anti-THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1) Antikörper

The protein encoded by THAP1 contains a THAP domain, a conserved DNA-binding domain. Zusätzlich bieten wir Ihnen THAP1 Proteine (11) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
THAP1 55145 Q9NVV9
THAP1 73754 Q8CHW1
THAP1 306547 Q5U208
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Top anti-THAP1 Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using THAP1 antibody. Immunohistochemistry of paraffin-embedded rat heart using THAP1 antibody. 200 μL 12 bis 14 Tage
$438.90
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using THAP1 antibody (ABIN5975558) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat heart using THAP1 antibody (ABIN5975558) at dilution of 1/100 (40x lens). 100 μL 11 bis 16 Tage
$426.40
Details
Human Maus Unkonjugiert Fig. 1. Black line: Control Antigen (100 ng) 100 μg 11 bis 16 Tage
$469.05
Details
Human Maus Unkonjugiert IF, RNAi, ELISA, WB Western blot analysis of THAP1 over-expressed 293 cell line, cotransfected with THAP1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with THAP1 monoclonal antibody (M01), clone 2C1-2F2. GAPDH ( 36.1 kDa ) used as specificity and loading control. Western Blot analysis of THAP1 expression in transfected 293T cell line by THAP1 monoclonal antibody (M01), clone 2C1-2F2.Lane 1: THAP1 transfected lysate(24.9 KDa).Lane 2: Non-transfected lysate. 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IP, WB THAP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of THAP1 expression in Jurkat. Immunoprecipitation of THAP1 transfected lysate using anti-THAP1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with THAP1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Western blot analysis using THAP1 mAb against human THAP1 (AA: 1-213) recombinant protein. (Expected MW is 50.3 kDa) 0.1 mg 3 bis 4 Tage
$430.10
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using THAP1 antibody. Immunofluorescence analysis of A549 cell using THAP1 antibody. 100 μL 11 bis 13 Tage
$366.77
Details
Human Maus Unkonjugiert WB Western Blot analysis of THAP1 expression in transfected 293T cell line by THAP1 MaxPab polyclonal antibody.Lane 1: THAP1 transfected lysate(23.43 KDa).Lane 2: Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of THAP1 expression in transfected 293T cell line by THAP1 MaxPab polyclonal antibody.Lane 1: THAP1 transfected lysate(24.90 KDa).Lane 2: Non-transfected lysate. THAP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of THAP1 expression in Jurkat. 100 μg 11 bis 12 Tage
$425.71
Details
Human Kaninchen Alkaline Phosphatase (AP) IF, IHC, WB   100 μL 11 bis 14 Tage
$449.17
Details

Am meisten referenzierte anti-THAP1 Antikörper

  1. Mammalian Monoclonal THAP1 Primary Antibody für ISt, IHC - ABIN1305006 : Ortiz-Virumbrales, Ruiz, Hone, Dolios, Wang, Morant, Kottwitz, Ozelius, Gandy, Ehrlich: Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions. in Acta neuropathologica communications 2015 (PubMed)

Weitere Antikörper gegen THAP1 Interaktionspartner

Human THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1) Interaktionspartner

  1. Dysfunction in similar pathways occurring with mutations in THAP1 as well as diverse dystonia genes highlight a point of convergence in the pathophysiology of several forms of inherited dystonia.

  2. The region of amino acids 139-185 is involved in formation of THAP1 homodimers.

  3. We functionally characterized for the first time three dystonia-causing missense variants (p.N136K, p.N136S and p.Y137C) within the HBM in the C-terminal region of THAP1. Dystonia-causing mutations affecting the residues N136 and Y137 in THAP1 significantly reduced HCFC1 recruitment to all four tested promoter regions.

  4. that the THAP1 is likely to have a causative role in the pathogenesis of Indian primary pure dystonia patients

  5. This study demonstrated that whole-exome sequencing show reveled THAP1 mutation with early-onset generalized dystonia.

  6. Genetic screening targeted at currently known disease-causing mutations in TOR1A, THAP1, and TUBB4 appears to have low diagnostic yield in sporadic spasmodic dysphonia. In our cohort, only 2 patients tested positive for novel/rare variants in THAP1.

