anti-SRY (Sex Determining Region Y)-Box 17 (SOX17) Antikörper

SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Zusätzlich bieten wir Ihnen SOX17 Proteine (4) und SOX17 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SOX17 64321 Q9H6I2
SOX17 312936  
SOX17 20671 Q61473
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Top anti-SOX17 Antikörper auf antikoerper-online.de

Showing 10 out of 91 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-SOX17 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SOX17 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of SOX17 expression in HeLa (A), LNCaP (B), DU145 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert BI, IF, ICS, WB Western blot analysis of Sox17 in definitive endoderm derived from human embryonic stem (ES) cells. H9 human ES cells (WiCell, Madison, WI) were differentiated to definitive endoderm for 3 days (D’Amour et al, 2005) in RPMI medium supplemented with 0.5% FBS, 1× L-glutamine, and 100 ng/ml Activin A (R&D Systems). Lysates from control ES cells (lane 1) and from day 1 (lane 2) and day 3 (lane 3) differentiated cells were probed with Purified Mouse anti-Human Sox17 antibody at 1.0 µg/ml. The presence of Sox17 is demonstrated by the 45-kDa band in human ES-derived definitive endodermal cells (Lane 3), which is absent in H9 human ES cells (Lane 1) and at day 1 of differentiation (Lane 2). Purified Mouse anti-Hsp90 monoclonal antibody (ABIN967957) was used as a gel-loading control (MW 90 kDa). Flow cytometric analysis of Sox17 in definitive endoderm derived from human embryonic stem (ES) cells. H9 human ES cells (WiCell, Madison, WI) grown on an irradiated mouse embryonic feeder layer were differentiated to definitive endoderm for 3 days (D’Amour et al, 2005) in RPMI medium supplemented with 0.5% FBS, 1× L-glutamine, and 100 ng/ml Activin A (R&D Systems). Day-3 differentiated cells were fixed with BD Cytofix buffer and permeabilized with BD™ Phosflow Perm buffer III. The cells were stained with either Purified Mouse IgG1, kappa isotype control (dashed line) or Purified Mouse Anti-human Sox17 antibody (solid line) at matched concentrations. The second-step reagent was APC goat anti-mouse Ig. The histograms were derived from gated events based on light scattering characteristics of the H9-derived endoderm cells. Flow cytometry was performed on a BD LSR™ II flow cytometry system. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$243.52
Details
Human Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Hund Maus Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Ziege APC FACS Detection of SOX17 in Definitive Endoderm-differentiated BG01V Human Stem Cells by Flow Cytometry. Definitive endoderm-differentiated. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$357.65
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB Western Blot: SOX17 Antibody [NBP2-24568] - Analysis of SOX17 in mouse embryo brain lysate in the 1) absence and 2) presence of immunizing peptide using SOX17 antibody at 1 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test. Immunohistochemistry-Paraffin: SOX17 Antibody [NBP2-24568] - Formalin-fixed, paraffin-embedded human uterus (top) and testis (bottom) stained with SOX17 antibody at 10 ug/ml. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Hund Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Hund Kaninchen Unkonjugiert IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with SOX17 antibody ABIN462221 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with SOX17 antibody ABIN462221 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details

SOX17 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Am meisten referenzierte anti-SOX17 Antikörper

  1. Human Monoclonal SOX17 Primary Antibody für BI, IF - ABIN967681 : DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: Efficient differentiation of human embryonic stem cells to definitive endoderm. in Nature biotechnology 2005 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal SOX17 Primary Antibody für FACS - ABIN4895920 : Bernardo, Faial, Gardner, Niakan, Ortmann, Senner, Callery, Trotter, Hemberger, Smith, Bardwell, Moffett, Pedersen: BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. in Cell stem cell 2011 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal SOX17 Primary Antibody für ICC, IF - ABIN4355356 : Schröter, Sleegers, Van Cauwenberghe, Bohndorf, Wruck, Van Broeckhoven, Adjaye: Lymphoblast-derived integration-free iPSC lines from a female and male Alzheimer's disease patient expressing different copy numbers of a coding CNV in the Alzheimer risk gene CR1. in Stem cell research 2016 (PubMed)
    Show all 2 Pubmed References

  4. Dog (Canine) Monoclonal SOX17 Primary Antibody für IF, IHC - ABIN2452377 : Bode, Barghorn, Fritzsche, Riener, Kristiansen, Knuth, Moch: MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 (PubMed)
    Show all 2 Pubmed References

