SOX17 Antikörper (C-Term)

Produktnummer ABIN3032723

Produktdetails anti-SOX17 Antikörper

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Sox17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Andere Bezeichnung: Sox17 (SOX17 Produkte)

Synonyme: VUR3 antikoerper, SOX17 antikoerper, Sox17alpha antikoerper, Xsox17 antikoerper, Xsox17-alpha antikoerper, Xsox17alpha antikoerper, sox17-alpha antikoerper, tSox17alpha antikoerper, xSox17alpha1 antikoerper, xSox17alpha2 antikoerper, xsox17a antikoerper, sox17 antikoerper, sox7/17 antikoerper, Sox antikoerper, SRY-box 17 antikoerper, SRY (sex determining region Y)-box 17 antikoerper, SRY box 17 antikoerper, SRY-box 17 alpha antikoerper, sox7/17 protein antikoerper, SOX17 antikoerper, sox17 antikoerper, Sox17 antikoerper, sox17a antikoerper, sox7/17 antikoerper

Hintergrund: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

UniProt: Q61473