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anti-SMCR8 Antikörper

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy.

3 Treffer:

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) Primary Antibody

SMCR8 Reaktivität: Human IF, IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5588427
$577.33
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (C-Term) Primary Antibody

SMCR8 Reaktivität: Human, Ratte, Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2791916
$389.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 3 Werktagen

anti-SMCR8 Antikörper (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (AA 841-890) Primary Antibody

SMCR8 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6753676
$551.83
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 14 Werktagen
  • Typ Primary
    • Primary
  • Target Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Albumin (ALB)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Myc Proto-Oncogene protein (MYC)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • CD44
    • CD8
    • Histone H4
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Jun Proto-Oncogene (JUN)
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD3
    • Synuclein, alpha (SNCA)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Androgen Receptor (AR)
    • CD14
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
  • Anwendung
    • Western Blotting (WB)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Reaktivität
    • Human
    • Hund
    • Pferd
    • Kaninchen
    • Ratte
  • Abbildungen verfügbar
  • Wirt
    • Kaninchen
  • Klonalität
    • Polyclonal
  • Bindungsspezifität
    • AA 841-890
    • C-Term
  • Isotyp
    • IgG
  • Format
    • Liquid
    • Lyophilized

SMCR8 Antigen-Profil

Protein Überblick

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.

Genbezeichner und Symbole assoziert mit SMCR8

  • Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8) Antikörper
  • Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b) Antikörper
  • 2310076G09Rik Antikörper
  • AI642055 Antikörper
  • D030073L15Rik Antikörper
  • RGD1564621 Antikörper
  • smcr8 Antikörper

Bezeichner auf Proteinebene für SMCR8

Smith-Magenis syndrome chromosomal region candidate gene 8 protein , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog , Smith-Magenis syndrome chromosome region, candidate 8 homolog , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B , guanine nucleotide exchange protein smcr8b , smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog

GENE ID SPEZIES
140775 Homo sapiens
237782 Mus musculus
497918 Rattus norvegicus
407723 Danio rerio

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