anti-Runt-Related Transcription Factor 1 (RUNX1) Antikörper

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. Zusätzlich bieten wir Ihnen RUNX1 Kits (10) und RUNX1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RUNX1 12394 Q03347
RUNX1 861 Q01196
RUNX1 50662 Q63046
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Top anti-RUNX1 Antikörper auf antikoerper-online.de

Showing 10 out of 289 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB AML-1/Runx1 antibody tested by Western blot. Detection of AML-1/Runx1 by Western blot analysis. Positive detection of AML-1/Runx1 in nuclear extracts derived from Jurkat cells at 1:500 (lane 1) and 1:1,000 (lane 2) dilutions. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-RUNX1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500 <br /> Positive Control: Jurkat cell lysate <br /> RUNX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-RUNX1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Jurkat cell lysate <br /> RUNX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Sample Type : Mouse, post-natal day (p) 0 retinal ganglion cells Primary Antibody Dilution : 1:1500 Secondary Antibody : Donkey anti rabbit IgG Alexa 594 Secondary Antibody Dilution : 1:1000 Gene Name : RUNX1 Submitted by : Anonymous WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: PANC1 cell lysate There is BioGPS gene expression data showing that RUNX1 is expressed in PANC1 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>PANC1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-RUNX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>SH-SYSY cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-RUNX1/AML1 Picoband antibody , All lanes: Anti RUNX1 at 0.5ug/ml WB: Recombinant Human RUNX1 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD Anti-RUNX1/AML1 Picoband antibody , IHC(P): Mouse Intestine Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Huhn Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of RUNX1 staining in THP1 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of RUNX1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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RUNX1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-RUNX1 Antikörper

  1. Human Polyclonal RUNX1 Primary Antibody für WB - ABIN2668716 : Zaidi, Dowdy, van Wijnen, Lian, Raza, Stein, Croce, Stein: Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. in Cancer research 2009 (PubMed)
    Show all 19 Pubmed References

  2. Human Monoclonal RUNX1 Primary Antibody für ELISA, WB - ABIN969390 : Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. in Journal of virology 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal RUNX1 Primary Antibody für IF, IHC (p) - ABIN514054 : Hussein, Dralle, Theophile, Kreipe, Bock: Megakaryocytic expression of miRNA 10a, 17-5p, 20a and 126 in Philadelphia chromosome-negative myeloproliferative neoplasm. in Annals of hematology 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal RUNX1 Primary Antibody für WB - ABIN537342 : Srivastava, Srivastava: Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line. in Leukemia research 2005 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal RUNX1 Primary Antibody für ICC, ELISA - ABIN969389 : Zharlyganova, Harada, Harada, Shinkarev, Zhumadilov, Zhunusova, Tchaizhunusova, Apsalikov, Kemaikin, Zhumadilov, Kawano, Kimura, Hoshi: High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semipalatinsk nuclear test site. in Journal of radiation research 2008 (PubMed)

  6. Human Monoclonal RUNX1 Primary Antibody für ELISA, WB - ABIN966980 : Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal RUNX1 Primary Antibody für IF, IHC (p) - ABIN514053 : Keita, Bachvarova, Morin, Plante, Gregoire, Renaud, Sebastianelli, Trinh, Bachvarov: The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion. in Cell cycle (Georgetown, Tex.) 2013 (PubMed)

  8. Human Monoclonal RUNX1 Primary Antibody für IF, IHC (p) - ABIN2476393 : Tsou, Ransom, Gerlt, Powers, Kenyon: Selection and characterization of a mutant of the cloned gene for mandelate racemase that confers resistance to an affinity label by greatly enhanced production of enzyme. in Biochemistry 1989 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal RUNX1 Primary Antibody für WB - ABIN2801939 : Miyoshi, Shimizu, Kozu, Maseki, Kaneko, Ohki: t(8,21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  10. Cow (Bovine) Polyclonal RUNX1 Primary Antibody für IHC, WB - ABIN2777187 : Takeshita, Ichikawa, Nitta, Goyama, Asai, Ogawa, Chiba, Kurokawa: AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1. in Leukemia 2008 (PubMed)

