anti-Synaptonemal Complex Protein 3 (SYCP3) Antikörper

SYCP3 encodes an essential structural component of the synaptonemal complex. Zusätzlich bieten wir Ihnen SYCP3 Proteine (8) und SYCP3 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SYCP3 20962 P70281
SYCP3 50511 Q8IZU3
SYCP3 25561 Q63520
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Top anti-SYCP3 Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Cat Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, WB SCP3 labeled in mouse pachytene preparation (red), using ABIN152572. CDK2 staining, near teleomeres, is also present (green). Immunohistochemistry-Paraffin: SCP3 Antibody [ABIN152572] - Analysis of SCP3 in human testis using DAB with hematoxylin counterstain. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$516.98
Details
Human Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, WB SCP3 labeled in mouse pachytene preparation (red), using ABIN152571. CDK2 staining, near teleomeres, is also present (green). Punctate staining of murine SCP3 in mouse ovary using ABIN152571. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$516.98
Details
Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC SCP3 labeled in mouse pachytene preparation (red), using ABIN152570. CDK2 staining, near teleomeres, is also present (green). Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody  - IHC analysis of formalin fixed paraffin-embedded (FFPE) human testis using SCP3 antibody at 1:500 on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0) and endogenous peroxidase quenching with peroxide block. The sections were incubated with primary antibody for 30 minutes and Bond Polymer Refine Detection (Leica Biosystems) with DAB was used for signal development followed by counterstaining with hematoxylin. Whole slide scanning and capturing of representative images was performed using Aperio AT2 (Leica Biosystems). Nuclear staining was observed. Staining was performed by Histowiz. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$418.10
Details
Human Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-SYCP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-SYCP3 antibody (ARP58334_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using SYCP3 mAb against human SYCP3 recombinant protein. (Expected MW is 37.2 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$577.50
Details
Human Kaninchen Unkonjugiert WB Anti-SCP3 Picoband antibody,  All lanes: Anti SCP3  at 0.5ug/ml WB: Recombinant Human SCP3 Protein 0.5ng Predicted bind size: 41KD Observed bind size: 41KD Anti-SCP3 Picoband antibody,  All lanes: Anti SCP3  at 0.5ug/ml WB:  Whole Cell Lysate at 40ug Predicted bind size: 28KD Observed bind size: 28KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: SCP3/SYCP3 Antibody (6F9C5) [NBP2-23487] - Analysis of Jurkat cells using SCP3 mouse mAb (green) and negative control (red). Immunohistochemistry: SCP3/SYCP3 Antibody (6F9C5) [NBP2-23487] - Analysis of paraffin-embedded kidney tissues using SYCP3 mouse mAb with DAB staining. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$418.10
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Anti-SYCP3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958326 concentration 5 ug/ml. Anti-SYCP3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other for ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody  - Breast cancer Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody  - Staining of human testis shows moderate nuclear positivity in cells in seminiferus ducts. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details

Am meisten referenzierte anti-SYCP3 Antikörper

  1. Cat (Feline) Polyclonal SYCP3 Primary Antibody für ICC, IHC (fro) - ABIN152572 : Liu, Wu, Lyu, Yang, Albertini, Keefe, Liu: Germline stem cells and neo-oogenesis in the adult human ovary. in Developmental biology 2007 (PubMed)
    Show all 37 Pubmed References

  2. Human Polyclonal SYCP3 Primary Antibody für ICC, IHC (fro) - ABIN152571 : Dann, Alvarado, Molyneux, Denard, Garbers, Porteus: Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiation. in Stem cells (Dayton, Ohio) 2008 (PubMed)
    Show all 23 Pubmed References

  3. Cow (Bovine) Polyclonal SYCP3 Primary Antibody für ICC, IF - ABIN152570 : Takada, Isono, Shinga, Turner, Kitamura, Ohara, Watanabe, Singh, Kamijo, Jenuwein, Burgoyne, Koseki: Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. in Development (Cambridge, England) 2007 (PubMed)
    Show all 18 Pubmed References

  4. Human Monoclonal SYCP3 Primary Antibody für ICC, FACS - ABIN1724891 : Alsheimer, Baier, Schramm, Schütz, Benavente: Synaptonemal complex protein SYCP3 exists in two isoforms showing different conservation in mammalian evolution. in Cytogenetic and genome research 2010 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal SYCP3 Primary Antibody für ICC, FACS - ABIN1724892 : Chung, Kitano, Takikita, Cho, Noh, Kim, Ylaya, Hanaoka, Fukuoka, Hewitt: Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer. in Human pathology 2013 (PubMed)
    Show all 2 Pubmed References

  6. Polyclonal SYCP3 Primary Antibody für IF, IHC (p) - ABIN540276 : Onorato, Brown, Morris: Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2. in Journal of andrology 2008 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal SYCP3 Primary Antibody für ELISA, FACS - ABIN4352291 : Zhuang, Tang, Feng, Liu, Zhu, Yan, Liu, Liu, Qiao: Trim27 interacts with Slx2, is associated with meiotic processes during spermatogenesis. in Cell cycle (Georgetown, Tex.) 2016 (PubMed)

Weitere Antikörper gegen SYCP3 Interaktionspartner

Mouse (Murine) Synaptonemal Complex Protein 3 (SYCP3) Interaktionspartner

  1. SYCP1 and SYCP3 act at the centromeres to promote the establishment and/or maintenance of centromere pairing and, by doing so, improve the segregation fidelity of mammalian meiotic chromosomes.

