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Functions as a bridging factor between STAT6 and the basal transcription factor. Zusätzlich bieten wir Ihnen SND1 Antikörper (65) und SND1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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The data suggested that JNK (zeige MAPK8 ELISA Kits)-enhanced Tudor-SN phosphorylation promotes the interaction between Tudor-SN and G3BP (zeige G3BP1 ELISA Kits) and facilitates the efficient recruitment of Tudor-SN into stress granules under conditions of sodium arsenite-induced oxidative stress.
SND1 physically associated with and recruited the histone acetylase GCN5 to the promoter regions of Smad2 (zeige SMAD2 ELISA Kits)/3/4, and consequently enhanced the gene transcriptional activation of Smad2 (zeige SMAD2 ELISA Kits)/3/4, which are essential downstream regulators in the TGFbeta1 (zeige TGFB1 ELISA Kits) pathway.
Our work establishes an oncogenic role for SND1 in promoting tumor-initiating cell formation in hepatocellular carcinoma
Findings indicate the potential values of microRNA miR (zeige MLXIP ELISA Kits)-320a, staphylococcal nuclease domain-containing 1 (SND1) and beta-catenin (zeige CTNNB1 ELISA Kits) as prognostic biomarkers and therapeutic candidates for malignant gliomas.
These results highlight SND1 as a potential regulator of cellular cholesterol distribution and homeostasis in hepatoma cells, and support the rationale for the therapeutic use of molecules that influence cholesterol management when SND1 is overexpressed.
This study unravels a novel mechanism of SND1 function and identifies MGLL (zeige MGLL ELISA Kits) as a unique tumor suppressor for HCC. MGLL (zeige MGLL ELISA Kits) might function as a homeostatic regulator of Akt (zeige AKT1 ELISA Kits) restraining its activation.
SND1 is a determinant downstream effector of TNFalpha (zeige TNF ELISA Kits) that contributes to support glycerophospholipid homeostasis in human hepatocellular carcinoma during inflammation.
it could be concluded that miR (zeige MLXIP ELISA Kits)-361-5p functions as a tumor-suppressive miRNA through directly binding to SND1
we identified a new SND1-BRAF fusion that appeared to be present in a subpopulation of tumor cells.
Study is the first to show a novel regulatory role of SND1, a direct target of miR (zeige MLXIP ELISA Kits)-184, in glioma progression, suggesting that the miR (zeige MLXIP ELISA Kits)-184/SND1 axis may be a useful diagnostic and therapeutic tool for malignant glioma.
Tudor-SN is a potential substrate of G1/S phase Cyclin (zeige PCNA ELISA Kits)-Dependent Kinases, and promotes cell cycle progression by facilitating E2F-1 (zeige E2F1 ELISA Kits)-mediated gene transcription.
MTDH (zeige MTDH ELISA Kits) supports the survival of mammary epithelial cells under oncogenic/stress conditions by interacting with and stabilizing SND1.
Tudor-SN and PPARgamma (zeige PPARG ELISA Kits) are both regulated by C/EBPbeta (zeige CEBPB ELISA Kits) during adipogenesis and significantly influence the regulation of PPARgamma (zeige PPARG ELISA Kits) target genes.
p100 regulates the binding activity of RelB (zeige RELB ELISA Kits)/p50 (zeige LSP1 ELISA Kits) dimers via at least two distinct mechanisms depending on the signaling pathway involved.
Two alternative transcripts of p100 are expressed during embryogenesis and regulated by Nodal signaling.
Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Plays a role in cell viability. Functions as a transcriptional coactivator for STAT5. Plays a role in cell viability (By similarity).
EBNA-2 co-activator (100kD)
, 100 kDa coactivator
, EBNA2 coactivator p100
, SND1-BRAF fusion
, p100 EBNA2 co-activator
, p100 co-activator
, staphylococcal nuclease domain containing 1
, staphylococcal nuclease domain-containing protein 1
, tudor domain-containing protein 11
, p105 coactivator
, staphylococcal nuclease and tudor domain containing 1
, 4SNc-Tudor domain protein