SLIT and NTRK-Like Family, Member 1 Proteine (SLITRK1)

This intronless gene encodes a member of the SLITRK protein family. Zusätzlich bieten wir Ihnen SLIT and NTRK-Like Family, Member 1 Antikörper (73) und SLIT and NTRK-Like Family, Member 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLITRK1 114798 Q96PX8
SLITRK1 76965 Q810C1
Ratte SLITRK1 SLITRK1 306147  
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Top SLIT and NTRK-Like Family, Member 1 Proteine auf antikoerper-online.de

Showing 3 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$7,639.51
Details
Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details

SLITRK1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,

Weitere Proteine zu SLIT and NTRK-Like Family, Member 1 (SLITRK1) Interaktionspartnern

Human SLIT and NTRK-Like Family, Member 1 (SLITRK1) Interaktionspartner

  1. Data provide partial support for the implication of SLITRK1 in the pathogenesis of Tourette syndrome.

  2. the N400I variant of SLITRK1 may have a role in obsessive-compulsive disorder

  3. The study of chromosomal aberrations in Tourette syndrome etiology has implicated multiple genes, with SLITRK1 being the most prominent example.

  4. One of the few genes that has been linked to TS is the SLITRK1 (Slit and Trk (zeige NTRK1 Proteine)-like 1) gene, where four variations have been suggested as possible disease-associated changes

  5. DM1 motoneuron/muscle cell cocultures showed alterations that are consistent with the known role of SLITRK genes in neurite outgrowth, neuritogenesis, and synaptogenesis; functional defects can be directly attributed to SLITRK misexpression.

  6. The study of this study support that SLITRK1 var321 is association to Tourette syndrome.

  7. findings support the association of rare SLITRK1 sequence variants with Tourette's syndrome

  8. SLITRK1 trouble in Tourette's syndrome.

  9. Rare variations in SLITRK1 result in disorders of the obsessive-complusive disease spectrum

  10. negative results of the SLITRK1 analysis point to genetic heterogeneity in Tourette syndrome

Mouse (Murine) SLIT and NTRK-Like Family, Member 1 (SLITRK1) Interaktionspartner

  1. These results lead us to conclude that noradrenergic mechanisms are involved in the behavioral abnormalities of Slitrk1-deficient mice. Elevated anxiety due to Slitrk1 dysfunction may contribute to the pathogenesis of neuropsychiatric diseases

  2. Data show that the expression of SLITRK1 is dynamic and specifically associated with the circuits most commonly implicated in TS and related disorders, suggesting that SLITRK1 contributes to the development of corticostriatal-thalamocortical circuits.

SLIT and NTRK-Like Family, Member 1 (SLITRK1) Protein Überblick

Protein Überblick

This intronless gene encodes a member of the SLITRK protein family. These proteins are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. The protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome.

Genbezeichner und Symbole assoziert mit SLITRK1

  • SLIT and NTRK like family member 1 (SLITRK1)
  • SLIT and NTRK like family member 1 (slitrk1)
  • SLIT and NTRK-like family, member 1 (Slitrk1)
  • 3200001I04Rik Protein
  • DKFZp459G0529 Protein
  • LRRC12 Protein
  • TTM Protein

Bezeichner auf Proteinebene für SLITRK1

SLIT and NTRK-like protein 1 , SLIT and NTRK-like family, member 1 , slit and trk like 1 protein , leucine-rich repeat-containing protein 12 , slit and trk like gene 1

GENE ID SPEZIES
100050220 Equus caballus
467291 Pan troglodytes
100172686 Pongo abelii
699217 Macaca mulatta
100124997 Xenopus (Silurana) tropicalis
100347903 Oryctolagus cuniculus
100589121 Nomascus leucogenys
114798 Homo sapiens
485509 Canis lupus familiaris
100152470 Sus scrofa
615880 Bos taurus
76965 Mus musculus
306147 Rattus norvegicus
418798 Gallus gallus
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