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The protein encoded by PTPRR is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen Protein tyrosine Phosphatase, Receptor Type, R Kits (11) und Protein tyrosine Phosphatase, Receptor Type, R Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PTPRR Primary Antibody für WB - ABIN519537
Menigatti, Cattaneo, Sabates-Bellver, Ilinsky, Went, Buffoli, Marquez, Jiricny, Marra: The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. in Molecular cancer 2010
The PTPRR genes were related to possible endophenotypes for suicidal behaviour such as anger, depression-anxiety and fatigue.
The development of MDD may be related with the polymorphism of ERK (zeige EPHB2 Antikörper)-rs12678428 and PTPRR-rs1513105.
Results show that PTPRR is an early and direct target of the androgen receptor which negatively regulates the RAS/ERK1/2 pathway suggesting that its loss in prostate cancer cells is one factor that might contribute to activation of the RAS/ERK1/2 pathway.
High expression of PTP receptors R and Z1 was observed in all examined cases of colorectal carcinoma, adenoma and normal colon tissue in this study.
The methylation index of PTPRR recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.
3 genes identified by association study and supported by ocular expression and/or replication, UHRF1BP1L, PTPRR, and PPFIA2 (zeige PPFIA2 Antikörper), are novel candidates for myopic development within the MYP3 locus that should be further studied.
Methylation of the PTPRR promoter has an important role in the metastasis and may be a biomarker of invasive cervical cancer
the protein tyrosine phosphatase receptor type R gene may play a role in conferring risk of major depressive disorder in females
expression of the PTPRR-1 isoform was inactivated in colorectal cancer cells as a result of de novo CpG island methylation and enrichment of transcription-repressive histone-tail marks, mainly H3K27me3
determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (zeige MAPK1 Antikörper)-specific protein tyrosine phosphatases
These findings indicate an important role for PTPRR in maintaining low basal mitogen-activated protein kinase (zeige MAPK1 Antikörper) activity in Purkinje cells.
The data of this study disclosed a distinct role for PTPRR in recognition memory and exploration of a new environment.
Results support the suggested link between PTPRR isoforms and cerebellar calcium ion homeostasis, and suggest an additional role in the process of cell-cell adhesion
The ERK2 (zeige MAPK1 Antikörper) docking groove is more restrictive and selective for its tyrosine phosphatase inactivators than for MEK1 (zeige MAP2K1 Antikörper)/2 and indicate that distinct ERK2 (zeige MAPK1 Antikörper) residues modulate the docking interactions with activating and inactivating effectors.
PTPBR7, was subject to N-terminal proteolytic processing, in between amino acid position 136 and 137, resulting in an additional, 65-kDa transmembrane PTPRR isoform.
Ptprr-/- mice displayed ataxia characterized by defects in fine motor coordination and balance skills.
PTP-SL, like PTPBR7, is a single membrane-spanning receptor-type protein tyrosine phosphatases.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.
, protein tyrosine phosphatase Cr1PTPase
, protein-tyrosine phosphatase NC-PTPCOM1
, protein-tyrosine phosphatase PCPTP1
, receptor-type tyrosine-protein phosphatase R
, protein tyrosine phosphatase PCPTP1
, tyrosine phosphatase CBPTP
, protein tyrosine phosphatase, receptor type, R
, protein tyrosine phosphatase, receptor type, Q
, Receptor-type tyrosine-protein phosphatase R
, receptor-type tyrosine-protein phosphatase R-like
, STEP-like PTPase
, phosphotyrosine phosphatase 13
, protein-tyrosine-phosphatase SL