anti-Scavenger Receptor Class B, Member 2 (SCARB2) Antikörper

The protein encoded by SCARB2 is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Zusätzlich bieten wir Ihnen SCARB2 Proteine (14) und SCARB2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SCARB2 950 Q14108
SCARB2 12492 O35114
SCARB2 117106 P27615
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Top anti-SCARB2 Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Chinese Hamster Kaninchen Unkonjugiert ICC, FACS, IF, IHC (p), IHC, WB Detection of SR-BII in Jurkat whole cell lysate using ABIN152881. Lane 1: 1:1000 Lane 2: 1:500 Lane 3: 1:100 Western Blot: SR-BII Antibody [ABIN152881] - Western blot analysis of SR-BII in 1. Human heart lysate 2. Mouse heart lysate 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Ziege Unkonjugiert IHC, ELISA, WB EB09295 (0.1µg/ml) staining of Human Cerebral Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Hund Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, WB Staining of LIMP II in rat infarctzone tissue using ABIN152898 with a DAB detection system. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$473.81
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged SCARB2 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: LIMPII/SR-B2 Antibody [NBP1-28914] - (3.8ug/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$466.62
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details

SCARB2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SCARB2 Antikörper

  1. Chinese Hamster Polyclonal SCARB2 Primary Antibody für ICC, FACS - ABIN152881 : Huby, Doucet, Dachet, Ouzilleau, Ueda, Afzal, Rubin, Chapman, Lesnik: Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues. in The Journal of clinical investigation 2006 (PubMed)
    Show all 12 Pubmed References

  2. Dog (Canine) Polyclonal SCARB2 Primary Antibody für ICC, IF - ABIN152898 : Balreira, Gaspar, Caiola, Chaves, Beirão, Lima, Azevedo, Miranda: A nonsense mutation in the LIMP-2 gene associated with progressive myoclonic epilepsy and nephrotic syndrome. in Human molecular genetics 2008 (PubMed)
    Show all 10 Pubmed References

  3. Human Polyclonal SCARB2 Primary Antibody für ELISA, WB - ABIN1002736 : Fujita, Ezaki, Noguchi, Kono, Himeno, Kato: Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein in rat liver lysosomal membranes. in Biochemical and biophysical research communications 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal SCARB2 Primary Antibody für IHC, ELISA - ABIN361195 : Murphy, Gysbers, Abbott, Tayebi, Kim, Sidransky, Cooper, Garner, Halliday: Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease. in Brain : a journal of neurology 2014 (PubMed)

  5. Human Polyclonal SCARB2 Primary Antibody für IHC (p), IHC - ABIN449974 : Berkovic, Dibbens, Oshlack, Silver, Katerelos, Vears, Lüllmann-Rauch, Blanz, Zhang, Stankovich, Kalnins, Dowling, Andermann, Andermann, Faldini, DHooge, Vadlamudi, Macdonell, Hodgson, Bayly, Savige et al.: Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. ... in American journal of human genetics 2008 (PubMed)

Weitere Antikörper gegen SCARB2 Interaktionspartner

Zebrafish Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. This work describes a novel function for the Scarb2 receptor as an essential glycoprotein for notochord development.

Human Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.

  2. The findings identify SR-BII as a functional SAA (zeige SAA1 Antikörper) receptor that mediates SAA (zeige SAA1 Antikörper) uptake and contributes to its proinflammatory signaling via the MAPK (zeige MAPK1 Antikörper)-mediated signaling pathways.

  3. In this paper we provide an updated overview of the clinical and genetic features of SCARB2-related PME (zeige CSTB Antikörper) and on the functions of the LIMP2 protein [review]

  4. neutrophils are able to drive a macrophage activation that would regulate the increase in LIMP-2 expression during the early phase of Cer (zeige CBLN1 Antikörper)-induced acute pancreatitis

  5. Findings suggested that STX1B (zeige STX1B Antikörper) rs4889603, FAM47E rs6812193 and SCARB2 rs6825004 do not confer a significant risk for Parkinson's disease

  6. LIMPII was increased greater than twofold in urinary microvesicles obtained from patients with idiopathic membranous nephropathy compared to microvesicles of patients with idiopathic focal segmental glomerulosclerosis and normal controls.

