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RASD2 Protein (Myc-DYKDDDDK Tag)

RASD2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2730533
  • Target Alle RASD2 Proteine anzeigen
    RASD2 (RASD Family, Member 2 (RASD2))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 2
    • 2
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses RASD2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human RASD2 / TEM2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RASD2 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RASD2 (RASD Family, Member 2 (RASD2))
    Andere Bezeichnung
    Rasd2,tem2 (RASD2 Produkte)
    Synonyme
    RASD2 Protein, MGC:4834 Protein, Rhes Protein, TEM2 Protein, 4930526B11Rik Protein, AU045414 Protein, TEM-2 Protein, RASD family member 2 Protein, RASD family, member 2 Protein, RASD2 Protein, Rasd2 Protein
    Hintergrund
    This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.
    Molekulargewicht
    30.2 kDa
    NCBI Accession
    NP_055125
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