Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 Proteine (SOHLH1)

Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development (By similarity)..

alle Proteine anzeigen Gen GeneID UniProt
Human SOHLH1 SOHLH1 402381 Q5JUK2
Maus SOHLH1 SOHLH1 227631 Q6IUP1
Ratte SOHLH1 SOHLH1 362085  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Weitere Proteine zu Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) Interaktionspartnern

Human Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) Interaktionspartner

  1. No association between SOHLH1 SNPs and azoospermia risk in the Chinese population.

  2. In Chinese and Serbian patients with primary ovarian insufficiency, SOHLH1 was found to be a candidate gene.

  3. Findings indicate that a splice-acceptor site mutation that probably causes a nonfunctional SOHLH1 protein results in nonobstructive azoospermia by the lack of normal spermatogenesis.

  4. Sohlh1 and Lhx8 (zeige LHX8 Proteine) are two germ cell-specific, critical regulators of oogenesis

Mouse (Murine) Spermatogenesis and Oogenesis Specific Basic Helix-Loop-Helix 1 (SOHLH1) Interaktionspartner

  1. Sohlh1 and Sohlh2 (zeige SOHLH2 Proteine) are essential regulators of oocyte differentiation but do not affect meiosis I.

  2. SOHLH1 and SOHLH2 were able to directly and cooperatively repress STRA8 expression in cell lines in vitro through binding to its promoter.

  3. Our findings suggest that an SOHLH2 (zeige SOHLH2 Proteine)/SOHLH1/SP1 (zeige SP1 Proteine) ternary complex autonomously and cooperatively regulates Sohlh1 gene transcription through juxtaposed E- and GC-boxes during early spermatogenesis and oogenesis.

  4. SOHLH1 and SOHLH2 (zeige SOHLH2 Proteine) directly stimulate Kit transcription in postnatal spermatogonia, thus activating the signaling involved in spermatogonia differentiation and spermatogenetic progression.

  5. SOHLH1 and SOHLH2 (zeige SOHLH2 Proteine) suppress genes involved in spermatogonial stem cell maintenance, and induce genes important for spermatogonial differentiation.

  6. Sohlh1 represents the first testis-specific (zeige AIF1 Proteine) bHLH transcription factor (zeige MSGN1 Proteine) that is essential for spermatogonial differentiation.

  7. Sohlh1 and Lhx8 (zeige LHX8 Proteine) are two germ cell-specific, critical regulators of oogenesis

SOHLH1 Protein Überblick

Protein Überblick

Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development (By similarity).

Genbezeichner und Symbole assoziert mit SOHLH1

  • spermatogenesis and oogenesis specific basic helix-loop-helix 1 (SOHLH1)
  • spermatogenesis and oogenesis specific basic helix-loop-helix 1 (Sohlh1)
  • bA100C15.3 Protein
  • bHLHe80 Protein
  • C9orf157 Protein
  • Gm110 Protein
  • Nohlh Protein
  • RGD1564440 Protein
  • SPATA27 Protein
  • TEB2 Protein

Bezeichner auf Proteinebene für SOHLH1

newborn ovary helix loop helix , spermatogenesis associated 27 , spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 , helix-loop-helix protein NOHLH

GENE ID SPEZIES
402381 Homo sapiens
227631 Mus musculus
526069 Bos taurus
362085 Rattus norvegicus
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