anti-Protein-O-Mannosyltransferase 1 (POMT1) Antikörper

The protein encoded by POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. Zusätzlich bieten wir Ihnen Protein-O-Mannosyltransferase 1 Kits (9) und Protein-O-Mannosyltransferase 1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
POMT1 10585 Q9Y6A1
POMT1 99011 Q8R2R1
POMT1 84430 Q99PR0
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Top anti-Protein-O-Mannosyltransferase 1 Antikörper auf

Showing 10 out of 58 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-POMT1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow cytometric analysis of U251 cells using POMT1 Antibody (C-term) Cat.-No AP53389PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with POMT1 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert FACS, IHC (p), WB POMT1 Antibody (C-term) (ABIN656314) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of extract of various cells, using POMT1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB POMT1 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 9 bis 11 Tage
Human Kaninchen Unkonjugiert WB Western Blot: POMT1 Antibody [NBP2-19891] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert WB Western Blot: POMT1 Antibody [NBP1-60054] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage

Weitere Antikörper gegen Protein-O-Mannosyltransferase 1 Interaktionspartner

Human Protein-O-Mannosyltransferase 1 (POMT1) Interaktionspartner

  1. The child was found to carry a heterozygous missense mutation c.1939G>A (p.Ala647Thr) in exon 19 of the protein-O-mannosyltransferase 1 (POMT1) gene inherited from the mother and a heterozygous frameshift mutation c.2141delG (p.Trp714Ter) in exon 20 inherited from the father.

  2. These findings may expand phenotype and mutation spectrum of the POMT1 gene. Clinical diagnosis supplemented with molecular screening may result in more accurate diagnoses of, prognoses for, and improved genetic counselling for this disease

  3. O-mannosylation of cadherins and protocadherins does not require POMT1 and/or POMT2 in contrast to alpha-dystroglycan, and moreover, the O-Man glycans on cadherins are not elongated.

  4. results demonstrate functional and biochemical similarities between POMT1 and its orthologue from bakers' yeast Pmt4.

  5. Our results suggest that POMT activity is inversely proportional to clinical severity, and demonstrate that skin fibroblasts can be used for differential diagnosis of patients with alpha-dystroglycanopathies. We have provided clinical, histological, enzymatic and genetic evidence of POMT1 involvement in five unrelated Chinese patients.

  6. Inhibition of POMT1/2 in human mesencyhmal stem cells , resulted in complete abolishment of chondrogenesis and alterations of adipogenic and osteogenic potential together with a lethal effect during myogenic induction.

  7. report of 2 male siblings and an unrelated female with early onset muscular dystrophy and intellectual disability with minimal structural brain anomalies and no ocular abnormalities; a novel missense mutation (c.1958C>T; p.Pro653Leu) was identified

  8. Three patients with heterozygous POMT1 mutations showed left ventricular (LV) dilation and/or decrease in myocardial contractile force.

  9. the effects of replacing Arg(64), Glu(78) and Arg(138)residues in human POMT1 and POMT2 with Ala on complex formation and enzymatic activity were studied.

  10. the function of the gene products is only known for POMT1, POMT2, and POMGnT1, all responsible for the O-mannosylglycan biosynthesis

  11. the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.

  12. Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome

  13. Extracellular matrix and nuclear abnormalities in skeletal muscle of a patient with Walker-Warburg syndrome caused by POMT1 mutation.

  14. active enzyme complex of POMT1 and POMT2 suggests that the regulation of protein O-mannosylation is complex and appears to be required for normal structure and function of alpha-dystroglycan in muscle and brain

  15. The authors report on a patient with Walker-Warburg syndrome and a novel POMT1 mutation. The patient expressed alpha-dystroglycan core protein, but fully glycosylated alpha-DG antibody epitopes were absent, associated with loss of laminin-binding activity

  16. Results indicate that mutations in the protein O-mannosyltransferase 1 gene result in a defect of protein O-mannosylation in Walker-Warburg syndrome patients.

  17. the phenotype of glycosylation disorders linked to POMT1 mutations. Furthermore, the A200P mutation is part of a conserved core haplotype, indicating an ancestral founder mutation.

  18. human protein O-mannosyltransferases 1 and 2 form heterocomplexes which possess protein O-mannosyltransferase activity

  19. Several mutations were found in the Protein O-Mannosyltransferase 1 and 2 (POMT1 and POMT2) genes, and one mutation was found in each of the fukutin and fukutin-related protein (FKRP) genes.

  20. An inverse Alu-repeated DNA element within exon 3 is associated with Walker Warburg syndrome in French Caucasian families.

Mouse (Murine) Protein-O-Mannosyltransferase 1 (POMT1) Interaktionspartner

  1. during embryogenesis, Pomt1 is expressed in the neural tube, the developing eye, and the mesenchyme; targeted deletion of Pomt1 results in early embryonic lethality due to defects in the assembly of Reichert's membrane

Protein-O-Mannosyltransferase 1 (POMT1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit POMT1

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  • LGMD2K Antikörper
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Bezeichner auf Proteinebene für POMT1

dolichyl-phosphate-mannose--protein mannosyltransferase 1 , dolichyl-phosphate-mannose-protein mannosyltransferase , protein O-mannosyl-transferase 1 , protein O-mannosyltransferase 1

10585 Homo sapiens
617609 Bos taurus
99011 Mus musculus
84430 Rattus norvegicus
608039 Canis lupus familiaris
100525803 Sus scrofa
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