Regenerating Islet-Derived 3 alpha Proteine (REG3A)

REG3A encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. Zusätzlich bieten wir Ihnen REG3A Antikörper (120) und REG3A Kits (53) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
REG3A 5068 Q06141
REG3A 19694 O09037
REG3A 171162 P35231
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Top REG3A Proteine auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$492.80
Details
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,326.50
Details
Hefe Syrischer Goldhamster His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,326.50
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details

REG3A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) , ,

Rat (Rattus) , ,
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Am meisten referenzierte REG3A Proteine

  1. Human REG3A Protein expressed in Human Cells - ABIN3216396 : Orelle, Keim, Masciotra, Dagorn, Iovanna: Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. in The Journal of clinical investigation 1993 (PubMed)
    Show all 3 Pubmed References

Weitere Proteine zu Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartnern

Human Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartner

  1. Mice with hepatocytes that express hREG3A, which travels to the intestinal lumen, are less sensitive to colitis than control mice. Suggest reduced oxidative stress preserves the gut (zeige GUSB Proteine) microbiota and its ability to prevent inflammation.

  2. The pancreas reacts to remote lesions and septic insults in mice and rats with increased PSP (zeige MSMB Proteine) synthesis, while PAP is selectively responsive to septic events. Furthermore, our results suggest that serum PSP (zeige MSMB Proteine) in septic patients is predominantly derived through an acute phase response of the pancreas.

  3. Data show that interleukin-2 receptor alpha (zeige IL2RA Proteine), tumor necrosis factor receptor 1 (zeige TNFRSF1A Proteine), serum STimulation-2 (IL1RL1 (zeige IL1RL1 Proteine) gene product), and regenerating islet-derived 3-alpha were significantly associated with non-relapse mortality.

  4. skin injury increases IL-36gamma via the activation of TLR3 (zeige TLR3 Proteine)-SLUG-VDR (zeige CYP27B1 Proteine) axis and IL-36gamma induces REG3A to promote wound healing

  5. Association between a SNP in the REG3A gene, rs7588571, located upstream of the REG3A gene, and bone marrow transplant outcomes including the incidence of chronic GVHD. Since REG (zeige EXTL3 Proteine) proteins control intestinal microbiota, and since intestinal dysbiosis is in part responsible for the development of GVHD, findings lead to the concept that REG3A could have some protective effect through the regulation of gut (zeige GUSB Proteine) microbiota.

  6. Patients with high levels of PAP/REG3A had overall shorter survival as well as poor surgical outcomes with reduced disease-free survival.

  7. Up-regulation of REG3A correlates with colorectal cancer risk.

  8. Regulation network analysis confirmed the cell growth related differentially expressed genes, and further uncovered three transcription factor families with immune functions regulated by REG3A

  9. Reg3A overexpression promoted cell growth in pancreatic cancer. SOCS3 (zeige SOCS3 Proteine) is a key target in cancer by inhibiting cell growth and inducing apoptosis. SOCS3 (zeige SOCS3 Proteine) negatively regulated Reg3A-mediated cell growth in pancreatic cancer.

  10. Serum regenerating islet-derived 3-alpha is a biomarker of mucosal enteropathies

Mouse (Murine) Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartner

  1. skin injury increases IL-36gamma via the activation of TLR3 (zeige TLR3 Proteine)-SLUG-VDR (zeige CYP27B1 Proteine) axis and IL-36gamma induces REG3A to promote wound healing

  2. Data show that regenerating islet-derived 3-alpha (REG3alpha) is a plasma biomarker of gastrointestinal tract graft-versus-host disease that can be combined with clinical stage and histologic grade to improve risk stratification of patients.

  3. Reg2 (zeige FLOT1 Proteine), Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.

  4. Reg3alpha stimulates beta-cell replication, by activating Akt (zeige AKT1 Proteine) kinase and increasing the levels of cyclin D1 (zeige CCND1 Proteine)/CDK4 (zeige CDK4 Proteine).

Golden Syrian Hamster Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartner

  1. data suggest that human adult pancreatic ductal cells retain morphogenetic plasticity and demonstrate that a short exposure to INGAP triggers their differentiation into insulin (zeige INS Proteine)-expressing cells in vitro.

  2. The results indicate that endogenous INGAP plays a "physiological" positive modulatory role in insulin (zeige INS Proteine) secretion, supporting its possible use in the treatment of prediabetes and Type 2 diabetes.

REG3A Protein Überblick

Protein Überblick

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit REG3A

  • regenerating family member 3 alpha (REG3A)
  • regenerating islet-derived 3 alpha (Reg3a)
  • regenerating islet-derived 3 alpha (REG3A)
  • pancreatic beta cell growth factor-like (LOC101829186)
  • AV063448 Protein
  • HIP Protein
  • HIP/PAP Protein
  • INGAP Protein
  • PAP Protein
  • PAP-H Protein
  • PAP1 Protein
  • Pap2 Protein
  • PapII Protein
  • PBCGF Protein
  • PTP Protein
  • REG-III Protein
  • REG3 Protein
  • REG3G Protein

Bezeichner auf Proteinebene für REG3A

PAP homologous protein , REG-3-alpha , hepatocarcinoma-intestine-pancreas , hepatointestinal pancreatic protein , human proislet peptide , pancreatic beta cell growth factor , pancreatitis-associated protein 1 , proliferation-inducing protein 34 , proliferation-inducing protein 42 , reg III-alpha , regenerating islet-derived protein 3-alpha , regenerating islet-derived protein III-alpha , RegIII (alpha) , generating islet-derived, mouse homolog 3 alpha , islet of Langerhans regenerating protein 3 , lithostathine 3 , pancreatitis-associated protein 2 , REG 3 , regIII , regenerating islet-derived protein 3 alpha , ICRF , PSP , REG , islet cells regeneration factor , islet of Langerhans regenerating protein , lithostathine , pancreatic stone protein , pancreatic thread protein , islet neogenesis associated protein , pancreatitis-associated protein , regenerating islet-derived 3 gamma , regenerating islet-derived 3 alpha

GENE ID SPEZIES
5068 Homo sapiens
19694 Mus musculus
171162 Rattus norvegicus
404114 Bos taurus
101829186 Mesocricetus auratus
403411 Canis lupus familiaris
459349 Pan troglodytes
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