SET Domain Containing (Lysine Methyltransferase) 7 Proteine (SETD7)

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. Zusätzlich bieten wir Ihnen SETD7 Antikörper (113) und SETD7 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SETD7 80854 Q8WTS6
SETD7 73251 Q8VHL1
Ratte SETD7 SETD7 689954  
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Top SETD7 Proteine auf antikoerper-online.de

Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$437.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
$814.00
Details
Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,001.17
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$261.54
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$400.46
Details
Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 1 bis 2 Tage
$460.83
Details

SETD7 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine)

Weitere Proteine zu SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Interaktionspartnern

Human SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Interaktionspartner

  1. Methylation at K436 and K595 respectively by Set7 increases the stability and DNA binding ability of Gli3 (zeige GLI3 Proteine), resulting in an enhancement of Shh (zeige SHH Proteine) signaling activation.

  2. the methyltransferase Set9 potentiates TGF-beta (zeige TGFB1 Proteine) signaling by targeting Smad7 (zeige SMAD7 Proteine), an inhibitory downstream effector.

  3. SETD7 plays a critical role in HCC (zeige FAM126A Proteine), and its immunohistochemistry signature provides potential clinical significance for personalized prediction of HCC (zeige FAM126A Proteine) prognosis.

  4. These findings underscore the role of KMT7 as an important monomethyltransferase regulating HIV transcription through Tat (zeige TAT Proteine).

  5. High SET7 expression is associated with breast cancer.

  6. SET7 was required for GATA1 (zeige GATA1 Proteine)-induced breast tumor angiogenesis and growth in nude mice. GATA1 (zeige GATA1 Proteine) and SET7 are independent poor prognostic factors in breast cancer.

  7. SET7/SET9-mediated YY1 (zeige YY1 Proteine) methylation was shown to be involved in YY1 (zeige YY1 Proteine)-regulated gene transcription and cell proliferation.

  8. These results demonstrate that S...O chalcogen bonds contribute to AdoMet (zeige MAT1A Proteine) recognition and can enable methyltransferases to distinguish between substrate and product.

  9. Reduced expression of SET7 is associated with gastric cancer progression.

  10. study identified a novel locus associated with serum lycopene concentrations and results raise a number of possibilities regarding the nature of the relationship between SETD7 and lycopene, both independently associated with prostate cancer.

Mouse (Murine) SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Interaktionspartner

  1. the methyltransferase Set9 potentiates TGF-beta (zeige TGFB1 Proteine) signaling by targeting Smad7 (zeige SMAD7 Proteine), an inhibitory downstream effector.

  2. SETD7 plays an important role in intestinal epithelial cell (IEC) biology during infection.

  3. We observe Set7-mediated modification of serum response factor (SRF) and mono-methylation of histone H4 lysine 4 (H3K4me1) regulate gene expression. We conclude the broad substrate specificity of Set7 serves to control key transcriptional networks in embryonic stem cells.

  4. SETD7 is required for Wnt (zeige WNT2 Proteine)-driven intestinal tumorigenesis and regeneration. SETD7-dependent methylation of YAP (zeige YAP1 Proteine) facilitates Wnt (zeige WNT2 Proteine)-induced nuclear accumulation of beta-catenin (zeige CTNNB1 Proteine).

  5. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  6. Data indicate that the ability of transcription factor Pdx1 (zeige PDX1 Proteine) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  7. study found that Set7 is a modifier of the Hippo pathway. Mice that lack Set7 have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  8. The response to hyperglycemia in vascular endothelial cells involves Set7 mediated changes in chromatin remodeling and gene expression.

  9. Set7/9-mediated methylation of p53 (zeige TP53 Proteine) does not represent a major regulatory event and does not appreciably control p53 (zeige TP53 Proteine) activity in vivo.

  10. Set7/9 is dispensable for p53 (zeige TP53 Proteine) function in the mouse.

SETD7 Protein Überblick

Protein Überblick

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Genbezeichner und Symbole assoziert mit SETD7

  • SET domain containing lysine methyltransferase 7 (SETD7)
  • SET domain containing (lysine methyltransferase) 7 (setd7)
  • SET domain containing (lysine methyltransferase) 7 (Setd7)
  • 1600028F23Rik Protein
  • H3K4MT Protein
  • KMT7 Protein
  • mKIAA1717 Protein
  • Set7 Protein
  • Set7/9 Protein
  • SET9 Protein
  • zgc:92330 Protein
  • zgc:101860 Protein

Bezeichner auf Proteinebene für SETD7

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

GENE ID SPEZIES
80854 Homo sapiens
436729 Danio rerio
73251 Mus musculus
689954 Rattus norvegicus
476079 Canis lupus familiaris
Ausgewählte Anbieter für SETD7 Proteine (SETD7)
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