anti-Sp7 Transcription Factor (SP7) Antikörper

SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Zusätzlich bieten wir Ihnen SP7 Kits (26) und SP7 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SP7 121340 Q8TDD2
SP7 300260  
SP7 170574 Q8VI67
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Top anti-SP7 Antikörper auf

Showing 10 out of 37 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-SP7 antibody (ARP32231_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Host: Rabbit <br /> Target Name: SP7 <br /> Sample Tissue: Jurkat Whole Cell lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Sp7 <br /> Sample Tissue: Rat Testis lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Osterix Polyclonal Antibody, Unconjugated (ABIN737811) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse spinal cord lysates probed with Osterix Polyclonal Antibody, unconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SP7 Antibody Titration: 2.5 ug/ml Positive Control: Jurkat Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Maus PE ICC, WB Western Blot (Negative): Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Experiment was done in reducing conditions. Immunocytochemistry/Immunofluorescence: Osterix/Sp7 Antibody (764704) [PE] [NBP2-47615PE] - Analysis in Saos-2 human osteosarcoma cell line. Specific staining was localized to nuclei. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged SP7 is approximately 1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert ELISA, IHC, WB 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage

SP7 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SP7 Antikörper

  1. Human Polyclonal SP7 Primary Antibody für IF (p), IHC (p) - ABIN737811 : Chen, Lazarenko, Zhang, Blackburn, Ronis, Badger: Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 (PubMed)
    Show all 11 Pubmed References

  2. Cow (Bovine) Polyclonal SP7 Primary Antibody für IHC, WB - ABIN2777381 : Milona, Gough, Edgar: Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells. in BMC genomics 2004 (PubMed)

Weitere Antikörper gegen SP7 Interaktionspartner

Human Sp7 Transcription Factor (SP7) Interaktionspartner

  1. Results showed that blocking miR (zeige MLXIP Antikörper)-31 led to an increase in osterix protein in both cell types at day 7, with an increase in osteocalcin (zeige BGLAP Antikörper) at day 21, suggesting MSC (zeige MSC Antikörper) osteogenesis

  2. Results provide evidence that CBP (zeige CREBBP Antikörper)-mediated acetylation and HDAC4 (zeige HDAC4 Antikörper)-mediated deacetylation have critical roles in the modification of Osx (zeige MID1 Antikörper), and thus are important in osteoblast differentiation.

  3. Osterix and RUNX2 (zeige RUNX2 Antikörper) are transcriptional regulators of sclerostin (zeige SOST Antikörper) in human bone

  4. Osterix decreased the chemosensitivity of breast cancer cells by upregulating the expression of GALNT14 (zeige GALNT14 Antikörper), which eventually suppressed the apoptosis of breast cancer cells.

  5. TP(thymidine phosphorylase (zeige TYMP Antikörper) ) curbed the expression of three proteins-IRF8 (zeige IRF8 Antikörper), RUNX2 (zeige RUNX2 Antikörper), and osterix. This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling and increased the methyltransferase DNMT3A's expression

  6. dissection of these interconnected epigenetic mechanisms that govern Sp7 gene activation reveals a hierarchical process where regulatory components mediating DNA demethylation play a leading role

  7. SP7 gene promoter is robustly enriched in epigenetic repressive marks that may explain its poor transcriptional response to osteoblast differentiating media in umbilical cord derived mesenchymal stem cells.

  8. Eight and five of the nine samples were negative for cell adhesion molecule 1 (zeige CADM1 Antikörper) and Osterix respectively. The other markers showed no statistical significance(CD151 (zeige CD151 Antikörper),ALP (zeige ALP Antikörper)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 (zeige CADM1 Antikörper) could be a useful marker for identifying this phenomenon in carcinoma tissues

  9. The results suggest that Osterix plays an important role in increasing BMP- 4 (zeige BMP4 Antikörper)-induced Cx43 (zeige GJA1 Antikörper) activity.

  10. The expression of specific targets Smad1 (zeige GARS Antikörper) and Osterix was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (zeige MUC7 Antikörper)+). As miR (zeige MLXIP Antikörper)-30b, miR (zeige MLXIP Antikörper)-133a, and miR (zeige MLXIP Antikörper)-143 are negatively regulated by Pi and restored by Mg(2 (zeige MUC7 Antikörper)+) with a congruent modulation of their known targets Runx2 (zeige RUNX2 Antikörper), Smad1 (zeige GARS Antikörper), and Osterix, our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

Zebrafish Sp7 Transcription Factor (SP7) Interaktionspartner

  1. In zebrafish lacking sp7, attachment bone is never present, independent of the stage of tooth development or fish age, yet replacement is not interrupted. There was abnormal orientation of teeth, and abnormal connection of pulp cavities of predecessor and replacement teeth, arrested dentinogenesis, non-polarization of odontoblasts and only a thin layer of dentin deposition.

