anti-Ring Finger Protein 2 (RNF2) Antikörper

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. Zusätzlich bieten wir Ihnen RNF2 Proteine (7) und RNF2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF2 6045 Q99496
RNF2 19821 Q9CQJ4
RNF2 304850 Q4KLY4
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Top anti-RNF2 Antikörper auf antikoerper-online.de

Showing 10 out of 89 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RNF2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Daudi cell lysate RNF2 is supported by BioGPS gene expression data to be expressed in Daudi WB Suggested Anti-RNF2 antibody Titration: 1 ug/mL Sample Type: Human Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-RNF2 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184925 staining (0.5 µg/ml) of K562 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
Details
Human Maus Unkonjugiert ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Maus Unkonjugiert WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.34 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Maus Unkonjugiert IF, ELISA, WB RNF2 monoclonal antibody (M05), clone 2B6. Western Blot analysis of RNF2 expression in Hela S3 NE . RNF2 monoclonal antibody (M05), clone 2B6. Western Blot analysis of RNF2 expression in human placenta. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
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Human Kaninchen Unkonjugiert ChIP, IF, IHC, IP, WB 100 μL Anmelden zum Anzeigen 16 Days
$366.77
Details
Human Maus Unkonjugiert RNAi, ELISA, WB RNF2 monoclonal antibody (M01), clone 6C2 Western Blot analysis of RNF2 expression in NIH/3T3 . Western blot analysis of RNF2 over-expressed 293 cell line, cotransfected with RNF2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RNF2 monoclonal antibody (M01), clone 6C2. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

Am meisten referenzierte anti-RNF2 Antikörper

  1. Human Monoclonal RNF2 Primary Antibody für ChIPSeq, ChIP - ABIN2668629 : Basu, Wilkinson, Colavita, Fennelly, Atchison: YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. in Nucleic acids research 2014 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF2 Primary Antibody für RNAi, ELISA - ABIN562662 : Ohtsubo, Yasunaga, Ohno, Tsumura, Okada, Ishikawa, Shirao, Kikuchi, Nishitani, Kobayashi, Takihara: Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal RNF2 Primary Antibody für IHC, IHC (p) - ABIN4350772 : Holdt, Hoffmann, Sass, Langenberger, Scholz, Krohn, Finstermeier, Stahringer, Wilfert, Beutner, Gielen, Schuler, Gäbel, Bergert, Bechmann, Stadler, Thiery, Teupser: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. in PLoS genetics 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal RNF2 Primary Antibody für ELISA, WB - ABIN547012 : Tuckfield, Clouston, Wilanowski, Zhao, Cunningham, Jane: Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. in Molecular and cellular biology 2002 (PubMed)

Weitere Antikörper gegen RNF2 Interaktionspartner

Human Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. these data indicate that RING1B and EZH2 repress the innate inflammatory cutaneous squamous cell carcinoma function and impair tumor immunosurveillance

  2. Observations demonstrated that Plk1 directly interacts with RNF2 and degrades RNF2 via the ubiquitindependent degradation pathway. RNF2 may be used as a new target for mitotic regulation and tumorigenesis.

  3. These data suggest that RNF2 is an important upstream negative regulator of SIK1 and that restoration of SIK1 levels induced by loss of RNF2 inhibited HCC cell growth and promoted apoptosis, which may represent a promising therapeutic strategy for HCC treatment.

  4. Study found that prostate cancer (PCa) tissues have high RNF2 expression which is positively correlated with tumor grade indicating that RNF2 may have oncogenic function in PCa.

  5. Our findings identify RING1B as a trait of the cell-of-origin in Ewing sarcoma

  6. Study detected RNF2 expression to be overexpressed in esophageal carcinoma cell lines and was associated with the poor prognosis of esophageal carcinoma patients. Data also reflect its important role in the growth of esophageal carcinoma cells by shRNA silencing of RNF2 expression.

  7. overexpression of RNF2, as examined by immunohistochemical analysis, might serve as a novel prognostic biomarker and potential therapeutic target for urothelial carcinoma of the bladder patients.

  8. Our findings support the notion that epigenetic regulators, such as RNF2, directly and functionally control powerful gene networks that are vital in multiple cancer processes.

  9. O-GlcNAc modifies and regulates an essential epigenetic tool, RING1B, which may contribute to human embryonic stem cells pluripotency maintenance and differentiation.

  10. The enzymatic activity of BMI1 and RING1B were evaluated and compared.

  11. Bmi1 and possibly RNF2 may be attractive biomarkers of gemcitabine resistance in the context of RRM1 expression.

  12. combinatorial silencing along with Ezh2 depleted epigenetically modified H2- and H3-histones and inhibited pancreatic cancer cell growth in vitro and in vivo (xenograft model)

  13. BAP1 deficiency causes increased expression of FoxK2 target genes in a Ring1B-Bmi1-dependent manner

  14. Authors describe a critical role for the polycomb group protein Ring1b in nonhomologous end-joining (NHEJ)-mediated end-to-end chromosome fusions.

