anti-Proline-Rich Transmembrane Protein 2 (PRRT2) Antikörper

PRRT2 encodes a transmembrane protein containing a proline-rich domain in its N-terminal half. Zusätzlich bieten wir Ihnen PRRT2 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRRT2 112476 Q7Z6L0
PRRT2 69017  
PRRT2    
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Top anti-PRRT2 Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Western Blot: PRRT2 Antibody [NBP1-84168] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue Immunohistochemistry-Paraffin: PRRT2 Antibody [NBP1-84168] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in cells in granular layer. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB PRRT2 Antibody (Center)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRRT2 antibody detected the PRRT2 protein (arrow). Overlay histogram showing U-2 OS cells stained with ABIN2849225(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2849225, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western blot analysis of PRRT2 in mouse brain tissue with PRRT2 polyclonal antibody  at 1 ug/mL. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$355.73
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$350.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB Anti-PRRT2 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$523.71
Details
Human Maus Unkonjugiert WB Western Blot analysis of PRRT2 expression in transfected 293T cell line by PRRT2 MaxPab polyclonal antibody.<br><br>Lane 1: PRRT2 transfected lysate(37.4 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details
Human Kaninchen APC ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen Biotin ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

Weitere Antikörper gegen PRRT2 Interaktionspartner

Human Proline-Rich Transmembrane Protein 2 (PRRT2) Interaktionspartner

  1. This study showed that there is no significant difference in the the age at onset between the PKD (zeige PRKD1 Antikörper) patients with (n = 27) and without (n = 46) PRRT2 mutation.

  2. miR (zeige MLXIP Antikörper)-30b promotes glioblastoma cell proliferation, migration, and invasion via targeting PRRT2.

  3. Results identified PRRT2 and DAB2IP (zeige DAB2IP Antikörper) to be frequently mutated in all different cancer cell line types. Further analysis showed that both genes were also frequently mutated in colorectal and endometrial cancer patient samples. Functional studies revealed PRRT2 to be implicated in cellular proliferation and migration with the truncated microsatellite instability-derived PRRT2 form promoting both processes.

  4. the expression level of PRRT2 was much higher in the human brain than in other human tissues, thus providing experimental evidence for a potential relationship between PRRT2 and neurogenesis. To the best of our knowledge, this study is the first to report the expression pattern of PRRT2 in human tissues.

  5. PRRT2 mutations have roles in neuronal dysfunction and neurodevelopmental defects

  6. The cases reported here constitute the first genetic-confirmed series of paroxysmal kinesigenic dyskinesia (PKD (zeige PRKD1 Antikörper)) in Hong Kong. The PRRT2 c.649dupC screening is recommened for all patients with all forms of PKD (zeige PRKD1 Antikörper).

  7. Data show that proline-rich transmembrane protein 2 (PRRT2) is decreased in glioma and is targeted by microRNA miR (zeige MLXIP Antikörper)-30a-5p.

  8. These findings indicate a novel role for zinc regulation in the PKCalpha (zeige PKCa Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway and explain an important mechanism for controlling of stem cell program in lung cancer cells.

  9. PRRT2 mutations most likely not associated with benign epilepsy with centrotemporal spikes in Chinese mainland population.

  10. Exome sequencing was conducted and a duplication mutation c.649dupC (p.R217Pfs*8) in the proline-rich transmembrane protein 2 gene (PRRT2) was identified in patients with febrile seizures.

Mouse (Murine) Proline-Rich Transmembrane Protein 2 (PRRT2) Interaktionspartner

  1. Study describes the phenotype of KO mice for PRRT2 and shows that its loss-of-function recapitulates the human phenotype in terms of episodic disturbances in motor coordination and paroxysmal dyskinesias, suggesting that PRRT2 plays a critical role in the development of cortical connectivity and functional stability of neuronal networks.

  2. PRRT2 mutations have roles in neuronal dysfunction and neurodevelopmental defects

  3. PRRT2 interacts with the Src (zeige SRC Antikörper) homology 3 domain-bearing protein Intersectin 1 (zeige ITSN1 Antikörper), an intracellular protein (zeige CKAP2 Antikörper) involved in synaptic vesicle cycling.

  4. Mutants associated with paroxysmal kinesigenic dyskinesia with infantile convulsions C lead to dramatically reduced PRRT2 levels.

PRRT2 Antigen-Profil

Protein Überblick

This gene encodes a transmembrane protein containing a proline-rich domain in its N-terminal half. Studies in mice suggest that it is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. Mutations in this gene are associated with episodic kinesigenic dyskinesia-1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PRRT2

  • proline rich transmembrane protein 2 (PRRT2) Antikörper
  • proline-rich transmembrane protein 2 (Prrt2) Antikörper
  • 1500031I19Rik Antikörper
  • AI195361 Antikörper
  • BFIC2 Antikörper
  • BFIS2 Antikörper
  • DSPB3 Antikörper
  • DYT10 Antikörper
  • EKD1 Antikörper
  • ICCA Antikörper
  • IFITMD1 Antikörper
  • PKC Antikörper

Bezeichner auf Proteinebene für PRRT2

dispanin subfamily B member 3 , interferon induced transmembrane protein domain containing 1

GENE ID SPEZIES
112476 Homo sapiens
69017 Mus musculus
100444066 Pongo abelii
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