  7. hSR-BII (zeige CACNA1E Antikörper), and to a lesser extent hSR-BI, significantly increase LPS (zeige IRF6 Antikörper)-induced inflammation and contribute to LPS (zeige IRF6 Antikörper)-induced tissue injury in the liver and kidney, two major organs susceptible to LPS (zeige IRF6 Antikörper) toxicity.

  8. Although hrGCase cellular uptake is independent of LIMP-2, its trafficking to the lysosomes is mediated by this receptor.

  9. SNCA and SCARB2 loci are also associated with dementia with Lewy bodies, after a study-wise Bonferroni correction, although these have a different association profile than the associations reported for the same loci in Parkinson's.

  10. a novel mutation in SCARB2 as a cause of progressive myoclonus epilepsy in China

Mouse (Murine) Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. The findings identify SR-BII as a functional SAA (zeige SAA1 Antikörper) receptor that mediates SAA (zeige SAA1 Antikörper) uptake and contributes to its proinflammatory signaling via the MAPK (zeige MAPK1 Antikörper)-mediated signaling pathways.

  2. AP-3 (zeige AP3B1 Antikörper)-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 (zeige PRDX6 Antikörper) in vitro and in vivo

  3. Heterologous expression of the luminal domain of LIMP-2 in wild-type cells.

  4. In LIMP-2-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein accumulation.

  5. absence of Limp-2 reduces inflammation in experimental crescentic glomerulonephritis with decreased macrophage and T-cell infiltration in the kidney.

  6. Limp-2 deficiency leads to a minor increase in circulating renin (zeige REN Antikörper). Limp-2, however, is not required for acute or chronic stimulation of renin (zeige REN Antikörper) release.

  7. The SR-BII is involved in cholesterol ester uptake for steroidogenesis and spermatogenesis in the testis.

  8. The residues between 144 and 151 are critical for SCARB2 binding to VP1 of EV71 and seven residues from the human receptor could convert murine SCARB2, an otherwise inefficient receptor, to an efficient receptor for EV71 viral infection.

  9. The data suggest that tubular proteinuria in Limp-2(-/-) mice is due to failure of endosomes containing reabsorbed proteins to fuse with lysosomes in the proximal tubule of the kidney. Failure of proteolysis is a novel mechanism for tubular proteinuria.

  10. The coiled-coil structure of LIMP-2 is required for its interaction with beta-glucocerebrosidase (zeige GBA Antikörper).

SCARB2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SCARB2

  • scavenger receptor class B, member 2a (scarb2a) Antikörper
  • scavenger receptor class B member 2 (SCARB2) Antikörper
  • scavenger receptor class B member 2 (scarb2) Antikörper
  • scavenger receptor class B, member 2 (Scarb2) Antikörper
  • 9330185J12Rik Antikörper
  • AMRF Antikörper
  • Cd36l2 Antikörper
  • chunp6914 Antikörper
  • EPM4 Antikörper
  • fi13c07 Antikörper
  • HLGP85 Antikörper
  • LGP85 Antikörper
  • LIMP-2 Antikörper
  • LimpII Antikörper
  • MLGP85 Antikörper
  • scarb2 Antikörper
  • SR-BII Antikörper
  • wu:fi13c07 Antikörper

Bezeichner auf Proteinebene für SCARB2

CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 , CD36 antigen-like 2 , lysosome membrane protein 2 , scavenger receptor class B, member 2 , lysosome membrane protein 2-like , putative lysosomal integral membrane protein II , 85 kDa lysosomal membrane sialoglycoprotein , 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2 , CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) , LIMP II , lysosome membrane protein II

GENE ID SPEZIES
192340 Danio rerio
422638 Gallus gallus
461239 Pan troglodytes
549311 Xenopus (Silurana) tropicalis
699990 Macaca mulatta
100026052 Monodelphis domestica
100455864 Pongo abelii
100190617 Taeniopygia guttata
100397594 Callithrix jacchus
100470627 Ailuropoda melanoleuca
100593903 Nomascus leucogenys
533177 Bos taurus
950 Homo sapiens
12492 Mus musculus
117106 Rattus norvegicus
478435 Canis lupus familiaris
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