulation of calcitonin/CGRP alternative RNA processing

  16. activated during HSV-1 infection and accumulated in cytoplasm of cells 6 hr after infection

  17. HuR, KSRP and TIAR are bound to one or more loci in the 3'UTR of IL-8 in breast cancer cells.

  18. TIAR seems to be involved in the post-transcriptional regulation of human iNOS expression

  19. Furthermore, we found that overexpression of DISC1 in SH-SY5Y cells induces the assembly of eIF3- and TIA-1-positive stress granules (SGs), discrete cytoplasmic granules formed in response to environmental stresses.

  20. TIAR-mediated inhibition of translation factor expression elicits a sustained repression of protein biosynthesis in cells responding to stress.

Mouse (Murine) TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaktionspartner

  1. Silencing of TIAR in chronic myeloid leukemia cells strongly elevated BRCA1.

  2. TIA proteins can function as long-term regulators of the ACTB mRNA metabolism in mouse and human cells.

  3. Either TIA1 or TIAR inactivation broadly alter normal development-associated signalling pathways in murine embryonic fibroblasts.

  4. study reports the importance of the tightly balanced expression of the RNA-binding protein TIAR for normal embryonic development, thereby emphasizing the role of post-transcriptional regulations in early embryonic programming

  5. prion-like aggregation of TIA-1 regulates stress granules formation downstream of eIF2alpha phosphorylation in response to stress

  6. in addition to transcriptional regulation, another mechanism by which apigenin prevents COX-2 expression is through mediating TIAR suppression of translatino

  7. TIAR regulates the relative expression of TIA-1 isoforms.

  8. TIA1 and TIAL1 regulate the alternate splicing of lysyl hydroxylase 2

  9. The intronic splicing enhancer of minute virus of mice binds the cellular RNA-processing proteins TIA-1 and TIAR, which enhance usage of the nonconsensus donor.

  10. SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR) and has a role in impaired post-transcriptional regulation of vascular endothelial growth factor

TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.

Genbezeichner und Symbole assoziert mit TIAL1

  • TIA1 cytotoxic granule associated RNA binding protein like 1 (TIAL1) Antikörper
  • Tia1 cytotoxic granule-associated RNA binding protein-like 1 (Tial1) Antikörper
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1 (tial1) Antikörper
  • TIA1 cytotoxic granule associated RNA binding protein like 1 (Tial1) Antikörper
  • 5330433G13Rik Antikörper
  • AL033329 Antikörper
  • mTIAR Antikörper
  • tcbp Antikörper
  • tiar Antikörper
  • zgc:66130 Antikörper

Bezeichner auf Proteinebene für TIAL1

T-cluster binding protein , TIA-1-related nucleolysin , aging-associated gene 7 protein , nucleolysin TIAR , TIA-1-related protein , Tial1 cytotoxic granule-associated RNA binding protein-like 1 , Tial1 cytotoxic granule-associated RNA-binding protein-like 1 , RNA binding protein TIAR (TIA-1 related) , Tial 1 cytotoxic granule-associated RNA- binding protein-like 1

GENE ID SPEZIES
7073 Homo sapiens
21843 Mus musculus
361655 Rattus norvegicus
394107 Danio rerio
100381100 Xenopus laevis
477841 Canis lupus familiaris
614540 Bos taurus
100718733 Cavia porcellus
100158186 Sus scrofa
100058604 Equus caballus
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