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SH3D19 encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. Zusätzlich bieten wir Ihnen SH3D19 Antikörper (20) und und viele weitere Produktgruppen zu diesem Protein an.
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identified and characterized EBP, a novel EEN binding protein that interacts with the SH3 domain of EEN; normally expressed in cytoplasm but recruited to the nucleus by MLL-EEN [EBP]
yeast two-hybrid screening using the cytoplasmic domain of ADAM12 as bait identified a protein designated Eve-1. Eve-1 plays a role in positively regulating the activity of ADAMs in the signaling of EGFR-ligand shedding.
occurrence of an unusual TG 3' splice site in intron 6
Sh3d19 transcripts in mouse skin expressed in accordance with hair cycle. Transcripts detected predominantly in medulla cells at level corresponding to keratogenous zone of hair follicles during mid and late anagen phases.
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
SH3 domain protein D19
, SH3 domain-containing protein 19
, SH3 domain containing 19
, ADAM-binding protein Eve-1
, EEN-binding protein
, SH3 domain containing protein D 19