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RASSF1 encodes a protein similar to the RAS effector proteins. Zusätzlich bieten wir Ihnen Ras Association (RalGDS/AF-6) Domain Family Member 1 Antikörper (146) und Ras Association (RalGDS/AF-6) Domain Family Member 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Ras association (RalGDS/AF-6) domain family 1
, Ras association (RalGDS/AF-6) domain family member 1
, ras association domain-containing protein 1
, Ras association domain family 1
, cardiac-specific ras association domain family 1 protein
, pancreas-specific ras association domain family 1 protein
, tumor suppressor protein RDA32
, 123F protein
, RASSF1A tumor suppressor
, protein 123F2