Weitere Antikörper gegen RUNX1 Interaktionspartner

Mouse (Murine) Runt-Related Transcription Factor 1 (RUNX1) Interaktionspartner

  1. the ability of Runx1 to induce endothelial-to-hematopoietic transition (EHT (zeige CBFA2T2 Antikörper)) in non-hemogenic endothelial cells depends on the anatomical location of the cell and the developmental age of the conceptus

  2. CDK6 (zeige CDK6 Antikörper) kinase activity negatively regulates the conversion of fat-storing cells into fat-burning cells by suppressing RUNX1, and may be a therapeutic target for the treatment of obesity and related metabolic diseases

  3. RUNX1 dosage plays a pivotal role in hemogenic endothelium maturation and the establishment of the hematopoietic system.

  4. These results suggest that RUNX1 may be an essential modulator in BMP9 (zeige GDF2 Antikörper)- induced osteogenic differentiation of mesenchymal stem cells.

  5. Loss of Runx1 and Runx2 (zeige RUNX2 Antikörper) inhibits prostate cell motility.

  6. In vivo, in vitro and systems biology results show that Runx1 exerts a pro-neurogenic function in neural precursor cells in vitro, while in vivo data remained inconclusive.

  7. High RUNX1 expression is associated with lymphoma.

  8. Specific Runx1-bound enhancer elements critically modulate lineage-dependent expressions of PLZF (zeige ZBTB16 Antikörper).

  9. Study reveals a previously unrecognized synergism between ETV6 (zeige ETV6 Antikörper)/RUNX1 and BCL2 (zeige BCL2 Antikörper) impacting on malignant disease and autoimmunity.

  10. Data provide evidence that Runx1 plays a role in regulating the sphingolipid rheostat in normal development and that perturbation of this cell fate regulator contributes to Runx-driven lymphomagenesis.

Human Runt-Related Transcription Factor 1 (RUNX1) Interaktionspartner

  1. Altogether, these results revealed an unexpected and important epigenetic mini-circuit of AML1-ETO (zeige RUNX1T1 Antikörper)/THAP10 (zeige THAP10 Antikörper)/miR (zeige MLXIP Antikörper)-383 in t(8;21) acute myeloid leukaemia, in which epigenetic suppression of THAP10 (zeige THAP10 Antikörper) predicts a poor clinical outcome and represents a novel therapeutic target.

  2. Several studies addressed the mechanism by which ETV6 (zeige ETV6 Antikörper)/RUNX1 (E/R) contributes to leukemogenesis, including the necessary secondary genetic lesions, the cellular framework in which E/R initially arises and the maintenance of a pre-leukemic condition. [review]

  3. MLD (zeige ARSA Antikörper)- and MLD (zeige ARSA Antikörper)+ RUNX1-mutated AML differ in some associations to genetic markers, such as +13 or IDH2 (zeige IDH2 Antikörper) mutation status without prognostic impact in multivariate analysis. However, in RUNX1-mutated AML, the overall pattern shows a specific landscape with high incidences of trisomies (such as +8 and +13), and mutations in the spliceosome and in chromatin modifiers

  4. RUNX1-RUNX1T1 (zeige RUNX1T1 Antikörper) transcript levels were measured in bone marrow samples collected from 208 patients at scheduled time points after transplantation.Over 90% of the 175 patients who were in continuous complete remission had a >/=3-log reduction in RUNX1-RUNX1T1 (zeige RUNX1T1 Antikörper) transcript levels from the time of diagnosis at each time point after transplantation and a >/=4-log reduction at >/=12 months.

  5. RUNX1 defects causing haploinsufficiency are thought to be associated with a lower incidence of myeloid malignancies when compared to those patients with dominant-negative RUNX1 defects.

  6. This result suggests that TET2 (zeige TET2 Antikörper)(P1962T) mutation in association with germline RUNX1(R174Q) mutation leads to amplification of a haematopoietic clone susceptible to acquire other transforming alterations

  7. Presence of fusion the genes BCR/ABL1, ETV6/RUNX1, and MLL/AF4 does not have any impact on the clinical and laboratory features of ALL at presentation.