  2. Unlike other vertebrates, rat and mouse SYCP3 exists in 2 isoforms; the short isoform is conserved in vertebrates and the longer isoform, appeared 15 million years ago in a common ancestor of rat and mouse and after separation from the hamster branch.

  3. X-linked lymphocyte-regulated protein pM1 (XMR), XLR, and SCP3 render tumor cells resistant to antitumor immunity

  4. absence of synaptonemal complex protein 3 (SCP3) promotes aneuploidy in murine oocytes by inducing defective meiotic chromosome segregation

  5. In Scp3-deficient (knockout) mice, spermatogenesis and testicular degeneration are augmented when E2F1 is also deficient.

  6. Rad21, and the superimposed SCP3 and SCP2, are involved in the monopolar attachment of sister kinetochores during meiosis I

  7. SYCP2 and SYCP3 proteins function in the specificity of chromatin attachment to the chromosome core

  8. SYCP3 has a temporally restricted role in maintaining, but not establishing, cohesin-core organization during prophase I.

  9. The SYCP3 is expressed in germ cell-like cells. The nuclear distribution of SYCP3 in the germ cell-like cells is highly abnormal and not associated with the chromosomes of these cells.

  10. DNA double-stranded breaks are inefficiently repaired in Sycp3(-)(/)(-) oocytes, thereby generating a temporal spectrum of recombination errors. T

  11. Sycp3 is a biologically relevant target of Dazl-mediated translation in mammals.

Human Synaptonemal Complex Protein 3 (SYCP3) Interaktionspartner

  1. SCP3 is associated with lymphangiogenesis and provides insight into the SCP3-VEGF-C/VEGF-D axis based cancer therapy strategy.

  2. In the model, the reported compaction of chromosomal DNA caused by SYCP3 would result from its ability to bridge distant sites on a DNA molecule with the DNA-binding domains located at each end of its strut-like structure.

  3. SYCP3 binds to RAD51 and attenuates RAD51 activity during meiosis.

  4. SYCP3 binding and assembly on meiotic chromosomes leads to their organisation into compact structures compatible with recombination and crossover formation

  5. The T657C polymorphism of the SYCP3 gene is possibly associated with recurrent pregnancy loss of unknown cause in human.

  6. SCP3 plays an important role in the progression of cervical cancer

  7. SYCP3 mutations are not associated with the genetic susceptibility for meiotic arrest in infertile male patients with nonobstructive azoospermia in the Turkish population

  8. screening for genetic variants in AURKB and SYCP3 among these patients with reproductive problems using Sanger sequencing. Only one apparently non-pathogenic deletion was found in SYCP3.

  9. Positive synaptonemal complex protein 3 expression is a portent of poor outcome and may be a potential biomarker in the early stages of the non-small cell lung cancer for survival.

  10. mutations in SYCP3 do not contribute significantly to risk for recurrent miscarriage through maternal meiotic nondisjunction.

  11. Expression of SYCP3 inhibits the homologous recombination (HR) pathway mediated by RAD51.

  12. The 657T>C mutation of SYCP3 may not be associated with recurrent miscarriage caused by aneuploidy.

  13. mutation analysis of SYCP3, DNMT3L and MSH4 in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages; heterozygous change, detected in a conserved functional domain of the SYCP3 gene, was absent in >200 controls

  14. X-linked lymphocyte-regulated protein pM1 (XMR), XLR, and SCP3 render tumor cells resistant to antitumor immunity

  15. We suggest that SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein via dominant negative interference.

  16. In contrast to previously reported high frequency of SYCP3 mutations in patients with azoospermia, only polymorphisms are found in the present study

  17. SYCP3 is expressed in human testis and is restricted to germ cells. Lack of SYCP3 expression in human testis may have a negative effect on spermatogenesis and male fertility.

  18. No functional SYCP3 exonic SNP was found in infertile Spanish patients with meiosis arrest, suggesting that SYCP3 mutations very likely are not relevant in Spain in genetic susceptibility to meiosis arrest.

  19. These observations suggest that SCP3 is expressed in adult human and monkey ovaries.

  20. mutations in SYPR3 are likely to generate an aberrant synaptonemal complex in a dominant-negative manner and contribute to abnormal chromosomal behavior that might lead to recurrent miscarriage.

SYCP3 Antigen-Profil

Protein Überblick

This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit SYCP3

  • synaptonemal complex protein 3 (Sycp3) Antikörper
  • synaptonemal complex protein 3 (SYCP3) Antikörper
  • synaptonemal complex protein 3 (sycp3) Antikörper
  • synaptonemal complex protein 3 (scp3) Antikörper
  • synaptonemal complex protein 3 L homeolog (sycp3.L) Antikörper
  • COR1 Antikörper
  • MGC146429 Antikörper
  • RNASCP3 Antikörper
  • SCP-3 Antikörper
  • scp3 Antikörper
  • SPGF4 Antikörper
  • sycp3 Antikörper

Bezeichner auf Proteinebene für SYCP3

SCP-3 , synaptonemal complex protein 3-like , synaptonemal complex protein 3 , Meiotic chromosome core protein , Synaptonemal complex protein COR1

GENE ID SPEZIES
20962 Mus musculus
50511 Homo sapiens
25561 Rattus norvegicus
418097 Gallus gallus
452174 Pan troglodytes
615896 Bos taurus
779673 Xenopus (Silurana) tropicalis
100049288 Oryzias latipes
100136243 Oncorhynchus mykiss
100137700 Xenopus laevis
101825388 Mesocricetus auratus
Ausgewählte Anbieter für anti-SYCP3 (SYCP3) Antikörper
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