  7. A deleterious THAP1 mutation was identified in patients with idiopathic isolated dystonia.

  8. there might not be an association between TOR1A or THAP1 and patients with adult-onset primary focal dystonia

  9. findings strongly suggest the role of other genetic factors or environmental triggers in the pathogenesis of dystonia related to mutations in THAP1 gene.

  10. The aim of this study was to assess the presence of DYT6 mutations in Polish patients with isolated dystonia. It shows known and novel substitutions.

  11. THAP1 variants are an important cause of dystonia among individuals with an early-onset disease and a positive family history.

  12. This study demonistrated that Combined occurrence of a novel TOR1A and a THAP1 mutation in primary dystonia.

  13. this study identified a feedback-loop in the regulation of THAP1 expression and demonstrated that mutant THAP1 leads to higher THAP1 expression levels.

  14. Primary dystonia in the Amish-Mennonites is genetically diverse and includes not only the THAP1 indel founder mutation but also different mutations in THAP1 and GNAL as well as the TOR1A GAG deletion.

  15. This study suggest that the clinical disease course in dystonia patients with mutation of THAP1 in Japanese'

  16. Our results indicate that certain mutations in the THAP1 gene may lead to primary dystonia with remarkable intrafamilial clinical variability.

  17. deletion of SLC20A2 and THAP1 may have a role in familial basal ganglia calcification with dystonia [case report and family study]

  18. Current known dystonia genes include those related to dopamine metabolism, transcription factor, cytoskeleton, transport of glucose and sodium ion, etc.

  19. Par-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells.

  20. The genotypic spectrum of THAP1 and strengthen the association with upper body involvement, including the cranial and cervical regions that are usually spared in DYT1-primary dystonia.

Mouse (Murine) THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1) Interaktionspartner

  1. Dysfunction in similar pathways occurring with mutations in THAP1 as well as diverse dystonia genes highlight a point of convergence in the pathophysiology of several forms of inherited dystonia.

  2. Wild-type THAP1 regulates embryonic stem cell (ESC) potential, survival, and proliferation. Loss of THAP1 or replacement with a disease-causing mutation results in an enhanced rate of cell death, prolongs Nanog, Prdm14, and/or Rex1 expression upon differentiation, and results in failure to upregulate ectodermal genes.

  3. These studies establish a role for THAP1 transcriptional regulation at the inception of myelination and implicate abnormal timing of myelination in the pathogenesis of childhood-onset dystonia.

THAP1 Antigen-Profil

Protein Überblick

The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit THAP1

  • THAP domain containing, apoptosis associated protein 1 (thap1) Antikörper
  • THAP domain containing 1 (THAP1) Antikörper
  • THAP domain containing, apoptosis associated protein 1 L homeolog (thap1.L) Antikörper
  • THAP domain containing, apoptosis associated protein 1 (Thap1) Antikörper
  • THAP domain containing 1 (Thap1) Antikörper
  • THAP domain containing 1 (thap1) Antikörper
  • 4833431A01Rik Antikörper
  • AW490810 Antikörper
  • DYT6 Antikörper
  • THAP1 Antikörper
  • thap1-a Antikörper
  • zgc:136597 Antikörper

Bezeichner auf Proteinebene für THAP1

THAP domain-containing protein 1 , THAP domain containing, apoptosis associated protein 1 , THAP domain-containing protein 1 A , 4833431A01Rik , THAP domain protein 1 , nuclear proapoptotic factor , THAP domain-containing apoptosis-associated protein 1

GENE ID SPEZIES
448407 Xenopus (Silurana) tropicalis
472751 Pan troglodytes
495360 Xenopus laevis
705845 Macaca mulatta
100172198 Pongo abelii
100347939 Oryctolagus cuniculus
55145 Homo sapiens
73754 Mus musculus
306547 Rattus norvegicus
538615 Bos taurus
431620 Gallus gallus
475569 Canis lupus familiaris
692315 Danio rerio
100196187 Salmo salar
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