Protein AF-10 (MLLT10) ELISA Kits

MLLT10 encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Zusätzlich bieten wir Ihnen MLLT10 Antikörper (130) und MLLT10 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MLLT10 8028 P55197
MLLT10 17354 O54826
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top MLLT10 ELISA Kits auf antikoerper-online.de

Showing 1 out of 1 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$380.00
Details

Weitere ELISA Kits für MLLT10 Interaktionspartner

Human Protein AF-10 (MLLT10) Interaktionspartner

  1. In a retroviral transduction/transplantation mouse model, mice transplanted with MLL/AF10(OM-LZ) cells harboring PTPN11 (zeige PTPN11 ELISA Kits)(wt) developed myelomonocytic leukemia. Those transplanted with cells harboring PTPN11 (zeige PTPN11 ELISA Kits)(G503A) -induced monocytic leukemia in a shorter latency. Adding PTPN11 (zeige PTPN11 ELISA Kits)(G503A) to MLL/AF10 affected cell proliferation, chemo-resistance, differentiation, in vivo BM recruitment/clonal expansion and faster progression.

  2. Our results provide evidence for new loci influencing abdominal visceral (BBS9, ADCY8, KCNK9) and subcutaneous (MLLT10/DNAJC1/EBLN1) fat, and confirmed a locus (THNSL2) previously reported to be associated with abdominal fat in women

  3. The PZP (zeige PZP ELISA Kits) domain of AF10 senses unmodified H3K27 to regulate DOT1L (zeige DOT1L ELISA Kits)-mediated methylation of H3K79.

  4. we report that variants at the MLLT10 locus are unlikely to alter risk of glioma, and they have no prognostic value among patients with high-grade tumors (glioblastoma).

  5. Results provide evidence that transformation driven by MLL fusions as well as the recurrent AML (zeige RUNX1 ELISA Kits)-associated NUP98 (zeige NUP98 ELISA Kits)-NSD1 fusion oncogene (zeige RAB1A ELISA Kits) is critically dependent on the ability of AF10 to stimulate DOT1L (zeige DOT1L ELISA Kits) activity.

  6. detection of PICALM (zeige PICALM ELISA Kits)-MLLT10 fusion transcript occurs in 7% of children with T-lineage ALL and is not associated with a poorer outcome for patients treated with contemporary, intensive chemotherapy

  7. In pediatric T-acute lymphoblastic leukemia, we have identified 2 RNA processing genes, that is, HNRNPH1 (zeige HNRNPH1 ELISA Kits)/5q35 and DDX3X (zeige DDX3X ELISA Kits)/Xp11.3 as new MLLT10 fusion partners.

  8. results strongly indicate that the differential regulation of these three genes is not due to the break point effect but as a consequence of the CALM/AF10 fusion gene expression, though the mechanism of regulation is not well understood

  9. In leukemia cells, full-length CALM-AF10 localized to the nucleus with no consistent effect on growth factor endocyctosis, and suppressed histone H3 lysine 79 methylation regardless of the presence of clathrin

  10. a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)) was identified.

Mouse (Murine) Protein AF-10 (MLLT10) Interaktionspartner

  1. Results provide evidence that transformation driven by MLL fusions as well as the recurrent AML (zeige RUNX1 ELISA Kits)-associated NUP98 (zeige NUP98 ELISA Kits)-NSD1 fusion oncogene (zeige RAB1A ELISA Kits) is critically dependent on the ability of AF10 to stimulate DOT1L (zeige DOT1L ELISA Kits) activity.

  2. During leukemogenesis, CALM-AF10 plays critical roles in the cytoplasm.

  3. In leukemia cells, full-length CALM-AF10 localized to the nucleus with no consistent effect on growth factor endocyctosis, and suppressed histone H3 lysine 79 methylation regardless of the presence of clathrin

  4. further suggest that future approaches to antagonize CALM-AF10-induced transformation should incorporate strategies, which aim at blocking these key domains

  5. conclude that Mllt10/Af10-Dot1l (zeige DOT1L ELISA Kits) are essential, largely dedicated activators of Wnt (zeige WNT2 ELISA Kits)-dependent transcription, critical for maintenance of intestinal proliferation and homeostasis

MLLT10 Antigen-Profil

Beschreibung des Gens

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Protein AF-10 (MLLT10) ELISA Kits

  • MLLT10, histone lysine methyltransferase DOT1L cofactor (MLLT10) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 (Mllt10) Antikörper
  • Af10 Antikörper
  • B130021D15Rik Antikörper
  • D630001B22Rik Antikörper
  • mKIAA4140 Antikörper

Bezeichner auf Proteinebene für Protein AF-10 (MLLT10) ELISA Kits

ALL1-fused gene from chromosome 10 protein , protein AF-10 , type I AF10 protein , type III AF10 protein , type IV AF10 protein , myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog

GENE ID SPEZIES
8028 Homo sapiens
17354 Mus musculus
Ausgewählte Anbieter für MLLT10 (MLLT10) ELISA Kits
Haben Sie etwas anderes gesucht?