anti-Sperm Associated Antigen 6 (SPAG6) Antikörper

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Zusätzlich bieten wir Ihnen Sperm Associated Antigen 6 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SPAG6 9576 O75602
SPAG6 50525 Q9JLI7
SPAG6 360747  
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Top anti-Sperm Associated Antigen 6 Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SPAG6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-SPAG6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-SPAG6 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Positive Control: HepG2 cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert WB Western Blot analysis of SPAG6 expression in transfected 293T cell line by SPAG6 MaxPab polyclonal antibody.Lane 1: SPAG6 transfected lysate(55.99 KDa).Lane 2: Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB SPAG6 antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
$449.29
Details
Human Maus Unkonjugiert ELISA, WB SPAG6 monoclonal antibody (M01), clone 3E3 Western Blot analysis of SPAG6 expression in A-431 . Western Blot detection against Immunogen (37.11 KDa) . 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of SPAG6 expression in transfected 293T cell line by SPAG6 MaxPab polyclonal antibody.Lane 1: SPAG6 transfected lysate(55.50 KDa).Lane 2: Non-transfected lysate. 100 μg 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged SPAG6 is approximately 1ng/ml as a capture antibody. 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen HRP IHC (p), WB   100 μL 14 bis 21 Tage
$416.90
Details

Am meisten referenzierte anti-Sperm Associated Antigen 6 Antikörper

  1. Cow (Bovine) Polyclonal SPAG6 Primary Antibody für WB - ABIN2785513 : Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005 (PubMed)

Weitere Antikörper gegen Sperm Associated Antigen 6 Interaktionspartner

Human Sperm Associated Antigen 6 (SPAG6) Interaktionspartner

  1. Upregulation of SPAG6 is associated with Myelodysplastic Syndrome.

  2. These results demonstrate that SPAG6 silencing induces PTEN expression to regulate apoptosis though the PI3K/AKT pathway, indicating that SPAG6 may be a potential therapeutic target for myelodysplastic syndromes.

  3. SPAG6 and L1TD1 are tumor-specifically methylated in NSCLCs and that DNA methylation is involved in the transcriptional regulation of these genes. Moreover, in vitro as well as in vivo experiments revealed tumor-cell growth suppressing properties of L1TD1 in NSCLC cells.

  4. Study demonstrates that SPAG6 may regulate apoptosis through the TRAIL signal pathway by inhibiting the expression of FADD and the interactions between FADD and the TRAIL death receptors.

  5. studies demonstrate a role for Spag6 in the pathogenesis of OM in mice, possibly through its role in the regulation of cilia/basal body polarity through the PCP-dependent mechanisms in the middle ear and Eustachian tubes.

  6. These findings demonstrate that SPAG6 might have a role in malignant myeloid hematologic cell proliferation and apoptosis by regulating caspase proteins and p53, suggesting that SPAG6 may be a potential therapeutic target.

  7. SPAG6 is a S-SOX5 target gene, indicating a key role for S-SOX5 in the formation and function of motile cilia.

  8. Data describe the cloning of human and mouse Pf20 proteins that interact with Spag6 protein.

Mouse (Murine) Sperm Associated Antigen 6 (SPAG6) Interaktionspartner

  1. SPAG6 binds to prestin in vivo and contributes to fix prestin biomolecules in lateral plasma membrane of outer hair cells.

  2. SPAG6 is a S-SOX5 target gene, indicating a key role for S-SOX5 in the formation and function of motile cilia.

  3. Spag6 is essential for sperm flagellar motility and that it is important for the maintenance of the structural integrity of mature sperm. The occurrence of hydrocephalus in the mutant mice also implicates Spag6 in the motility of ependymal cilia.

  4. Data describe the cloning of human and mouse Pf20 proteins that interact with Spag6 protein.

  5. Accelerated mortality from hydrocephalus and pneumonia in mice with combined deficiency of Spag6 and Spag16L reveals a functional interrelationship between the two central apparatus proteins.

  6. Spag6 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.

Sperm Associated Antigen 6 (SPAG6) Antigen-Profil

Protein Überblick

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SPAG6

  • sperm associated antigen 6 (SPAG6) Antikörper
  • sperm associated antigen 6-like (Spag6l) Antikörper
  • sperm associated antigen 6 (Spag6) Antikörper
  • sperm associated antigen 6 (spag6) Antikörper
  • sperm associated antigen 6 L homeolog (spag6.L) Antikörper
  • DKFZp459D035 Antikörper
  • PF16 Antikörper
  • repro-sa-1 Antikörper
  • RGD1310892 Antikörper
  • SPAG6 Antikörper
  • zgc:91805 Antikörper

Bezeichner auf Proteinebene für SPAG6

axoneme central apparatus protein , protein PF16 homolog , sperm flagellar protein , sperm-associated antigen 6 , axoneme protein , sperm associated antigen 6

GENE ID SPEZIES
9576 Homo sapiens
50525 Mus musculus
360747 Rattus norvegicus
420505 Gallus gallus
431757 Danio rerio
450348 Pan troglodytes
477978 Canis lupus familiaris
539424 Bos taurus
548730 Xenopus (Silurana) tropicalis
734748 Xenopus laevis
100134839 Meleagris gallopavo
100174630 Pongo abelii
100286811 Sus scrofa
100724896 Cavia porcellus
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