anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) Antikörper

The protein encoded by PTPRB is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPRB Kits (22) und PTPRB Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTPRB 314843  
PTPRB 5787 P23467
PTPRB 19263 B2RU80
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Top anti-PTPRB Antikörper auf antikoerper-online.de

Showing 10 out of 24 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
k.A. Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$291.53
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of PTPRB using HuvEc whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Human Stomach Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$332.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Rat Liver Tissue. Figure. Western Blot; Sample: Recombinant PTPRB, Rat. 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$360.00
Details
Hund Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 13 Tage
$335.04
Details
Ratte Kaninchen Unkonjugiert IF/ICC, IHC, IP, WB Western blot analysis of Rat Liver Tissue. Western blot analysis of recombinant Rat PTPRB. 100 μg Anmelden zum Anzeigen 31 bis 36 Tage
$326.91
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$390.50
Details
Human Kaninchen Biotin WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details

Am meisten referenzierte anti-PTPRB Antikörper

  1. Cow (Bovine) Polyclonal PTPRB Primary Antibody für ELISA - ABIN4348614 : Winderlich, Keller, Cagna, Broermann, Kamenyeva, Kiefer, Deutsch, Nottebaum, Vestweber: VE-PTP controls blood vessel development by balancing Tie-2 activity. in The Journal of cell biology 2009 (PubMed)

Weitere Antikörper gegen PTPRB Interaktionspartner

Human Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) Interaktionspartner

  1. PTPRB was down-regulated in non-small-cell lung cancer patients and was associated with patient overall survival.

  2. STIM1-induced Ca(2+) signaling activates Pyk2 to inhibit the interaction of VE-PTP and VE-cadherin and hence increase endothelial permeability.

  3. Results provide evidence that PTPRB and PLCG1 mutations are driving events in a subset of secondary angiosarcomas.

  4. VE-PTP activates TIE2 and stabilizes retinal and choroidal blood vessels

  5. these results suggest that the polarized redistribution of VE-PTP in response to shear stress plays an important role in the regulation of endothelial cells function by blood flow.

  6. The endothelial phosphatase PTPRB, a negative regulator of vascular growth factor tyrosine kinases, harbored predominantly truncating mutations in 10 of 39 angiosarcoma tumors.

  7. zinc(II) ions regulate receptor protein-tyrosine phosphatase beta activity at picomolar concentrations.

  8. vascular endothelial protein tyrosine phosphatase contributes to endothelial morphogenesis. Silencing of VE-PTP expression was accompanied by increased VEGF receptor-2 tyrosine phosphorylation and activation of downstream signaling pathways.

  9. Suggest that VE-PTP, in cooperation with integrins, regulates the spreading and migration of endothelial cells during angiogenesis.

  10. The PTP1B has been observed over expressed in human breast cancer patients, suggesting its role in cell proliferation.

  11. the Ser127Gly polymorphism in PTPRB is associated with substance abuse vulnerability in three independent case-control samples, but was not associated with alcoholism in Japanese subjects

  12. These results reveal a novel role for HPTPbeta in modulating Ang-1-Tie2 signaling and endothelial cell survival.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) Interaktionspartner

  1. VEPTP (vascular endothelial protein tyrosine phosphatase) determines TIE2 response to ANGPT2. VEPTP is absent from lymphatic endothelium in mouse in vivo, permitting ANGPT2/TIE2-mediated lymphangiogenesis.

  2. PTPRB regulates branching morphogenesis in the mammary epithelium by modulating the response of the FGFR signalling pathway to FGF stimulation

  3. STIM1-induced Ca(2+) signaling activates Pyk2 to inhibit the interaction of VE-PTP and VE-cadherin and hence increase endothelial permeability.

  4. In the absence of Tie-2, VE-PTP inhibition destabilizes endothelial barrier integrity in agreement with the VE-cadherin-supportive effect of VE-PTP.

  5. The Lewis X epitope is mainly expressed on phosphacan/receptor protein tyrosine phosphatase beta (RPTPbeta) in the developing mouse brain.

  6. VE-PTP activates TIE2 and stabilizes retinal and choroidal blood vessels

  7. We suggest that lymphocyte binding to vascular cell adhesion molecule 1 triggers a signaling process that enables a VE-PTP substrate to dissociate VE-PTP from VE-cadherin, thereby facilitating efficient transmigration.

  8. We conclude that the role of Tie2 in maintenance of vascular quiescence involves VE-PTP-dependent dephosphorylation of VEGF receptor-2, and that VEGF receptor-2 activity regulates VE-cadherin tyrosine phosphorylation, endothelial cell polarity

  9. IGFBP-2 bound receptor protein tyrosine phosphatase beta, which led to its dimerization and inactivation. Analysis of aortas obtained from IGFBP-2(-/-) mice showed that receptor protein tyrosine phosphatase beta was activated.

  10. Suggest that VE-PTP, in cooperation with integrins, regulates the spreading and migration of endothelial cells during angiogenesis.

  11. Data show that vascular endothelial protein tyrosine phosphatase (VE-PTP) is a transmembrane binding partner of VE-cadherin that reduces the tyrosine phosphorylation of VE-cadherin and cell layer permeability.

  12. the activity of VE-PTP is not required for the initial formation of blood vessels, yet it is essential for their maintenance and remodeling.

  13. Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.

  14. expression of Ptprb in mouse brain after chronic morphine treatment was found to be up-regulated in some brain regions

  15. Data show that leukocytes interacting with endothelial cells rapidly dissociate VE-PTP from VE-cadherin, weakening endothelial cell contacts via a mechanism that requires plakoglobin but not beta-catenin.

  16. Dissociation of VE-PTP from VE-cadherin triggers the activation of Tie-2, leading to enhanced endothelial cell proliferation and enlargement of vascular structures through activation of Erk1/2.

PTPRB Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PTPRB

  • protein tyrosine phosphatase, receptor type B (PTPRB) Antikörper
  • receptor-type tyrosine-protein phosphatase beta (LOC100380677) Antikörper
  • protein tyrosine phosphatase, receptor type, B (Ptprb) Antikörper
  • protein tyrosine phosphatase, receptor type B (Ptprb) Antikörper
  • 3230402H02Rik Antikörper
  • C130094E24 Antikörper
  • HPTP-BETA Antikörper
  • HPTPB Antikörper
  • PTPB Antikörper
  • PTPRB Antikörper
  • Ptpz Antikörper
  • R-PTP-BETA Antikörper
  • Rptpb Antikörper
  • VE-PTP Antikörper
  • Veptp Antikörper

Bezeichner auf Proteinebene für PTPRB

protein tyrosine phosphatase, receptor type, B , Receptor-type tyrosine-protein phosphatase beta , receptor-type tyrosine-protein phosphatase beta-like , receptor-type tyrosine-protein phosphatase beta , VE-PTP , protein tyrosine phosphatase, receptor type, beta polypeptide , vascular endothelial protein tyrosine phosphatase , R-PTP-beta , protein-tyrosine phosphatase beta

GENE ID SPEZIES
718564 Macaca mulatta
100063580 Equus caballus
100380677 Salmo salar
100456419 Pongo abelii
100548729 Meleagris gallopavo
100582561 Nomascus leucogenys
314843 Rattus norvegicus
5787 Homo sapiens
19263 Mus musculus
100350989 Oryctolagus cuniculus
100720273 Cavia porcellus
100156181 Sus scrofa
481162 Canis lupus familiaris
505696 Bos taurus
417853 Gallus gallus
101121760 Ovis aries
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