Suppressor of Variegation 3-9 Homolog 2 (Drosophila) Proteine (SUV39H2)

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. Zusätzlich bieten wir Ihnen SUV39H2 Antikörper (121) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SUV39H2 79723 Q9H5I1
SUV39H2 64707 Q9EQQ0
Ratte SUV39H2 SUV39H2 364785  
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Showing 8 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,125.83
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,129.50
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,138.67
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Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,138.67
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Escherichia coli (E. coli) Human Unkonjugiert 50 μg Anmelden zum Anzeigen 1 bis 2 Tage
$472.50
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SUV39H2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartnern

Human Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. Our finding unveils a novel autoregulatory mechanism of SUV39H2 through lysine automethylation

  2. Our data show that the differential expression of SUV39H1 (zeige SUV39H1 Proteine) and SUV39H2 is associated with genomic instability and that the modulation of these HMTases can be an attractive approach to prevent CLL evolution

  3. SUV39H2 functioned cooperatively with MAGE-A11 to increase androgen-dependent AR transcriptional activity.

  4. histone H3 (zeige HIST3H3 Proteine) lysine 9 methylation reduction, which may be due to the downregulation of methyltransferase SUV39H2 and the upregulation of demethylase (zeige MBD2 Proteine) KDM4C (zeige KDM4C Proteine), was found in CD4 (zeige CD4 Proteine)(+) T lymphocytes of Latent autoimmune diabetes in adults patients

  5. data cannot finally exclude H2AX (zeige H2AFX Proteine) methylation of SUV39H2 in cells, additional experimental evidence is required to validate this claim.

  6. Our results reveal the regulatory mechanism of LSD1 (zeige KDM1A Proteine) protein through its lysine methylation by SUV39H2 in human cancer cells

  7. We also demonstrate that the N324K mutant in the SET domain of SUV39H2 that has been shown to cause an inherited nasal skin disease in Labrador Retrievers renders SUV39H2 inactive

  8. Expression of JHDM2A (zeige KDM3A Proteine) was significantly increased but HDAC2 (zeige HDAC2 Proteine), HDAC7 (zeige HDAC7 Proteine), and SUV39H2 were significantly down-regulated in Systemic Sclerosis B cells relative to controls

  9. genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective.

  10. findings suggest that Suv39H1 (zeige SUV39H1 Proteine) and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. The authors show here that the mouse Suv39h2 enzyme differs from Suv39h1 (zeige SUV39H1 Proteine) by containing an N-terminal basic domain that facilitates retention at mitotic chromatin and provides an additional affinity for major satellite repeat RNA.

  2. Data indicate that histone methyltransferase Suv39h2 expression is up-regulated in the liver in liver steatosis.

  3. Repeat-associated, Suv39h (zeige SUV39H1 Proteine)-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  4. ESET (zeige SETDB1 Proteine) histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1 (zeige HDAC1 Proteine)/2 that participates in multiple pathways of transcriptional repression.

  5. Taken together, the results indicate epigenetic regulation of telomere length in mammals by Suv39h1 (zeige SUV39H1 Proteine) and Suv39h2.

Pig (Porcine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. Knockdown of SUV39H1 (zeige SUV39H1 Proteine) and SUV39H2 in embryonic stem-like cells and embryonic fibroblasts increases telomere length.

SUV39H2 Protein Überblick

Protein Überblick

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).

Genbezeichner und Symbole assoziert mit SUV39H2

  • suppressor of variegation 3-9 homolog 2 (SUV39H2)
  • suppressor of variegation 3-9 homolog 2 (Drosophila) (Suv39h2)
  • suppressor of variegation 3-9 homolog 2 (Suv39h2)
  • suppressor of variegation 3-9 homolog 2 (suv39h2)
  • suppressor of variegation 3-9 homolog 2 L homeolog (suv39h2.L)
  • 4930507K23Rik Protein
  • AA536750 Protein
  • D030054H19Rik Protein
  • D2Ertd544e Protein
  • kmt1b Protein
  • SUV39H2 Protein

Bezeichner auf Proteinebene für SUV39H2

H3-K9-HMTase 2 , histone H3-K9 methyltransferase 2 , histone-lysine N-methyltransferase SUV39H2 , lysine N-methyltransferase 1B , su(var)3-9 homolog 2 , Suv39h histone methyltransferase , suppressor of variegation 3-9 homolog 2 (Drosophila) , histone-lysine N-methyltransferase SUV39H2-like

GENE ID SPEZIES
79723 Homo sapiens
64707 Mus musculus
364785 Rattus norvegicus
426314 Gallus gallus
466014 Pan troglodytes
477995 Canis lupus familiaris
536936 Bos taurus
549262 Xenopus (Silurana) tropicalis
664651 Sus scrofa
697378 Macaca mulatta
100037174 Xenopus laevis
100401513 Callithrix jacchus
100436926 Pongo abelii
100469547 Ailuropoda melanoleuca
100591032 Nomascus leucogenys
100728513 Cavia porcellus
Ausgewählte Anbieter für SUV39H2 Proteine (SUV39H2)
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