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SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Zusätzlich bieten wir Ihnen SOX17 Proteine (4) und SOX17 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 91 products:
Human Monoclonal SOX17 Primary Antibody für BI, IF - ABIN967681
DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: Efficient differentiation of human embryonic stem cells to definitive endoderm. in Nature biotechnology 2005
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Human Polyclonal SOX17 Primary Antibody für FACS - ABIN4895920
Bernardo, Faial, Gardner, Niakan, Ortmann, Senner, Callery, Trotter, Hemberger, Smith, Bardwell, Moffett, Pedersen: BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. in Cell stem cell 2011
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Human Polyclonal SOX17 Primary Antibody für ICC, IF - ABIN4355356
Schröter, Sleegers, Van Cauwenberghe, Bohndorf, Wruck, Van Broeckhoven, Adjaye: Lymphoblast-derived integration-free iPSC lines from a female and male Alzheimer's disease patient expressing different copy numbers of a coding CNV in the Alzheimer risk gene CR1. in Stem cell research 2016
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Dog (Canine) Monoclonal SOX17 Primary Antibody für IF, IHC - ABIN2452377
Bode, Barghorn, Fritzsche, Riener, Kristiansen, Knuth, Moch: MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011
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Dog (Canine) Polyclonal SOX17 Primary Antibody für IHC, WB - ABIN2781184
Zhang, Glöckner, Guo, Machida, Wang, Easwaran, Van Neste, Herman, Schuebel, Watkins, Ahuja, Baylin: Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. in Cancer research 2008
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Human Polyclonal SOX17 Primary Antibody für ELISA - ABIN451622
Kim, Saunders, Morrison: Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. in Cell 2007
Human Monoclonal SOX17 Primary Antibody für FACS, IF - ABIN2452673
Takeuchi, Nakatsuji, Suemori: Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. in Scientific reports 2014
The combination of methylated SOX17 with cytology better predicted neoplastic grade than cytology alone
SOX17 acts as a tumor suppressor in cholangiocarcinoma and its genetic, molecular and/or pharmacological restoration may represent a new promising therapeutic strategy.
Our results suggest that decreasing SOX17 levels may promote EC development and progression, and that by downregulating MAML3 (zeige MAML3 Antikörper) expression and Wnt (zeige WNT2 Antikörper) signaling, SOX17 acts as a tumor suppressor that may improve outcome in patients with EC.
SOX2 (zeige SOX2 Antikörper) repression in TCam-2 cells can be abrogated by recruitment of the constitutively expressed H3K27 demethylase (zeige MBD2 Antikörper) UTX (zeige KDM6A Antikörper) to the SOX2 (zeige SOX2 Antikörper) promoter through retinoid signaling, leading to expression of neuronal and other lineage genes. SOX17 has been shown to initiate human PGC (zeige PGC Antikörper) specification, with its target PRDM1 (zeige PRDM1 Antikörper) suppressing mesendodermal genes
Dedifferentiation of fibroblasts to CD34 (zeige CD34 Antikörper)(+) progenitor cells gives rise to endothelial cells and erythroblasts in a SOX17-dependent manner.
Study extracted and analyzed the experimentally validated 3D models of SOX17-HMG (zeige SSRP1 Antikörper) domain and beta-catenin (zeige CTNNB1 Antikörper); the molecular level disturbance in the two essential human proteins upon M76A and G103R mutation of SOX17, which further hampers the cell signaling phenomena for the human cytological developments beginning from gastrulation and endoderm formation.
SOX17 promoter is highly methylated in primary tumors and in corresponding plasma samples both in operable and advanced non-small cell lung cancer.
The definitive endoderm and foregut endoderm differentiation capabilities of Wnt (zeige WNT2 Antikörper) pathway-modulated cells were determined based on the expression levels of the endodermal transcription factors SOX17 and FOXA2 (zeige FOXA2 Antikörper) and those of the transcription activator GATA4 (zeige GATA4 Antikörper) and the alpha-fetoprotein (AFP (zeige AFP Antikörper)) gene, respectively.
Knockdown of OCT4 (zeige POU5F1 Antikörper) during differentiation inhibits mesendoderm formation and removal of the H3K27me3 mark from the SOX17 promoter, suggesting that OCT4 (zeige POU5F1 Antikörper) acts to induce removal of the Polycomb2 complex.
high expression of the Sox17 associated pathway in medium and small arteries indicates that Brain arteriovenous malformation vessels are intrinsically active
Targeted knockdown of Sox17 and Chd (zeige CHRD Antikörper) in dorsal forerunner cells led to aberrant Left-Right (L-R) asymmetry establishment, as visualized by the expression of southpaw and lefty (zeige LEFTY2 Antikörper), and heart and pancreas placement in the embryo.
knockout of dusp4 (zeige DUSP4 Antikörper) revealed a specific loss of sox17, establishing a new class of endoderm specification defect
Results describe sox17 cis (zeige CISH Antikörper)-regulatory elements, and examine the specific input predictions of the gene regulatory networks.
The defective gallbladder contraction positively correlated with the severity of embryonic hepatitis in Sox17(+/-) embryos, suggesting a potential contribution of embryonic cholecystitis and fetal gallbladder contraction in the early pathogenesis of congenital biliary atresia.
Sox17 disruption in epithelial and stromal compartments led to inhibition of endometrial adenogenesis and a loss of reproductive capacity. Epithelium-specific Sox17 disruption resulted in normal adenogenesis although reproductive capacity remained impaired. Non-epithelial, Sox17-positive cells are necessary for adenogenesis and endometrial glands require Sox17 to properly function.
SOX-17 transcription factor is indispensable in developmental angiogenesis and as a positive feedback regulator of VEGF (zeige VEGFA Antikörper) signaling.
findings indicate the role of Sry (zeige SRY Antikörper)-related HMG (zeige SSRP1 Antikörper) box gene-17 (Sox17) in uterine receptivity to embryo implantation.
combined deletion of Sox7 (zeige SOX7 Antikörper), Sox17, and Sox18 (zeige SOX18 Antikörper) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 allele largely restores arterial identity
Sox17 inhibition of Runx1 (zeige RUNX1 Antikörper) and Gata2 (zeige GATA2 Antikörper) maintains endothelial fate in endothelial-to-haematopoietic transition
Sox17 deficiency in mouse can induce intracranial aneurysm under hypertensive conditions, suggesting Sox17 deficiency as a potential genetic factor for IA formation.
These results identify a novel role for Sox17 in adult liver as a modulator of the metabolic adaptation to fasting.
the transcription factor SOX17, which is activated in prospective definitive endoderm cells before intercalation, is necessary for gut (zeige GUSB Antikörper) endoderm morphogenesis and the assembly of the basement membrane that separates gut (zeige GUSB Antikörper) endoderm from mesoderm.
Hhex (zeige HHEX Antikörper) and Cer1 (zeige CER1 Antikörper) are indispensable components of the Sox17 pathway for cardiopoiesis.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
SRY-related HMG-box transcription factor SOX17
, transcription factor SOX-17
, SRY-box 17
, SRY-box containing gene 17
, HMG box transcription factor Sox17-alpha
, sox17 alpha
, transcription factor Sox-17-alpha
, HMG transcription factor SOX17
, SRY (sex determining region Y)-box 17
, SRY (sex determining region Y)-box 17 beta, gene 2
, Transcription factor Sox-17-beta.2
, SRY (sex determining region Y)-box 17-beta.2
, sox7/17 protein
, LOW QUALITY PROTEIN: transcription factor SOX-17