Regenerating Islet-Derived 3 alpha Proteine (REG3A)

REG3A encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. Zusätzlich bieten wir Ihnen REG3A Antikörper (117) und REG3A Kits (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
REG3A 5068 Q06141
REG3A 19694 O09037
REG3A 171162 P35231
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Top REG3A Proteine auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Human Cells Maus His tag 100 μg 14 bis 16 Tage
$440.65
Details
Human Cells Human His tag 100 μg 14 bis 16 Tage
$570.06
Details
Human Cells Ratte Fc Tag 100 μg 14 bis 16 Tage
$440.65
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Escherichia coli (E. coli) Human GST tag 100 μg 11 Days
$356.40
Details
Escherichia coli (E. coli) Ratte His tag 100 μg 11 Days
$526.90
Details
Wheat germ Human GST tag 10 μg 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human REG3a Protein. 100 μg 11 bis 18 Tage
$682.25
Details

REG3A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
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Mouse (Murine) , ,

Rat (Rattus) , ,
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Am meisten referenzierte REG3A Proteine

  1. Human REG3A Protein expressed in Human Cells - ABIN3216396 : Orelle, Keim, Masciotra, Dagorn, Iovanna: Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. in The Journal of clinical investigation 1993 (PubMed)
    Show all 3 Pubmed References

Weitere Proteine zu Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartnern

Human Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartner

  1. Survival signal REG3alpha prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.

  2. REG3A SNP was not associated with aGVHD

  3. Results show that REG3beta binds the surface of extracellular vesicles (EVs), through its lectin domain, thereby interfering with the internalization of EVs by target cells and compromising their functionality. This mechanism could be important in pancreatic ductal adenocarcinoma (PDAC), since we detected REG3beta+ EVs in blood from PDAC patients.

  4. Data show that regenerating family member 3 alpha protein (REG3A) can modulate specific cutaneous inflammatory responses and that the decrease in cutaneous REG3A exacerbates toll-like receptor 3 (TLR3)-mediated inflammation in diabetic skin wounds.

  5. Data found that REG3A was significantly downregulated in Gastric cancer and closely related with patient prognoses. REG3A overexpression suppressed the invasion and proliferation promoting apoptosis of GC cells. While REG3A knockdown promoted the invasion, and proliferation suppressing

  6. Mice with hepatocytes that express hREG3A, which travels to the intestinal lumen, are less sensitive to colitis than control mice. Suggest reduced oxidative stress preserves the gut microbiota and its ability to prevent inflammation.

  7. The pancreas reacts to remote lesions and septic insults in mice and rats with increased PSP synthesis, while PAP is selectively responsive to septic events. Furthermore, our results suggest that serum PSP in septic patients is predominantly derived through an acute phase response of the pancreas.

  8. Data show that interleukin-2 receptor alpha, tumor necrosis factor receptor 1, serum STimulation-2 (IL1RL1 gene product), and regenerating islet-derived 3-alpha were significantly associated with non-relapse mortality.

  9. skin injury increases IL-36gamma via the activation of TLR3-SLUG-VDR axis and IL-36gamma induces REG3A to promote wound healing

  10. Association between a SNP in the REG3A gene, rs7588571, located upstream of the REG3A gene, and bone marrow transplant outcomes including the incidence of chronic GVHD. Since REG proteins control intestinal microbiota, and since intestinal dysbiosis is in part responsible for the development of GVHD, findings lead to the concept that REG3A could have some protective effect through the regulation of gut microbiota.

  11. Patients with high levels of PAP/REG3A had overall shorter survival as well as poor surgical outcomes with reduced disease-free survival.

  12. Serum REG3alpha is not an accurate diagnostic and predictive biomarker in Crohn's disease patients undergoing hemopoetic stem cell transplantation.

  13. Up-regulation of REG3A correlates with colorectal cancer risk.

  14. Regulation network analysis confirmed the cell growth related differentially expressed genes, and further uncovered three transcription factor families with immune functions regulated by REG3A

  15. Reg3alpha is an extracellular matrix-targeted reactive oxygen species scavenger that binds the fibrin scaffold resulting from hepatocyte death during acute liver failure.

  16. our findings reveal a dual and contextual pathophysiologic role for REG3beta during pancreatitis and pancreatic ductal adenocarcinoma initiation

  17. Reg3A overexpression promoted cell growth in pancreatic cancer. SOCS3 is a key target in cancer by inhibiting cell growth and inducing apoptosis. SOCS3 negatively regulated Reg3A-mediated cell growth in pancreatic cancer.

  18. Reg3beta-dependent accumulation of macrophages in the ischemic heart has a role in myocardial healing

  19. Serum regenerating islet-derived 3-alpha is a biomarker of mucosal enteropathies

  20. Both live and heat-inactivated Bifidobacterium breve induced the expression of REGIII-alpha, the human ortholog and homolog of REGIII-gamma, in human colonic epithelial cells (Caco-2).

Mouse (Murine) Regenerating Islet-Derived 3 alpha (REG3A) Interaktionspartner

  1. skin injury increases IL-36gamma via the activation of TLR3-SLUG-VDR axis and IL-36gamma induces REG3A to promote wound healing

  2. Reg3alpha is an extracellular matrix-targeted reactive oxygen species scavenger that binds the fibrin scaffold resulting from hepatocyte death during acute liver failure.

  3. Data show that regenerating islet-derived 3-alpha (REG3alpha) is a plasma biomarker of gastrointestinal tract graft-versus-host disease that can be combined with clinical stage and histologic grade to improve risk stratification of patients.

  4. Reg2, Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.

  5. Reg3alpha stimulates beta-cell replication, by activating Akt kinase and increasing the levels of cyclin D1/CDK4.

REG3A Protein Überblick

Protein Überblick

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit REG3A

  • regenerating family member 3 alpha (REG3A)
  • regenerating islet-derived 3 alpha (Reg3a)
  • regenerating islet-derived 3 alpha (REG3A)
  • AV063448 Protein
  • HIP Protein
  • HIP/PAP Protein
  • INGAP Protein
  • PAP Protein
  • PAP-H Protein
  • PAP1 Protein
  • Pap2 Protein
  • PapII Protein
  • PBCGF Protein
  • PTP Protein
  • REG-III Protein
  • REG3 Protein
  • REG3G Protein

Bezeichner auf Proteinebene für REG3A

PAP homologous protein , REG-3-alpha , hepatocarcinoma-intestine-pancreas , hepatointestinal pancreatic protein , human proislet peptide , pancreatic beta cell growth factor , pancreatitis-associated protein 1 , proliferation-inducing protein 34 , proliferation-inducing protein 42 , reg III-alpha , regenerating islet-derived protein 3-alpha , regenerating islet-derived protein III-alpha , RegIII (alpha) , generating islet-derived, mouse homolog 3 alpha , islet of Langerhans regenerating protein 3 , lithostathine 3 , pancreatitis-associated protein 2 , REG 3 , regIII , regenerating islet-derived protein 3 alpha , ICRF , PSP , REG , islet cells regeneration factor , islet of Langerhans regenerating protein , lithostathine , pancreatic stone protein , pancreatic thread protein , pancreatitis-associated protein , regenerating islet-derived 3 gamma , regenerating islet-derived 3 alpha

GENE ID SPEZIES
5068 Homo sapiens
19694 Mus musculus
171162 Rattus norvegicus
404114 Bos taurus
403411 Canis lupus familiaris
459349 Pan troglodytes
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