  2. Sp7 plays a critical role in limiting the level of signaling and the rate of bone growth

  3. FGF and Wnt (zeige WNT2 Antikörper)/beta-Catenin (zeige CTNNB1 Antikörper) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.

  4. Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.

Mouse (Murine) Sp7 Transcription Factor (SP7) Interaktionspartner

  1. these findings strongly suggest that TGF-beta (zeige TGFB1 Antikörper) signaling plays a major role as one of the upstream regulators of Osx in cementoblast differentiation and cementum formation

  2. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 (zeige TGFBR2 Antikörper) signaling and that decreased bone volume in Osx-Cre;Tgfbr2 (zeige TGFBR2 Antikörper)(fl/fl (zeige FLT3LG Antikörper)) mice is likely due to fewer mature osteoblasts.

  3. DNA damage and senescence in osteoprogenitors expressing Osx may cause their decrease with age.

  4. The data support a model in which Dlx recruitment of Sp7 to osteoblast enhancers underlies Sp7-directed osteoblast specification.

  5. Mmp13 (zeige MMP13 Antikörper) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (zeige PTH Antikörper), and Osterix through distal enhancers.

  6. These results indicated that olfactory bulb development was not significantly impaired in the absence of Osx.

  7. Wnt3a (zeige WNT3A Antikörper) induces Osx expression via p38 MAPK (zeige MAPK14 Antikörper) signaling in dental follicle cells. Wnt3a (zeige WNT3A Antikörper)-induced Osx expression was inhibited in the presence of p38 mitogen-activated protein kinase (zeige MAPK14 Antikörper) (MAPK (zeige MAPK1 Antikörper)) inhibitors (SB203580 and SB202190) at gene and protein levels, as assessed by real-time PCR and immunocytohistochemistry, respectively.

  8. Transfection assay demonstrated that Osx was able to activate Bsp (zeige KLK6 Antikörper) promoter reporter in a dose-dependent manner. To define minimal region of Bsp (zeige KLK6 Antikörper) promoter activated by Osx, a series of deletion mutants of Bsp (zeige KLK6 Antikörper) promoter were generated, and the minimal region was narrowed down to the proximal 100 bp. Point-mutagenesis studies showed that one GC-rich (zeige RELB Antikörper) site was required for Bsp (zeige KLK6 Antikörper) promoter activation by Osx.

  9. OSX served a key role in the development and progression of ALD (zeige ABCD1 Antikörper)-induced VSMC calcification. This observation may aid in the explanation of the role of OSX in the pathogenesis of vascular calcification

  10. results suggest that expression of Sp7 during the early stage of Satb2 (zeige SATB2 Antikörper)-induced osteogenic differentiation of BMSCs is regulated by miR (zeige MLXIP Antikörper)-27a.

SP7 Antigen-Profil

Protein Überblick

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

Genbezeichner und Symbole assoziert mit SP7

  • Sp7 transcription factor (SP7) Antikörper
  • Sp7 transcription factor (Sp7) Antikörper
  • Sp7 transcription factor (sp7) Antikörper
  • uncharacterized LOC100063836 (LOC100063836) Antikörper
  • Sp7 transcription factor L homeolog (sp7.L) Antikörper
  • Sp7 transcription factor 7 (Sp7) Antikörper
  • 6430578P22Rik Antikörper
  • C22 Antikörper
  • OI11 Antikörper
  • OI12 Antikörper
  • osterix Antikörper
  • osx Antikörper
  • sp7 Antikörper

Bezeichner auf Proteinebene für SP7

transcription factor Sp7 , zinc finger protein osterix , osterix , transcription factor osterix , Sp7 transcription factor , transcription factor Sp7-like , trans-acting transcription factor 7 , Sp7 transcription factor 7

121340 Homo sapiens
300260 Rattus norvegicus
405789 Danio rerio
467004 Pan troglodytes
531995 Bos taurus
607857 Canis lupus familiaris
702575 Macaca mulatta
100063836 Equus caballus
100101324 Xenopus laevis
100189548 Xenopus (Silurana) tropicalis
100407102 Callithrix jacchus
100587177 Nomascus leucogenys
170574 Mus musculus
404701 Sus scrofa
100732690 Cavia porcellus
Ausgewählte Anbieter für anti-SP7 (SP7) Antikörper
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