  5. Dog (Canine) Polyclonal SOX17 Primary Antibody für IHC, WB - ABIN2781184 : Zhang, Glöckner, Guo, Machida, Wang, Easwaran, Van Neste, Herman, Schuebel, Watkins, Ahuja, Baylin: Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. in Cancer research 2008 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal SOX17 Primary Antibody für ELISA - ABIN451622 : Kim, Saunders, Morrison: Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. in Cell 2007 (PubMed)

  7. Human Monoclonal SOX17 Primary Antibody für FACS, IF - ABIN2452673 : Takeuchi, Nakatsuji, Suemori: Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. in Scientific reports 2014 (PubMed)

Weitere Antikörper gegen SOX17 Interaktionspartner

Human SRY (Sex Determining Region Y)-Box 17 (SOX17) Interaktionspartner

  1. The combination of methylated SOX17 with cytology better predicted neoplastic grade than cytology alone

  2. SOX17 acts as a tumor suppressor in cholangiocarcinoma and its genetic, molecular and/or pharmacological restoration may represent a new promising therapeutic strategy.

  3. Our results suggest that decreasing SOX17 levels may promote EC development and progression, and that by downregulating MAML3 (zeige MAML3 Antikörper) expression and Wnt (zeige WNT2 Antikörper) signaling, SOX17 acts as a tumor suppressor that may improve outcome in patients with EC.

  4. SOX2 (zeige SOX2 Antikörper) repression in TCam-2 cells can be abrogated by recruitment of the constitutively expressed H3K27 demethylase (zeige MBD2 Antikörper) UTX (zeige KDM6A Antikörper) to the SOX2 (zeige SOX2 Antikörper) promoter through retinoid signaling, leading to expression of neuronal and other lineage genes. SOX17 has been shown to initiate human PGC (zeige PGC Antikörper) specification, with its target PRDM1 (zeige PRDM1 Antikörper) suppressing mesendodermal genes

  5. Dedifferentiation of fibroblasts to CD34 (zeige CD34 Antikörper)(+) progenitor cells gives rise to endothelial cells and erythroblasts in a SOX17-dependent manner.

  6. Study extracted and analyzed the experimentally validated 3D models of SOX17-HMG (zeige SSRP1 Antikörper) domain and beta-catenin (zeige CTNNB1 Antikörper); the molecular level disturbance in the two essential human proteins upon M76A and G103R mutation of SOX17, which further hampers the cell signaling phenomena for the human cytological developments beginning from gastrulation and endoderm formation.

  7. SOX17 promoter is highly methylated in primary tumors and in corresponding plasma samples both in operable and advanced non-small cell lung cancer.

  8. The definitive endoderm and foregut endoderm differentiation capabilities of Wnt (zeige WNT2 Antikörper) pathway-modulated cells were determined based on the expression levels of the endodermal transcription factors SOX17 and FOXA2 (zeige FOXA2 Antikörper) and those of the transcription activator GATA4 (zeige GATA4 Antikörper) and the alpha-fetoprotein (AFP (zeige AFP Antikörper)) gene, respectively.

  9. Knockdown of OCT4 (zeige POU5F1 Antikörper) during differentiation inhibits mesendoderm formation and removal of the H3K27me3 mark from the SOX17 promoter, suggesting that OCT4 (zeige POU5F1 Antikörper) acts to induce removal of the Polycomb2 complex.

  10. high expression of the Sox17 associated pathway in medium and small arteries indicates that Brain arteriovenous malformation vessels are intrinsically active

Zebrafish SRY (Sex Determining Region Y)-Box 17 (SOX17) Interaktionspartner

  1. Targeted knockdown of Sox17 and Chd (zeige CHRD Antikörper) in dorsal forerunner cells led to aberrant Left-Right (L-R) asymmetry establishment, as visualized by the expression of southpaw and lefty (zeige LEFTY2 Antikörper), and heart and pancreas placement in the embryo.

  2. knockout of dusp4 (zeige DUSP4 Antikörper) revealed a specific loss of sox17, establishing a new class of endoderm specification defect

  3. Results describe sox17 cis (zeige CISH Antikörper)-regulatory elements, and examine the specific input predictions of the gene regulatory networks.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 17 (SOX17) Interaktionspartner

  1. The defective gallbladder contraction positively correlated with the severity of embryonic hepatitis in Sox17(+/-) embryos, suggesting a potential contribution of embryonic cholecystitis and fetal gallbladder contraction in the early pathogenesis of congenital biliary atresia.

