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anti-SMCR8 Antikörper

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy.

3 Treffer:

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) Primary Antibody

SMCR8 Reaktivität: Human IF, IHC (p), WB Wirt: Kaninchen Polyclonal
Produktnummer ABIN5588427
$577.33
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (C-Term) Primary Antibody

SMCR8 Reaktivität: Hund, Pferd, Human, Kaninchen, Ratte WB Wirt: Kaninchen Polyclonal
Produktnummer ABIN2791916
$229.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 3 Werktagen

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (AA 841-890) Primary Antibody

SMCR8 Reaktivität: Human WB Wirt: Kaninchen Polyclonal
Produktnummer ABIN6753676
$551.83
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 14 Werktagen
  • Typ Primary
    • Primary
  • Target Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4 Molecule (CD4)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Albumin (ALB)
    • Interferon gamma (IFNG)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Heat Shock Protein 70 (HSP70)
    • CD44
    • Amyloid beta (A4) Precursor Protein (APP)
    • Tuberous Sclerosis 2 (TSC2)
    • Myc Proto-Oncogene protein (MYC)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD19 Molecule (CD19)
    • Histone H4
    • CD8a Molecule (CD8A)
    • Synuclein, alpha (SNCA)
    • Hemagglutinin (HA)
    • Integrin alpha M (ITGAM)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • CD5 Molecule (CD5)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Heat Shock 27kDa Protein 1 (HSPB1)
    • Mucin 1, Cell Surface Associated (MUC1)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Interleukin 2 (IL2)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD14
    • Activating Transcription Factor 2 (ATF2)
    • CD34
  • Anwendung
    • Western Blotting (WB)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Reaktivität
    • Human
    • Hund
    • Pferd
    • Kaninchen
    • Ratte
  • Abbildungen verfügbar
  • Wirt
    • Kaninchen
  • Klonalität
    • Polyclonal
  • Bindungsspezifität
    • AA 841-890
    • C-Term
  • Isotyp
    • IgG
  • Format
    • Liquid
    • Lyophilized

SMCR8 Antigen-Profil

Protein Überblick

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.

Genbezeichner und Symbole assoziert mit SMCR8

  • Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b) Antikörper
  • 2310076G09Rik Antikörper
  • AI642055 Antikörper
  • D030073L15Rik Antikörper
  • RGD1564621 Antikörper
  • smcr8 Antikörper

Bezeichner auf Proteinebene für SMCR8

Smith-Magenis syndrome chromosomal region candidate gene 8 protein , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog , Smith-Magenis syndrome chromosome region, candidate 8 homolog , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B , guanine nucleotide exchange protein smcr8b , smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog

GENE ID SPEZIES
140775 Homo sapiens
237782 Mus musculus
497918 Rattus norvegicus
407723 Danio rerio
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