Surfactant Protein D Proteine (SFTPD)

Contributes to the lung's defense against inhaled microorganisms. Zusätzlich bieten wir Ihnen Surfactant Protein D Antikörper (174) und Surfactant Protein D Kits (53) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SFTPD 6441 P35247
Ratte SFTPD SFTPD 25350 P35248
SFTPD 20390 P50404
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
Human Cells Rhesusaffen His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 12 bis 15 Tage
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage

SFTPD Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
Mouse (Murine) , ,

Weitere Proteine zu Surfactant Protein D (SFTPD) Interaktionspartnern

Human Surfactant Protein D (SFTPD) Interaktionspartner

  1. Studied predictive value of surfactant protein D (SP-D) in lung cancer patients with interstitial lung disease induced by anticancer agents (ILD-AA). Results suggest that SP-D level change was a risk factor for mortality in patients with ILD-AA, and that SP-D might be a predictive prognostic biomarker of ILD-AA.

  2. SP-D also delays FasL (zeige FASL Proteine)-induced death of primary human T cells. SP-D delaying the progression of the extrinsic pathway of apoptosis could have important implications in regulating immune cell homeostasis at mucosal surfaces

  3. findings suggest that these pulmonary markers could be useful to assess CAP severity and, especially YKL-40 (zeige CHI3L1 Proteine) and CCL18 (zeige CCL18 Proteine) by helping predict CAP caused by atypical pathogens

  4. Trimeric SP-D wildtype recognized larger LPS (zeige IRF6 Proteine) inner core oligosaccharides with slightly enhanced affinity than smaller compounds suggesting the involvement of stabilizing secondary interactions.

  5. rs2819096 in the surfactant protein D (SFTPD) gene was associated with a higher risk of COPD (zeige ARCN1 Proteine) GOLD III + IV.

  6. SP-D increases the formation of nuclear and membrane blebs. Inhibition of caspase-8 (zeige CASP8 Proteine) confirms the effect of SP-D is unique to the caspase-8 (zeige CASP8 Proteine) pathway.

  7. Findings indicate serum pulmonary surfactant protein D (SP-D, SFTPD) level as a potential marker to estimate the efficacy of epidermal growth factor receptor (EGFR (zeige EGFR Proteine))-tyrosine kinase (zeige TXK Proteine) inhibitor (TKIs).

  8. Patients with SP-D 11Thr/Thr (zeige TRH Proteine) genotype were more susceptible to acute kidney injury (AKI). Compared with healthy controls, serum SP-D levels at day 1, 3 and 7 were significantly elevated in AKI patients.

  9. This review intends to provide a current overview of the genetics, structure and extra-pulmonary functions of the surfactant collectin (zeige MBL2 Proteine) proteins.

  10. Meta-analysis found that serum SP-A/D detection might be useful for differential diagnosis and prediction of survival in patients with idiopathic pulmonary fibrosis.

Cow (Bovine) Surfactant Protein D (SFTPD) Interaktionspartner

  1. Elevation of SP-D is found in bronchoalveolar lavage fluid from inoculated lobes of calves infected with bovine adenovirus type 3.

  2. The bSP (zeige KLK6 Proteine)-D gene has 9 exons spanning about 10.5 kb on chromosome 28 at position q1.8. The 5'-upstream sequence has cis (zeige CISH Proteine)-regulatory elements. It has 2 (zeige HAS2 Proteine) polymorphisms in the carbohydrate recognition domain (242 Glu (zeige DCTN1 Proteine)/Val & 268 Ala/Gly).

Pig (Porcine) Surfactant Protein D (SFTPD) Interaktionspartner

  1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.

  2. Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety.

  3. The presence of SP-D in endothelial cells which is NO-, PI(3 (zeige PI3 Proteine))K/Akt (zeige AKT1 Proteine)- and Erk (zeige MAPK1 Proteine)-dependent is demonstrated. It suggests a protective role of SP-D in these cells.

  4. The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen.

Mouse (Murine) Surfactant Protein D (SFTPD) Interaktionspartner

  1. The data provide evidence SP-A (zeige SFTPA1 Proteine) and SP-D attenuate S. aureus pneumonia severity resulting in decreased intestinal mucosal injury, apoptosis, and inflammation.

  2. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A (zeige SFTPA1 Proteine) and SPC (zeige SFTPC Proteine) but not SPB and SPD expression.

  3. Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A (zeige SFTPA1 Proteine), SP-D and MBL-A) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS (zeige TLR4 Proteine) challenge are clues relevant to suggest their involvement in testicular immune privilege.

  4. Our data may promote further studies on the morphological development of the aging lung and the role of SP-D in this process.

  5. The experimentally induced alterations were more severe in the SP-D(-/-) than in the WT mice, particularly with respect to the surfactant-storing lamellar bodies which were sometimes extremely enlarged in SP-D(-/-) mice.

  6. these results demonstrate SP-D plays protective roles by inhibiting apoptosis and modulating NF-kappaB-mediated inflammation in CLP-induced acute pancreatic injury .

  7. SP-A (zeige SFTPA1 Proteine)/D double knock-out mice showed increased susceptibility to urinary tract infection

  8. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  9. The presence of SP-A (zeige SFTPA1 Proteine) and SP-D in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  10. our results demonstrate that SFTPD deficiency affects female fertility, highlighting roles for SFTPD in ovarian and uterine physiology

Horse (Equine) Surfactant Protein D (SFTPD) Interaktionspartner

  1. Surfactant protein D and haptoglobin (zeige HP Proteine) serum concentrations could be a diagnostic aid for equine inflammatory airway disease.

  2. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.

Surfactant Protein D (SFTPD) Protein Überblick

Protein Überblick

Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Genbezeichner und Symbole assoziert mit Surfactant Protein D Proteine (SFTPD)

  • surfactant protein D (SFTPD)
  • surfactant protein D (Sftpd)
  • surfactant protein D (SP-D)
  • surfactant associated protein D (Sftpd)
  • AI573415 Protein
  • COLEC7 Protein
  • PSP-D Protein
  • Sftp4 Protein
  • SP-D Protein
  • SPD Protein

Bezeichner auf Proteinebene für Surfactant Protein D Proteine (SFTPD)

collectin 7 , collectin-7 , lung surfactant protein D , pulmonary surfactant apoprotein , pulmonary surfactant-associated protein D , surfactant, pulmonary-associated protein D , surfactant-associated protein, pulmonary 4 , CP4 , PSP-D , pulmonary surfactant protein D , surfactant associated protein D , surfactant protein D , carbohydrate recognition domain , SP-D , LOW QUALITY PROTEIN: pulmonary surfactant-associated protein D

6441 Homo sapiens
25350 Rattus norvegicus
282072 Bos taurus
397198 Sus scrofa
443191 Ovis aries
489066 Canis lupus familiaris
678657 Macaca mulatta
20390 Mus musculus
100728956 Cavia porcellus
102119038 Macaca fascicularis
100357777 Oryctolagus cuniculus
100066341 Equus caballus
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