Sec23 Homolog A (S. Cerevisiae) Proteine (SEC23A)

The protein encoded by SEC23A is a member of the SEC23 subfamily of the SEC23/SEC24 family. Zusätzlich bieten wir Ihnen SEC23A Antikörper (44) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SEC23A 20334 Q01405
Ratte SEC23A SEC23A 58817  
SEC23A 10484 Q15436
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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SEC23A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Sec23 Homolog A (S. Cerevisiae) (SEC23A) Interaktionspartnern

Mouse (Murine) Sec23 Homolog A (S. Cerevisiae) (SEC23A) Interaktionspartner

  1. these data demonstrate an equivalent function for SEC23A/B, with evolutionary shifts in the transcription program likely accounting for the distinct phenotypes of SEC23A/B deficiency within and across species, a paradigm potentially applicable to other sets of paralogous genes.

  2. This study also validated the interaction between HAP1 and Sec23A using co-immunoprecipitation experiments with endogenous proteins. This manuscript also reports on the high confidence interacting partners of HAP1 identified by the non-biased approach used in this study, which interestingly, consists of predominantly trafficking-related proteins

  3. results suggest that mammalian SEC23A and SEC23B transport overlapping yet distinct spectra of cargo in vivo

  4. Sec23a contains consensus TFII-I binding sites in the proximal promoters; the chromatin immunoprecipitation analysis showed that TFII-I transcription factors are recruited to these sites in vivo in Williams-Beuren syndrome.

  5. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.

Zebrafish Sec23 Homolog A (S. Cerevisiae) (SEC23A) Interaktionspartner

  1. sec23b is an essential component of the cartilage extracellular matrix secretory pathway in chondrocytes

Human Sec23 Homolog A (S. Cerevisiae) (SEC23A) Interaktionspartner

  1. This larger GWAS yields two loci harboring genome-wide significant variants affecting serum 25-hydroxyvitamin D levels (P = 4.7x10(-9) at rs8018720 in SEC23A, and P = 1.9x10(-14) at rs10745742 in AMDHD1).

  2. these data demonstrate an equivalent function for SEC23A/B, with evolutionary shifts in the transcription program likely accounting for the distinct phenotypes of SEC23A/B deficiency within and across species, a paradigm potentially applicable to other sets of paralogous genes.

  3. Mutation on serine207 of Sec23A protein changes Unc-51 like kinase 1(ULK 1) targeted phosphorylation. During elevated autophagy, induced by amino acid starvation, rapamycin, or overexpression of ULK1,phosphorylation of Sec23A reduced the interaction between vesicular transport proteins Sec23A and Sec31A.

  4. Data indicate that vesicular transport protein SEC23A as a target of miR-375.

  5. findings suggest that miR-21 promoted proliferation, migration, and invasion of colorectal cancer cells in vitro by down regulating the expression of Sec23A

  6. miR-375 is involved in development of chemo-resistance to docetaxel through regulating SEC23A and YAP1 expression.

  7. ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.

  8. Hypomorphic mutations of SEC23B gene account for mild phenotypes of congenital dyserythropoietic anemia type II.

  9. show that membrane association of COPII components, and in particular of Sec23a, is impaired by ER stress-inducing agents suggesting the existence of a dynamic interplay between protein folding and COPII assembly at the ER

  10. Data indicate that a synthetic polypeptide containing the N terminus of bovine AE1 bound the Sec23A-Sec24C complex through a selective interaction with Sec24C.

  11. the BBF2H7-mediated Sec23A pathway is required for ER-to-Golgi procollagen trafficking to promote collagen synthesis

  12. Sec23A overexpression reduced cell growth but did not induce apoptosis, whereas inhibition of Sec23A stimulated cell proliferation

  13. When entering into mitosis, the COPII component Sec24Cp is simultaneously deglycosylated and phosphorylated; however, Sec23A is not.

  14. Sec23A mutation causes cranio-lenticulo-sutural dysplasia, and disrupts the nucleation of COPII coat proteins at endoplasmic reticulum exit sites.

  15. Data show that coupling of the Sec23/24 and Sec13/31 layers of the COPII coat is required to drive export of collagen from the endoplasmic reticulum, and that efficient COPII assembly is essential for normal craniofacial development during embryogenesis.

SEC23A Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.

Genbezeichner und Symbole assoziert mit SEC23A

  • SEC23 homolog A, COPII coat complex component (Sec23a)
  • Sec23 homolog A, coat complex II component (Sec23a)
  • Sec23 homolog A, COPII coat complex component (sec23a)
  • Sec23 homolog A, coat complex II component (SEC23A)
  • protein transport protein Sec23A (LOC576977)
  • Sec23 homolog A, COPII coat complex component S homeolog (sec23a.S)
  • COP-II coat subunit (SEC23A)
  • protein transport protein Sec23A (LOC100183335)
  • CLSD Protein
  • DKFZp459O136 Protein
  • Msec23 Protein
  • sec23a Protein
  • Sec23r Protein
  • wu:fc10f08 Protein
  • wu:fi15g03 Protein
  • zgc:55534 Protein

Bezeichner auf Proteinebene für SEC23A

SEC23-related protein A , protein transport protein Sec23A , SEC23A , cru , crusher , Sec23 homolog A (S. cerevisiae) , Sec23 homolog A , COP-II coat subunit , protein transport protein Sec23A-like

GENE ID SPEZIES
20334 Mus musculus
58817 Rattus norvegicus
406774 Danio rerio
423335 Gallus gallus
452871 Pan troglodytes
480295 Canis lupus familiaris
533994 Bos taurus
576977 Strongylocentrotus purpuratus
698500 Macaca mulatta
779038 Xenopus laevis
780116 Xenopus (Silurana) tropicalis
5728475 Chlamydomonas reinhardtii
100077829 Ornithorhynchus anatinus
100155766 Sus scrofa
100173678 Pongo abelii
100183335 Ciona intestinalis
100413347 Callithrix jacchus
100477454 Ailuropoda melanoleuca
100604770 Nomascus leucogenys
10484 Homo sapiens
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