SUMO1/sentrin Specific Peptidase 5 Proteine (SENP5)

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for numerous biologic processes. Zusätzlich bieten wir Ihnen SENP5 Antikörper (107) und SENP5 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SENP5 205564 Q96HI0
Ratte SENP5 SENP5 303874  
SENP5 320213 Q6NXL6
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Top SENP5 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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SENP5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu SUMO1/sentrin Specific Peptidase 5 (SENP5) Interaktionspartnern

Human SUMO1/sentrin Specific Peptidase 5 (SENP5) Interaktionspartner

  1. Results from a study on gene expression variability markers in early-stage human embryos shows that SENP5 is a putative expression variability marker for the 3-day, 8-cell embryo stage.

  2. Mild oxidative stress stabilized the SENP5 protein in the oral squamous cell carcinoma cells, and only the combination of SENP5 silencing and H2O2 application led to mitochondria fragmentation and a significant increase in cell apoptosis.

  3. Low expression of SENP5 is associated with good prognosis among breast cancer patients.

  4. Knockdown of SENP5 resulted in increased levels of SUMO-1 (zeige SUMO1 Proteine) and SUMO-2 (zeige SUMO2 Proteine)/3, inhibition of cell proliferation, defects in nuclear morphology, and appearance of binucleate cells, revealing an essential role for SENP5 in mitosis and/or cytokinesis.

  5. altered subcellular localization of SENP5 in oral squamous cell carcinoma (OSCC) cells and the correlation between SENP5 expression and the differentiation of OSCC.

  6. Nucleolar protein (zeige MCRS1 Proteine) B23/nucleophosmin (zeige NPM1 Proteine) regulates the vertebrate SUMO pathway through SENP3 (zeige ULP1 Proteine) and SENP5 proteases.

SENP5 Protein Überblick

Protein Überblick

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006

Genbezeichner und Symbole assoziert mit SENP5

  • SUMO1/sentrin specific peptidase 5 (SENP5)
  • SUMO1/sentrin specific peptidase 5 (Senp5)
  • SUMO/sentrin specific peptidase 5 (Senp5)
  • SUMO1/sentrin specific peptidase 5 (senp5)
  • SUMO1/sentrin specific peptidase 5 L homeolog (senp5.L)
  • 6230429P13Rik Protein
  • A730063F07Rik Protein
  • AI851888 Protein
  • BB189556 Protein
  • senp5 Protein
  • SMT3IP3 Protein

Bezeichner auf Proteinebene für SENP5

SUMO1/sentrin specific protease 5 , sentrin-specific protease 5 , sentrin/SUMO-specific protease SENP5 , SUMO/sentrin specific protease 5 , Sumo1/sentrin/SMT3 specific peptidase 5 , SUMO/Smt3-specific isopeptidase 3 , SUMO1/sentrin specific peptidase 5 , sentrin/SUMO-specific protease 5 , sentrin-specific protease 5-like

GENE ID SPEZIES
205564 Homo sapiens
303874 Rattus norvegicus
320213 Mus musculus
424955 Gallus gallus
471052 Pan troglodytes
488033 Canis lupus familiaris
570299 Danio rerio
100021128 Monodelphis domestica
100069684 Equus caballus
100144689 Xenopus (Silurana) tropicalis
100192354 Xenopus laevis
100404948 Callithrix jacchus
100441890 Pongo abelii
100472846 Ailuropoda melanoleuca
100526077 Sus scrofa
100601928 Nomascus leucogenys
100298192 Bos taurus
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