RASD Family, Member 2 Proteine (RASD2)

RASD2 encodes a Ras-related protein that enriched in striatum. Zusätzlich bieten wir Ihnen RASD Family, Member 2 Antikörper (98) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RASD2 23551 Q96D21
RASD2 171099 P63033
RASD2 75141 P63032
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Top RASD Family, Member 2 Proteine auf antikoerper-online.de

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,682.17
Details
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$318.85
Details

RASD2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Rat (Rattus) ,

Mouse (Murine) ,

Am meisten referenzierte RASD Family, Member 2 Proteine

  1. Human RASD2 Protein expressed in Wheat germ - ABIN1317482 : Harrison, Lahoste, Ruskin: Ontogeny and dopaminergic regulation in brain of Ras homolog enriched in striatum (Rhes). in Brain research 2008 (PubMed)

Weitere Proteine zu RASD Family, Member 2 (RASD2) Interaktionspartnern

Human RASD Family, Member 2 (RASD2) Interaktionspartner

  1. Study demonstrated that variation in the gene coding for RASD2 (rs6518956) affects in vivo prefrontal and striatal phenotypes in healthy human subjects that are relevant to schizophrenia

  2. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  3. Findings reveal that ras homolog enriched in striatum is localized also in striatal cholinergic interneurons and, most importantly, lack of this G-protein, significantly alters dopamine D2 receptor (zeige DRD2 Proteine) modulation of striatal cholinergic excitability.

  4. Rhes is reduced in the brains of Huntington's disease patients.

  5. The findings of this study suggested that Rhes may play a crucial role in striatal iron homeostasis.

  6. Rhes robustly binds the autophagy regulator Beclin-1 (zeige BECN1 Proteine), decreasing its inhibitory interaction with Bcl-2 (zeige BCL2 Proteine) independent of JNK-1 (zeige MAPK8 Proteine) signaling.

  7. The sequestering of Rhes through its binding to mutant huntingtin (zeige HTT Proteine) may decrease the ability of Rhes to perform vital physiological functions in the striatum neurons of Huntington disease (zeige HTT Proteine) patients. (Review)

  8. Rhes is an imidazoline-regulated transcript in pancreatic beta-cells

  9. Rhes can interfere with the functional activity of wt and mutated TSHr (zeige TSHR Proteine) and with the respective hormone-stimulated cAMP production of FSHr (zeige FSHR Proteine) and LHr (zeige LHCGR Proteine).

  10. The genes RASD2 might be vulnerability genes for neuropsychologically defined subgroups of schizophrenic patients.

Mouse (Murine) RASD Family, Member 2 (RASD2) Interaktionspartner

  1. guanine nucleotide exchange factor (zeige ARHGEF12 Proteine) RasGRP1 (zeige RASGRP1 Proteine) inhibited Rhes-mediated control of striatal motor activity in mice. RasGRP1 (zeige RASGRP1 Proteine) stabilized Rhes, increasing its synaptic accumulation in the striatum.

  2. that Rasd2 mutants display deficits in basal prepulse inhibition that, in turn, exacerbate gating disruption under psychotomimetic drug challenge

  3. Study showed that both genetic deletion of Rhes and pharmacological blockade of mTORC1 significantly attenuate dyskinesia development by reducing the sensitization of striato-nigral medium-sized spiny neurons to levodopa

  4. ectopic expression of Rhes in the cerebellum of N171-82Q mice, during the asymptomatic period led to an exacerbation of motor deficits, including loss of balance and motor incoordination with ataxia-like features

  5. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  6. Brain Rhes expression is decreased in a mouse model of Huntington's disease.

  7. Rhes robustly binds the autophagy regulator Beclin-1 (zeige BECN1 Proteine), decreasing its inhibitory interaction with Bcl-2 (zeige BCL2 Proteine) independent of JNK-1 (zeige MAPK8 Proteine) signaling.

  8. Rhes is necessary for Akt (zeige AKT1 Proteine) dephosphorylation by the striatal multi-protein complex

  9. behavioral symptoms of HD are regulated by Rhes

  10. This study demonstrated that Rhes-deleted mice are dramatically protected from neurotoxicity and motor dysfunction in a striatal-specific model of Huntington's disease elicited by 3-nitropropionic acid.

RASD Family, Member 2 (RASD2) Protein Überblick

Protein Überblick

This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades.

Genbezeichner und Symbole assoziert mit RASD Family, Member 2 Proteine (RASD2)

  • RASD family member 2 (RASD2)
  • RASD family, member 2 (Rasd2)
  • 4930526B11Rik Protein
  • AU045414 Protein
  • MGC:4834 Protein
  • RASD2 Protein
  • Rhes Protein
  • TEM-2 Protein
  • TEM2 Protein

Bezeichner auf Proteinebene für RASD Family, Member 2 Proteine (RASD2)

RASD family, member 2 , GTP-binding protein Rhes , Ras homolog enriched in striatum , tumor endothelial marker 2 , SE6C , ras homolog enriched in striatum

GENE ID SPEZIES
418057 Gallus gallus
470196 Pan troglodytes
527921 Bos taurus
23551 Homo sapiens
171099 Rattus norvegicus
481284 Canis lupus familiaris
75141 Mus musculus
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