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Probable guanine nucleotide exchange factor.
Showing 4 out of 4 products:
SAMD9, an IFN-gamma (zeige IFNG Proteine)-responsive protein, interacts with RGL2 to diminish the expression of EGR1 (zeige EGR1 Proteine), a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation.
Rgl2 and RalB (zeige Ralb Proteine) both localized to the leading edge, and this localization of RalB (zeige Ralb Proteine) was dependent on endogenous Rgl2 expression.
RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras (zeige HRAS Proteine). results of the present study indicate that Ras may distinguish between the different RalGDS (zeige RALGDS Proteine) family members by their phosphorylation by PKA.
The crystal structure of the mouse Rgl2 REM (zeige REM1 Proteine)- and a CDC25 (zeige CDC25C Proteine)-homology domain.
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
, ral guanine nucleotide dissociation stimulator-like 2
, ral guanine nucleotide dissociation stimulator-like 2-like
, GDS-related protein
, ralGDS-like 2
, ralGDS-like factor
, ras-associated protein RAB2L
, RalGDS-like factor
, ral guanine nucleotide dissociation stimulator,-like 2
, RAS oncogene family-like member RAB2