anti-TAP Binding Protein (Tapasin) (TAPBP) Antikörper

TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. Zusätzlich bieten wir Ihnen TAPBP Kits (10) und TAPBP Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TAPBP 21356 Q9R233
TAPBP 6892 O15533
TAPBP 25217  
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Top anti-TAPBP Antikörper auf antikoerper-online.de

Showing 10 out of 52 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human Skin 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TAPBP Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  OVCAR-3 cell lysate TAPBP is supported by BioGPS gene expression data to be expressed in OVCAR3 WB Suggested Anti-TAPBP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: OVCAR-3 cell lysate  TAPBP is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Hund Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-TAPBP Antibody Titration:  0.2-1 ug/ml  Positive Control:  293T cell lysate WB Suggested Anti-TAPBP <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.93T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western Blot: Tapasin Antibody [NBP1-59938] - Sample Type: Human Fetal Muscle Antibody Dilution: 1.0 ug/ml Western Blot: Tapasin Antibody [NBP1-59938] - Sample Type: Human Adult Placenta Antibody Dilution: 1.0 ug/ml 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of HT-29 cells, using TAPBP antibody (ABIN5971019) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human stomach using TAPBP Antibody (ABIN5971019) at dilution of 1/200 (40x lens). 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated fo ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of A431 cell lysate, using TAPBP Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276986 at 1/100 staining Rat colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert WB TAPBP Antibody (N-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TAPBP antibody detected the TAPBP protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details

Am meisten referenzierte anti-TAPBP Antikörper

  1. Human Polyclonal TAPBP Primary Antibody für IHC, IHC (p) - ABIN4357823 : Sokol, Koelzer, Rau, Karamitopoulou, Zlobec, Lugli: Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. in Journal of translational medicine 2015 (PubMed)

Weitere Antikörper gegen TAPBP Interaktionspartner

Mouse (Murine) TAP Binding Protein (Tapasin) (TAPBP) Interaktionspartner

  1. Absence of Tpn or ERAAP independently altered the peptide repertoire by causing loss as well as gain of new pMHC I. Tpn defined the characteristic carboxy termini of canonical MHC I peptides.

  2. modification of Tapasin can enhance the presentation of targeting antigens via intracellular delivery to DCs and elicit specific CTL immune responses efficiently

  3. Data show that tapasin expression is enhanced by beta 2-microglobulin (zeige B2M Antikörper) via both transcriptional and post-transcriptional mechanisms.

  4. Deletion of a loop within the tapasin C-terminal Ig-like domain (Delta334-342) prevented tapasin association with the MHC class I molecule K(d).

  5. E2F1 (zeige E2F1 Antikörper) is an essential transcription factor for tapasin.

  6. showed that a large disulfide-bonded complex was present in the mouse cells that included ERp57 (zeige PDIA3 Antikörper), tapasin, and K(d).

  7. Role of tapasin in MHC class I antigen presentation in vivo.

  8. Data show that cell surface expression of TAP-independent class I complexes is modulated by tapasin levels and is enhanced by interferon-gamma (zeige IFNG Antikörper).

  9. tapasin has a essential function of tapasin in quality control of HLA-G (zeige HLAG Antikörper) molecules

  10. A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.

Human TAP Binding Protein (Tapasin) (TAPBP) Interaktionspartner

  1. The results demonstrated that the mRNA expression levels of tapasin were significantly downregulated in patients with chronic hepatitis B (CHB) compared with in healthy controls and patients with acute hepatitis B Furthermore, the apoptotic rate of CD8 (zeige CD8A Antikörper)+ T cells was increased in patients with CHB compared with in the other two groups.

  2. The disruption of TAP1 (zeige TAP1 Antikörper) and TAPBP generates pluripotent embryonic stem cells with reduced immunogenicity.

  3. Fluctuation and entropy analyses show how tapasin chaperones major histocompatibility complex class I by stabilising it in a peptide-receptive conformation.

  4. reduction in tapasin expression is associated with tumor progression in colorectal cancer

  5. Data suggest that tapasin (Tsn) binds to MHC I with suboptimal cargo and thereby adjusts the energy landscape in favor of MHC I complexes with immunodominant epitopes.

  6. TAP/TPN complex formation is driven by hydrophobic interactions via leucine zipper-like motifs.

  7. TAP2 (zeige TAP2 Antikörper), HLA-DOA (zeige HLA-DOA Antikörper), HLA-DOB (zeige HLA-DOB Antikörper), and tapasin loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  8. Analysis of expression of tapasin and/or HLA-I may be of value as prognostic tool for glioblastoma multiforme patients, especially when considering immunotherapy.

  9. Modified TAPBP gene function may contribute to the development of refractory chronic rhinosinusitis via reduction of circulating CD8 (zeige CD8A Antikörper) lymphocytes.

  10. Targeted re-sequencing identified rs3106189 at the 5' UTR (zeige UTS2R Antikörper) of TAPBP and rs1052918 at the 3' UTR (zeige UTS2R Antikörper) of TCF3 (zeige TCF3 Antikörper) to be associated with the overall survival of colorectal cancer patients.

TAPBP Antigen-Profil

Protein Überblick

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit TAPBP

  • TAP binding protein (tapasin), tandem duplicate 1 (tapbp.1) Antikörper
  • TAP binding protein (tapbp) Antikörper
  • TAP binding protein (TAPBP) Antikörper
  • TAP binding protein (Tapbp) Antikörper
  • D17Wsu91e Antikörper
  • mhc1uda Antikörper
  • mhc1ufa Antikörper
  • NGS17 Antikörper
  • SI:dZ179B20.1 Antikörper
  • SI:dZ179B20.3 Antikörper
  • SI:dZ179B20.7 Antikörper
  • TAPA Antikörper
  • TAPBP Antikörper
  • TPN Antikörper
  • TPSN Antikörper
  • zgc:109814 Antikörper

Bezeichner auf Proteinebene für TAPBP

tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN

GENE ID SPEZIES
30163 Danio rerio
100136493 Salmo salar
100170652 Ovis aries
21356 Mus musculus
6892 Homo sapiens
504335 Bos taurus
25217 Rattus norvegicus
417048 Gallus gallus
481740 Canis lupus familiaris
Ausgewählte Anbieter für anti-TAPBP (TAPBP) Antikörper
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