  15. we identify p63 as a target of Ring1B to regulate Fak expression in breast cancer epithelial cells

  16. Ring1B and the SNAG-associated chromatin modifier EZH2 formed distinct protein complexes with Snail and that EZH2 was required for Snail-Ring1A/B recruitment to the target promoter.

  17. The acidic patch functions within the nucleosome as nucleosomes containing a mutated acidic patch exhibit defective H2A/H2AXub by RNF168 and RING1B/BMI1 in vitro

  18. Data indicate that RING finger protein 2 (RNF2) knockdown can increase the sensitivity of U87 cells to X ray radiation.

  19. Expressed the isolated N-terminal region of Ring1B, N-Ring1B, comprising the first 221 residues of the 334-residue-long Ring1B and found that the N-Ring1B is a well-folded, monomeric fragment, with native-like structure which unfolds irreversibly.

  20. BMI-1 and RING1B expression was enhanced with the development of embryos in early pregnancy.

Mouse (Murine) Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. Data show that RNF2 promotes STAT1/STAT2 disassociation from DNA.

  2. the ability of RING1B, a core component of PRC1, to ubiquitinate histone H2A is dispensable for early mouse embryonic development and much of the gene repression activity of PRC1

  3. RNF2 associates with AMBRA1 to act as an E3 ligase to ubiquitinate AMBRA1 via K48 linkage.

  4. The polycomb component Ring1B regulates the timed termination of Fezf2 expression and thus subcerebral projection neuron production during mouse neocortical development.

  5. Expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a and Cdkn2a, demonstrating that Ring1B simultaneously regulates multiple CDKIs in tissue stem/progenitor cells.

  6. Af9 mediates site-selective physical and functional recruitment of Rnf2 to the alpha-ENaC promoter to constrain basal alpha-ENaC transcription in collecting duct cells.

  7. Ring1b mediates Meis2 promoter and midbrain-specific enhancer association.

  8. Aurora B and Ring1B co-occupy active promoters in resting lymphocytes.

  9. Fbxl10 has a key role in regulating Ring1B recruitment to its target genes and H2AK119 ubiquitylation in embryonic stem cells.

  10. identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 and Rnf2, two central components of the Polycomb repressive complex 1 (PRC1)

  11. Ring1b inactivation in differentiated islet beta cells (Ring1b(betaKO)) did not cause derepression, even after multiple rounds of cell division, suggesting a role for Ring1b in the establishment but not the maintenance of repression

  12. loss of Ring1a/b postnatally results in defective cervical loops and disturbances of enamel and dentin formation in continuously growing incisors

  13. It was shown that Ring1B interacted with multiple complexes in embryonic stem cells. Although H2A.Z co-localized with Eed, Ring1B and CpG islands in chromatin, H2A.Z still blanketed polycomb target loci in the absence of Suz12, Eed, or Ring1B.

  14. Data provide a valuable basis for future investigations aimed at eukaryotic DING proteins, revealing that these proteins seem ubiquitous in mouse tissue.

  15. Ring1B and Suv39h1 have mutually exclusive roles in regulating distinct chromatin states at key developmental genes, and play a part in how lineage specification can be reinforced during early development

  16. Ring1B-mediated chromatin compaction acts to directly limit transcription in embryonic stem cells.

  17. polycomb protein Ring1B regulation by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome

  18. Involved in the specification of the anterior-posterior axis in mice

  19. Rnf2 has a role in mouse gastrulation and cell cycle regulation

  20. Ring1b and ubH2A are involved in the initiation of both imprinted and random X inactivation

Zebrafish Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development.

  2. These results reveal that, in the absence of functional Ring1b, fin bud cells fail to execute the pectoral fin developmental program.

RNF2 Antigen-Profil

Protein Überblick

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Genbezeichner und Symbole assoziert mit RNF2

  • ring finger protein 2 (RNF2) Antikörper
  • ring finger protein 2 (Rnf2) Antikörper
  • ring finger protein 2 (rnf2) Antikörper
  • ring finger protein 2 L homeolog (rnf2.L) Antikörper
  • AI326319 Antikörper
  • AI450156 Antikörper
  • AU019207 Antikörper
  • bap-1 Antikörper
  • bap1 Antikörper
  • ding Antikörper
  • fa19h05 Antikörper
  • hipi3 Antikörper
  • ring1b Antikörper
  • ring2 Antikörper
  • wu:fa19h05 Antikörper
  • wz4556 Antikörper

Bezeichner auf Proteinebene für RNF2

E3 ubiquitin-protein ligase RING2 , HIP2-interacting protein 3 , RING finger protein 1B , RING finger protein BAP-1 , huntingtin-interacting protein 2-interacting protein 3 , protein DinG , RING1b , ring finger protein 1b , wz4566

GENE ID SPEZIES
6045 Homo sapiens
19821 Mus musculus
304850 Rattus norvegicus
327035 Danio rerio
100127274 Xenopus laevis
424452 Gallus gallus
457581 Pan troglodytes
100174504 Pongo abelii
480042 Canis lupus familiaris
540090 Bos taurus
100717673 Cavia porcellus
100344273 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-RNF2 (RNF2) Antikörper
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