SEC14-Like 2 (S. Cerevisiae) Proteine (SEC14L2)

SEC14L2 encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. Zusätzlich bieten wir Ihnen SEC14-Like 2 (S. Cerevisiae) Antikörper (57) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SEC14L2 23541 O76054
SEC14L2 67815 Q99J08
SEC14L2 116486  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,116.67
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,116.67
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SEC14L2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu SEC14-Like 2 (S. Cerevisiae) (SEC14L2) Interaktionspartnern

Human SEC14-Like 2 (S. Cerevisiae) (SEC14L2) Interaktionspartner

  1. Here, the authors report that the zebrafish/human phosphatidylinositol transfer protein Sec14l3/SEC14L2 act as GTPase proteins to transduce Wnt signals from Frizzled to phospholipase C (PLC).

  2. hTAP1 reduces the in vitro activity of the phosphatidylinositol-3-kinase gamma (PI3Kgamma) indicating the formation of a stalled/inactive hTAP1/PI3Kgamma heterodimer.

  3. PI3Kgamma-induced VEGF expression was reduced when the human tocopherol-associated protein 1 (hTAP1/SEC14L2) was overexpressed suggesting formation of an inactive PI3Kgamma/hTAP1 heterodimer.

  4. SEC14L2 enabled RNA replication of diverse HCV genotypes in several human hepatoma cell lines

  5. novel association between the rs737723 polymorphism (SEC14L2/TAP) and higher primary open-angle glaucoma risk

  6. TAP expression was significantly correlated with Her2/neu receptor expression and breast cancer stage.

  7. Discusses cloning of rat SEC14-like protein 3 and mentions three human SPF-related genes, known as SEC14-like protein 1, 2 and 3.

  8. SPF has two domain topology, and the ligand binding cavity has a peculiar horseshoe-like shape

  9. phosphorylation enhances its ability to stimulate microsomal squalene monooxygenase; phosphorylation may provide a means for the rapid short term modulation of cholesterol synthesis

  10. Data report the three-dimensional crystal structure of human supernatant protein factor in complex with RRR-alpha-tocopherylquinone, the major physiological oxidation product of RRR-alpha-tocopherol, at a resolution of 1.95A.

  11. TAP not only mediates vitamin E absorption to facilitate vitamin E antiproliferation effect in prostate cancer cells, but also functions like a tumor suppressor gene to control cancer cell viability through a non-vitamin E manner.

  12. reduced expression of TAP was associated with the cell proliferation status of prostate cancer, adverse pathological parameters and the increased risk of recurrence

  13. Genetic variation in TTPA and SEC14L2 is associated with serum alpha-tocopherol but does not have a direct effect on prostate cancer when vitamin E is administered.

  14. These findings are consistent with alpha-tocopherol-associated protein acting as an antiproliferative factor in estrogen-receptor-positive luminal cells in normal/benign breast tissue

  15. Fndings raise the possibility that TAP/Sec14L2 may serve as a tumor suppressor in breast carcinogenesis.

SEC14-Like 2 (S. Cerevisiae) (SEC14L2) Protein Überblick

Protein Überblick

This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit SEC14L2

  • SEC14 like lipid binding 2 (SEC14L2)
  • SEC14-like lipid binding 2 (Sec14l2)
  • 1300013M05Rik Protein
  • C22orf6 Protein
  • SEC14L2 Protein
  • Spf Protein
  • TAP Protein
  • TAP1 Protein

Bezeichner auf Proteinebene für SEC14L2

SEC14-like protein 2 , alpha-tocopherol-associated protein , squalene transfer protein , supernatant protein factor , tocopherol-associated protein , TAP , bTAP , SEC14-like 2

GENE ID SPEZIES
23541 Homo sapiens
477539 Canis lupus familiaris
100152451 Sus scrofa
282469 Bos taurus
67815 Mus musculus
116486 Rattus norvegicus
417008 Gallus gallus
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