  8. ETV6 (zeige ETV6 Antikörper)/RUNX1 (+) ALL may be heterogeneous in terms of prognosis, and variables such as MRD at end ofremission induction or additional structural abnormalities of 12p could define a subset of patients who are likely to have poor outcome.

  9. High RUNX1 expression is associated with lymphoma.

  10. PLDN (zeige PLDN Antikörper) is a direct target of RUNX1 and its dysregulation is a mechanism for platelet dense granule deficiency associated with RUNX1 haplodeficiency

Zebrafish Runt-Related Transcription Factor 1 (RUNX1) Interaktionspartner

  1. Our data suggest that runx1 and cbfb are required at 2 different steps during early hematopoietic stem cell development

  2. We propose that cohesin and CTCF (zeige CTCF Antikörper) have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  3. Morpholino knockdown of Myef2 (zeige MYEF2 Antikörper) or Runx1 in zebrafish results in reduced numbers of hematopoietic stem cells, suggesting that these two factors also interact in vivo to regulate hematopoiesis.

  4. Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. hematopoietic stem cell numbers depended on activity of the transcription factor Runx1, on blood flow, and on proper development of the dorsal aorta

  6. in zebrafish adult HSCs can be formed without an intact runx1.

  7. Zebrafish embryos lacking Rad21 (zeige RAD21 Antikörper), or cohesin subunit Smc3 (zeige SMC3 Antikörper), fail to express runx3 (zeige RUNX3 Antikörper) and lose hematopoietic runx1 expression in early embryonic development.

Xenopus laevis Runt-Related Transcription Factor 1 (RUNX1) Interaktionspartner

  1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

  2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL).

  3. reveal a shift in Runx2 (zeige RUNX2 Antikörper) function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage

RUNX1 Antigen-Profil

Protein Überblick

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RUNX1

  • uncharacterized LOC473981 (LOC473981) Antikörper
  • runt-related transcription factor (runt) Antikörper
  • runt related transcription factor 1 (Runx1) Antikörper
  • runt related transcription factor 1 (RUNX1) Antikörper
  • runt-related transcription factor 1 (runx1) Antikörper
  • runt related transcription factor 1 L homeolog (runx1.L) Antikörper
  • runt-related transcription factor 1 (RUNX1) Antikörper
  • runt-related transcription factor 1 (Runx1) Antikörper
  • AI462102 Antikörper
  • aml Antikörper
  • aml-1 Antikörper
  • Aml1 Antikörper
  • aml1-evi-1 Antikörper
  • amlcr1 Antikörper
  • cbfa2 Antikörper
  • evi-1 Antikörper
  • Pebp2a2 Antikörper
  • pebp2ab Antikörper
  • Pebpa2b Antikörper
  • Runx-1 Antikörper
  • runx1 Antikörper
  • runxa Antikörper
  • XAML Antikörper
  • Xaml1 Antikörper

Bezeichner auf Proteinebene für RUNX1

runt-related transcription factor 1 , runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) , runt-related transcription factor , runt protein , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core binding factor alpha 2 , core-binding factor subunit alpha-2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit , runt domain, alpha subunit 2 , AML1-EVI-1 fusion protein , core-binding factor, runt domain, alpha subunit 2 , aml1 , runt-related transcription factor a , runx1a , Acute myeloid leukemia 1 protein , Core-binding factor subunit alpha-2 , aml1 oncogene , ch-runtB2 , acute myeloid leukemia 1 , factor, runt domain, alpha subunit 2 , core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene) , runt related transcription factor 1

GENE ID SPEZIES
473981 Pan troglodytes
100302713 Saccoglossus kowalevskii
12394 Mus musculus
861 Homo sapiens
58126 Danio rerio
379657 Xenopus laevis
396152 Gallus gallus
487746 Canis lupus familiaris
529631 Bos taurus
50662 Rattus norvegicus
100512633 Sus scrofa
100724149 Cavia porcellus
Ausgewählte Anbieter für anti-RUNX1 (RUNX1) Antikörper
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