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Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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High SPANXC expression is associated with breast cancer invasion.
study reports the isolation of AKAP3 (zeige AKAP3 Antikörper) and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera
SPANXC was found in ejaculated spermatozoa and spermatids.
genetic variability of SPANX-B (zeige SPANXB1 Antikörper) & SPANX-C in a sample of Sicilian male population including patients with cutaneous melanoma; statistical significant difference for a particular class of SPANX-C gene was found comparing patients with melanoma & controls
SPANX-C gene dosage analysis in Down's syndrome subjects with undescended testes
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
, cancer-testis-associated protein CTp11
, cancer/testis antigen 11.3
, cancer/testis antigen family 11, member 3
, cancer/testis-associated protein CTp11
, cancer/testis-associated protein of 11 kD
, nuclear-associated protein SPAN-Xc
, sperm protein associated with the nucleus on the X chromosome C
, sperm protein associated with the nucleus, X chromosome, family member C