Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 Proteine (SOHLH2)

Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).. Zusätzlich bieten wir Ihnen SOHLH2 Antikörper (55) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SOHLH2 54937 Q9NX45
SOHLH2 74434 Q9D489
SOHLH2 619575 Q3MHT3
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,300.00
Details

SOHLH2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) Interaktionspartnern

Human Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) Interaktionspartner

  1. sohlh2 functions as a tumor metastasis suppressor via suppressing IL-8 (zeige IL8 Proteine) expression in breast cancer

  2. Results identified MMP9 (zeige MMP9 Proteine) as a novel target for transcriptional inactivation by Sohlh2 and demonstrated that the Sohlh2 downregulation of MMP9 (zeige MMP9 Proteine) is critical for inhibiting human ovarian cancer cell invasion.

  3. The polymorphisms rs1328626 and rs6563386 of the SOHLH2 gene would be the genetic risk factors for nonobstructive azoospermia in the Chinese population. The SNP rs1328641 might influence testes development in the NOA (zeige DLAT Proteine) patients.

  4. Low Sohlh2 expression is associated with ovarian cancer.

  5. Our identification of novel variants in the SOHLH2 gene, in women with POF (zeige POF1B Proteine) of both Chinese and Serbian origin, strongly suggests an important role for SOHLH2 in human POF (zeige POF1B Proteine) etiology.

Mouse (Murine) Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 2 (SOHLH2) Interaktionspartner

  1. Sohlh1 (zeige SOHLH1 Proteine) and Sohlh2 are essential regulators of oocyte differentiation but do not affect meiosis I.

  2. SOHLH2 is critical for the formation of synaptonemal complexes.

  3. Sohlh2 may inhibit oocyte apoptosis via c-kit/PI3K/Akt (zeige AKT1 Proteine)/Foxo3a (zeige FOXO3 Proteine) signalling pathway

  4. SOHLH1 and SOHLH2 were able to directly and cooperatively repress STRA8 expression in cell lines in vitro through binding to its promoter.

  5. Our findings suggest that an SOHLH2/SOHLH1 (zeige SOHLH1 Proteine)/SP1 (zeige SP1 Proteine) ternary complex autonomously and cooperatively regulates Sohlh1 (zeige SOHLH1 Proteine) gene transcription through juxtaposed E- and GC-boxes during early spermatogenesis and oogenesis.

  6. Effects of BMP4 on mouse primordial follicle growth were assayed by follicle count and TUNEL labeling. The expression of phospho-SMAD1/5/8, Sohlh2, and c-kit were measured by immunohistochemistry, RT-PCR, and Western blotting.

  7. SOHLH1 (zeige SOHLH1 Proteine) and SOHLH2 directly stimulate Kit transcription in postnatal spermatogonia, thus activating the signaling involved in spermatogonia differentiation and spermatogenetic progression.

  8. Data suggest that a dynamic DNA CpG methylation in Sohlh2 and Figlalpha promoters, but not in the intron and exon sequences, is linked to regulation of gene expression, even though CpG islands are also present in their introns or exons.

  9. SOHLH1 (zeige SOHLH1 Proteine) and SOHLH2 suppress genes involved in spermatogonial stem cell maintenance, and induce genes important for spermatogonial differentiation.

  10. The expression pattern of SOHLH2 suggests that it may be a critical regulator of early germ cell development.

SOHLH2 Protein Überblick

Protein Überblick

Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).

Genbezeichner und Symbole assoziert mit SOHLH2

  • spermatogenesis and oogenesis specific basic helix-loop-helix 2 (SOHLH2)
  • spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 (LOC100443062)
  • spermatogenesis and oogenesis specific basic helix-loop-helix 2 (Sohlh2)
  • 4933406N12Rik Protein
  • AI413378 Protein
  • bHLHe81 Protein
  • RGD1304752 Protein
  • SPATA28 Protein
  • TEB1 Protein

Bezeichner auf Proteinebene für SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2-like , spermatogenesis associated 28 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2

GENE ID SPEZIES
452536 Pan troglodytes
486009 Canis lupus familiaris
518810 Bos taurus
693608 Macaca mulatta
100443062 Pongo abelii
100580067 Nomascus leucogenys
54937 Homo sapiens
74434 Mus musculus
619575 Rattus norvegicus
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