Sialic Acid Binding Ig-Like Lectin 9 Proteine (SIGLEC9)

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Zusätzlich bieten wir Ihnen SIGLEC9 Antikörper (173) und SIGLEC9 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIGLEC9 27180 Q9Y336
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Top SIGLEC9 Proteine auf

Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Baculovirus infected Insect Cells Human hIgG-His-tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human SIGLEC9 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
Human Human Fc Tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
Mammalian Cells Human Fc Tag   50 μg Anmelden zum Anzeigen 4 Days

SIGLEC9 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , ,

Weitere Proteine zu Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) Interaktionspartnern

Human Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) Interaktionspartner

  1. The SIGLEC9 rs2075803 G/rs2258983 A haplotype, which corresponds to a Siglec-9 variant that is less effective at suppressing inflammatory response, may be a risk factor for the development of emphysema.

  2. Glycophorin A (zeige GYPA Proteine), the most abundant sialoglycoprotein on erythrocytes, engaged neutrophil Siglec-9, a sialic acid-recognizing receptor known to dampen innate immune cell activation. These studies demonstrate a previously unsuspected role for erythrocytes in suppressing neutrophils ex vivo and in vitro and help explain why neutrophils become easily activated after separation from whole blood.

  3. Data suggest that sialic acid-binding Ig-like lectin-9 (Siglec-9)may serve as a potential diagnostic and therapeutic target for rheumatoid arthritis (RA).

  4. The mechanism of the Siglec-9 and AOC3 (zeige AOC2 Proteine) interaction is mediated both by protein-sugar interactions via the V domain and by the protein-protein interactions via the C22 Siglec9 domain.

  5. This work defines a critical role for aberrantly glycosylated MUC1 (zeige MUC1 Proteine) and identifies an activating pathway that follows engagement of Siglec-9.

  6. Constitutively expressed Siglec-9 inhibits LPS (zeige IRF6 Proteine)-induced CCR7 (zeige CCR7 Proteine), but enhances IL-4 (zeige IL4 Proteine)-induced CD200R (zeige CD200R1 Proteine) expression in human macrophages.

  7. Ligands for Siglec-8 (zeige SIGLEC8 Proteine) and Siglec-9 may regulate the function of eosinophils, mast cells, neutrophils, and other cells in sinus mucosa.

  8. Inflammation results in up-regulation of immuneinhibitory Siglec-8 (zeige SIGLEC8 Proteine) and Siglec-9 sialoglycan ligands on human airways.

  9. a polymorphism that reduced Siglec-9 binding to carcinomas was associated with improved early survival in non-small-cell lung cancer patients

  10. Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3 (zeige CD33 Proteine).

Chimpanzee Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) Interaktionspartner

  1. Binding studies on recombinant human Siglec-9 show recognition of both Neu5Ac and Neu5Gc; in striking contrast, chimpanzee and gorilla Siglec-9 strongly prefer binding Neu5Gc.

SIGLEC9 Protein Überblick

Protein Überblick

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Genbezeichner und Symbole assoziert mit SIGLEC9

  • sialic acid binding Ig like lectin 9 (SIGLEC9)
  • sialic acid-binding immunoglobulin-like lectin 9 (SIGLEC9)
  • CD329 Protein
  • CDw329 Protein
  • FOAP-9 Protein
  • OBBP-LIKE Protein
  • siglec-9 Protein
  • siglec9 Protein

Bezeichner auf Proteinebene für SIGLEC9

protein FOAP-9 , sialic acid-binding Ig-like lectin 9 , sialic acid-binding immunoglobulin-like lectin 9 , sialic acid binding Ig-like lectin 9

27180 Homo sapiens
497116 Pan troglodytes
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