SYCP3 Antikörper (AA 18-223)

Produktnummer ABIN3043305

Der Kaninchen Polyklonal anti-SYCP3 Antikörper (ABIN3043305) detektiert spezifisch SYCP3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SYCP3 Antikörper (AA 18-223) (ABIN3043305)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYCP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYCP3 Antikörper

Bindungsspezifität: AA 18-223

Verwendungszweck: Anti-SCP3/SYCP3 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human SCP3 shares 72%,73% amino acid (aa) sequences identity with mouse,rat SCP3,respectively.

Produktmerkmale: Anti-SCP3/SYCP3 Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Andere Bezeichnung: SYCP3

Hintergrund:

Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

Gene Full Name: synaptonemal complex protein 3

Molekulargewicht: 28 kDa

Gen-ID: 50511

UniProt: Q8IZU3