  2. Sox17 disruption in epithelial and stromal compartments led to inhibition of endometrial adenogenesis and a loss of reproductive capacity. Epithelium-specific Sox17 disruption resulted in normal adenogenesis although reproductive capacity remained impaired. Non-epithelial, Sox17-positive cells are necessary for adenogenesis and endometrial glands require Sox17 to properly function.

  3. SOX-17 transcription factor is indispensable in developmental angiogenesis and as a positive feedback regulator of VEGF (zeige VEGFA Antikörper) signaling.

  4. findings indicate the role of Sry (zeige SRY Antikörper)-related HMG (zeige SSRP1 Antikörper) box gene-17 (Sox17) in uterine receptivity to embryo implantation.

  5. combined deletion of Sox7 (zeige SOX7 Antikörper), Sox17, and Sox18 (zeige SOX18 Antikörper) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 allele largely restores arterial identity

  6. Sox17 inhibition of Runx1 (zeige RUNX1 Antikörper) and Gata2 (zeige GATA2 Antikörper) maintains endothelial fate in endothelial-to-haematopoietic transition

  7. Sox17 deficiency in mouse can induce intracranial aneurysm under hypertensive conditions, suggesting Sox17 deficiency as a potential genetic factor for IA formation.

  8. These results identify a novel role for Sox17 in adult liver as a modulator of the metabolic adaptation to fasting.

  9. the transcription factor SOX17, which is activated in prospective definitive endoderm cells before intercalation, is necessary for gut (zeige GUSB Antikörper) endoderm morphogenesis and the assembly of the basement membrane that separates gut (zeige GUSB Antikörper) endoderm from mesoderm.

  10. Hhex (zeige HHEX Antikörper) and Cer1 (zeige CER1 Antikörper) are indispensable components of the Sox17 pathway for cardiopoiesis.

SOX17 Antigen-Profil

Protein Überblick

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Genbezeichner und Symbole assoziert mit SOX17

  • SRY-box 17 (SOX17) Antikörper
  • SRY (sex determining region Y)-box 17 (sox17) Antikörper
  • SRY box 17 (Sox17) Antikörper
  • SRY-box 17 alpha (sox17a) Antikörper
  • SRY (sex determining region Y)-box 17 beta, gene 2 (sox17b.2) Antikörper
  • SRY-box 17 (sox17) Antikörper
  • sox7/17 protein (sox7/17) Antikörper
  • SRY (sex determining region Y)-box 17 (Sox17) Antikörper
  • SRY-box 17 (Sox17) Antikörper
  • Sox Antikörper
  • sox7/17 Antikörper
  • sox17 Antikörper
  • sox17-alpha Antikörper
  • Sox17alpha Antikörper
  • tSox17alpha Antikörper
  • tSox17beta Antikörper
  • VUR3 Antikörper
  • Xsox17 Antikörper
  • Xsox17-alpha Antikörper
  • xsox17a Antikörper
  • Xsox17alpha Antikörper
  • xSox17alpha1 Antikörper
  • xSox17alpha2 Antikörper

Bezeichner auf Proteinebene für SOX17

SRY-related HMG-box transcription factor SOX17 , transcription factor SOX-17 , SRY-box 17 , SRY-box containing gene 17 , HMG box transcription factor Sox17-alpha , sox17 alpha , transcription factor Sox-17-alpha , HMG transcription factor SOX17 , SRY (sex determining region Y)-box 17 , SRY (sex determining region Y)-box 17 beta, gene 2 , Transcription factor Sox-17-beta.2 , SRY (sex determining region Y)-box 17-beta.2 , sox7/17 protein , LOW QUALITY PROTEIN: transcription factor SOX-17

GENE ID SPEZIES
64321 Homo sapiens
30544 Danio rerio
312936 Rattus norvegicus
395066 Xenopus (Silurana) tropicalis
428534 Gallus gallus
486955 Canis lupus familiaris
534010 Bos taurus
694097 Macaca mulatta
740572 Pan troglodytes
100038235 Xenopus (Silurana) tropicalis
100304455 Oryzias latipes
100591356 Nomascus leucogenys
100303486 Saccoglossus kowalevskii
20671 Mus musculus
100719584 Cavia porcellus
100154087 Sus scrofa
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