SUMO/sentrin Specific Peptidase Family Member 8 Proteine (SENP8)

SENP8 encodes a cysteine protease that is a member of the sentrin-specific protease family. Zusätzlich bieten wir Ihnen SUMO/sentrin Specific Peptidase Family Member 8 Antikörper (70) und SUMO/sentrin Specific Peptidase Family Member 8 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SENP8 71599 Q9D2Z4
SENP8 123228 Q96LD8
SENP8 315723 Q5FVJ8
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Top SUMO/sentrin Specific Peptidase Family Member 8 Proteine auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
$394.90
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Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$115.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,539.17
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Hefe Arabidopsis thaliana His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
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Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$100.00
Details

SENP8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
, , ,
Rat (Rattus)

Weitere Proteine zu SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Interaktionspartnern

Arabidopsis thaliana SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Interaktionspartner

  1. DENEDDYLASE1 functions to maintain NEDD8 pathway activity by recovering diverted NEDD8 moieties from proteins of the NEDD8 conjugation machinery. [DEN1]

  2. mutants of a DEN1 homolog from Arabidopsis thaliana have no detectable defects in NEDD8 processing but do accumulate a broad range of NEDD8 conjugates. Neddylation may serve as a regulatory mechanism for cullin and non-cullin proteins. [DEN1]

Human SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Interaktionspartner

  1. Furthermore, the authors characterized SENP8/DEN1 as the protease that counteracts Ubc12 (zeige ube2m Proteine) auto-neddylation, and observed aberrant neddylation of Ubc12 (zeige ube2m Proteine) and other NEDD8 (zeige NEDD8 Proteine) conjugation pathway components in SENP8-deficient cells.

  2. In endothelial dysfunction, HDAC2 (zeige HDAC2 Proteine) levels were reciprocally regulated by ectopic expression of NEDD8 (zeige NEDD8 Proteine) and the de-NEDDylating enzyme SENP8.

  3. the expression of SENP8, SAE1 (zeige SAE1 Proteine), PIAS1 (zeige PIAS1 Proteine), PIAS2 (zeige PIAS2 Proteine) and ZMIZ1 is deregulated in the majority of PTC (zeige F9 Proteine) tissues, likely contributing to the PTC (zeige F9 Proteine) phenotype.

  4. Data indicate that overexpression of SENP8, a NEDD8 (zeige NEDD8 Proteine)-specific cysteine protease (zeige CTSB Proteine), resulted in deNEDDylation of E2F1 (zeige E2F1 Proteine) and promoted its transactivation activity at the p73 (zeige TP73 Proteine) gene.

  5. We analyzed whether CSN1 (zeige CSN1S1 Proteine) alone can increase DEN1 degradation in HeLa cells.these data suggest that the COP9 (zeige COPS8 Proteine) signalosome supports proteasome-dependent protein degradation of DEN1/DenA in fungi and in human cells.

  6. A role for SENP8 as a central regulator of the inflammatory process is identified using knockdown and overexpression approaches.

  7. the specificity of NEDD8 (zeige NEDD8 Proteine)-specific peptidase SENP8

  8. Data show that the stability of MDM2 (zeige MDM2 Proteine) is regulated by NEDD8 (zeige NEDD8 Proteine) pathway and identify NEDP1 that deneddylates MDM2 (zeige MDM2 Proteine), resulting in MDM2 (zeige MDM2 Proteine) destabilization concomitant with p53 (zeige TP53 Proteine) activation.

  9. NEDP1 is likely to play an important role in ubiquitin-mediated proteolysis by controlling the activity of SCF (zeige KITLG Proteine) complexes

  10. results suggest a unique role for NEDD8-specific protease 1(DEN1) in regulating the modification of cullin 1 (zeige CUL1 Proteine) by Nedd8 (zeige NEDD8 Proteine) protein

SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Protein Überblick

Protein Überblick

This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit SENP8

  • SUMO/sentrin peptidase family member, NEDD8 specific L homeolog (senp8.L)
  • Cysteine proteinases superfamily protein (AT5G60190)
  • SUMO/sentrin specific peptidase 8 (Senp8)
  • SUMO/sentrin peptidase family member, NEDD8 specific (SENP8)
  • SUMO/sentrin peptidase family member, NEDD8 specific (Senp8)
  • 9130010J17Rik Protein
  • AU020827 Protein
  • DEN1 Protein
  • F15L12.8 Protein
  • F15L12_8 Protein
  • MGC84956 Protein
  • NEDP1 Protein
  • PRSC2 Protein

Bezeichner auf Proteinebene für SENP8

SUMO/sentrin specific peptidase family member 8 , NEDD8-specific protease 1 , SUMO/sentrin specific protease 8 , SUMO/sentrin specific protease family member 8 , deneddylase-1 , protease, cysteine, 2 (NEDD8 specific) , sentrin-specific protease 8 , sentrin/SUMO-specific protease SENP8 , NEDD8 specific-protease cysteine 2 , SUMO sentrin specific protease family member 8 , deneddylase 1 , protease, cysteine 2 , SUMO/sentrin specific peptidase 8 , Sumo1/sentrin/SMT3 specific peptidase 8

GENE ID SPEZIES
735058 Xenopus laevis
836141 Arabidopsis thaliana
71599 Mus musculus
123228 Homo sapiens
315723 Rattus norvegicus
487631 Canis lupus familiaris
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