SET Domain Containing (Lysine Methyltransferase) 8 Proteine
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
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11 Treffer
custom-made
SETD8
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SETD8
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SETD8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
SETD8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS
SETD8
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 85% by SDS-PAGE
SDS
custom-made
SETD8
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
SETD8
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Rockland 009-001-t28s
SETD8
Spezies: Human
Wirt: Insect cells (Sf9)
Recombinant
>85%
WB
Rockland Original
SETD8
Spezies: Xenopus tropicalis
Wirt: Hefe
Recombinant
> 90 %
ELISA
SETD8
Spezies: Schizosaccharomyces pombe
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aliase für SET Domain Containing (Lysine Methyltransferase) 8 Proteine
lysine methyltransferase 5A (KMT5A) Proteinelysine methyltransferase 5A (Kmt5a) Proteine
lysine methyltransferase 5Ab (kmt5ab) Proteine
lysine methyltransferase 5A S homeolog (kmt5a.S) Proteine
lysine methyltransferase 5Aa (kmt5aa) Proteine
2410195B05Rik Proteine
AA617402 Proteine
AW536475 Proteine
KMT5A Proteine
kmt5a Proteine
kmt5a-a Proteine
PR-Set7 Proteine
PR-SET7 Proteine
Pr-set7 Proteine
RGD1305893 Proteine
SET07 Proteine
SET8 Proteine
set8a Proteine
Setd8 Proteine
setd8 Proteine
setd8-a Proteine
setd8a Proteine
setd8b Proteine
wu:fc23f12 Proteine
wu:fj33f02 Proteine
zgc:153719 Proteine
zgc:171649 Proteine
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