Signal-Regulatory Protein alpha (SIRPA) ELISA Kits

The protein encoded by SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen SIRPA Antikörper (217) und SIRPA Proteine (34) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SIRPA 140885 P78324
SIRPA 19261 P97797
SIRPA 25528 P97710
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top SIRPA ELISA Kits auf antikoerper-online.de

Showing 7 out of 19 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Maus 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$380.00
Details
Human < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   100 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$695.00
Details
Ratte < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Human < 0.056 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details

Weitere ELISA Kits für SIRPA Interaktionspartner

Human Signal-Regulatory Protein alpha (SIRPA) Interaktionspartner

  1. SIRP alpha protein is under-expressed in low and high-grades of astrocytoma from patients' brain samples.

  2. Anti-SIRPA antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

  3. SIRPalpha might play an important role in the progression of oral leukoplakia and oral cancer, and could be a pivotal therapeutic target in oral squamous cell carcinoma, regulating the phenotype of macrophages via targeting NF-kappaB (zeige NFKB1 ELISA Kits) signaling.

  4. TTI-621 (SIRPalphaFc) is a fully human recombinant fusion protein that blocks the CD47 (zeige CD47 ELISA Kits)-SIRPalpha axis by binding to human CD47 (zeige CD47 ELISA Kits) and enhancing phagocytosis of malignant cells..These data indicate that TTI-621 is active across a broad range of human tumors.

  5. data suggest that TTI-621 may be efficacious in triggering the destruction of cancer cells by a diverse population of TAMs found in vivo and support possible combination approaches to augment the activity of CD47 (zeige CD47 ELISA Kits) blockade

  6. CD47 (zeige CD47 ELISA Kits), TSP1 (zeige THBS1 ELISA Kits), and to a lesser extent SIRPalpha facilitate exosome-mediated myeloid-derived suppressor cells chemotaxis and migration.

  7. exploited by Hepatitis E virus to negative regulated IFN-beta (zeige IFNB1 ELISA Kits) of the host innate immune system to promote viral infection

  8. Data suggest a reduction in the CD47 antigen (zeige CD47 ELISA Kits)/signal-regulatory protein alpha (SIRPalpha) pathway by programmed cell death protein 1 (PD-1 (zeige PDCD1 ELISA Kits)) blockade, which regulates Myeloid-derived suppressor cells (MDSCs) and tumor associated macrophages (TAMs).

  9. agents that block the CD47 (zeige CD47 ELISA Kits):SIRP-alpha engagement are attractive therapeutic targets as a monotherapy or in combination with additional immune-modulating agents for activating antitumor T cells in vivo

  10. the data suggest that combinatorial actions of ADAM10 (zeige ADAM10 ELISA Kits) and gamma-secretase on SIRPalpha cleavage promote inflammatory signaling.

Mouse (Murine) Signal-Regulatory Protein alpha (SIRPA) Interaktionspartner

  1. Anti-SIRPA antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

  2. SIRPalpha-expressing dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF (zeige TNF ELISA Kits) receptor ligands in the adult mouse spleen.

  3. CCR7 (zeige CCR7 ELISA Kits) deficiency results in apoptosis of Sirpa- dendritic cells, which is counterbalanced by expansion of immature Sirpa+ dendritic cells that efficiently induce Treg generation.

  4. Mechanistic studies suggest a PKC (zeige PKC ELISA Kits)-Syk (zeige SYK ELISA Kits)-mediated signaling pathway, to which IL-10 (zeige IL10 ELISA Kits) conversely inhibits, is required for activating macrophage self-targeting, followed by phagocytosis independent of calreticulin (zeige CALR ELISA Kits) Moreover, we identified spleen red pulp to be one specific tissue that provides stimuli constantly activating macrophage phagocytosis albeit lacking in Cd47 (zeige CD47 ELISA Kits)(-/-) or Sirpalpha(-/-) mice.

  5. these findings have demonstrated how tumor cells inhibit innate sensing in dendritic cells and suggested that the CD47 (zeige CD47 ELISA Kits)-SIRPalpha axis is critical for dendritic cell-driven antitumor immunity

  6. Data provide evidence that SIRPalpha-mediated phagocytosis is not a major determinant in prion (zeige PRNP ELISA Kits) disease pathogenesis.

  7. Treg cells protect dopaminergic neurons against MPP (zeige MPZ ELISA Kits)+ neurotoxicity by a cell-to-cell contact mechanism underlying CD47 (zeige CD47 ELISA Kits)-SIRPA interaction and Rac1/Akt (zeige AKT1 ELISA Kits) activation.

  8. In conclusion, our data suggest that SIRPalpha signaling through SHP-2 (zeige PTPN11 ELISA Kits)-PI3K-Akt2 (zeige AKT2 ELISA Kits) strongly influences osteoblast differentiation from bone marrow stromal cells.

  9. These results indicate an important role for CD47 (zeige CD47 ELISA Kits)-SIRPalpha interactions in innate control of malaria and suggest novel targets for intervention.

  10. TLR5 (zeige TLR5 ELISA Kits) mediates CD172a(+) intestinal lamina propria dendritic cell induction of Th17 cells.

SIRPA Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

Genbezeichner und Symbole assoziert mit SIRPA

  • signal regulatory protein alpha (SIRPA) Antikörper
  • signal-regulatory protein alpha (SIRPA) Antikörper
  • tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039) Antikörper
  • tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378) Antikörper
  • tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224) Antikörper
  • signal-regulatory protein alpha (Sirpa) Antikörper
  • AI835480 Antikörper
  • Bit Antikörper
  • CD172a Antikörper
  • MFR Antikörper
  • MYD-1 Antikörper
  • P84 Antikörper
  • Ptpns1 Antikörper
  • SHP-1 Antikörper
  • SHPS-1 Antikörper
  • SHPS1 Antikörper
  • SIRP Antikörper
  • SIRP-A1 Antikörper
  • SIRP-B1 Antikörper
  • SIRPA Antikörper
  • swc3 Antikörper

Bezeichner auf Proteinebene für SIRPA

CD172 antigen-like family member A , brain-immunoglobulin-like molecule with tyrosine-based activation motifs , inhibitory receptor SHPS-1 , macrophage fusion receptor , myd-1 antigen , tyrosine phosphatase SHP substrate 1 , tyrosine-protein phosphatase non-receptor type substrate 1 , MyD-1 antigen , SHP substrate 1 , SHPS-1 , protein tyrosine phosphatase, non-receptor type substrate 1 , signal-regulatory protein alpha-1 , sirp-alpha-1 , signal-regulatory protein alpha , signal regulatory protein alpha , tyrosine-protein phosphatase non-receptor type substrate 1-like , brain Ig-like molecule with tyrosine-based activation motifs , brain immunological-like with tyrosine-based motifs , mSIRP-alpha1 , myD-1 antigen , Brain immunoglobulin like protein with tyrosine - based activation motifs , Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1) , Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1) , macrophage membrane protein MFP150 , swine workshop cluster 3 antigen

GENE ID SPEZIES
140885 Homo sapiens
327666 Bos taurus
419267 Gallus gallus
458039 Pan troglodytes
609452 Canis lupus familiaris
717811 Macaca mulatta
100067339 Equus caballus
100351485 Oryctolagus cuniculus
100400378 Callithrix jacchus
100456232 Pongo abelii
100590224 Nomascus leucogenys
19261 Mus musculus
25528 Rattus norvegicus
494566 Sus scrofa
Ausgewählte Anbieter für SIRPA (SIRPA) ELISA Kits
Haben Sie etwas anderes gesucht?